Etelcalcetide
- CAS No.
- 1262780-97-1
- Chemical Name:
- Etelcalcetide
- Synonyms
- Parsavib;Etelcalcetide;Etelcalcetide HCI;AMG-416 (Velcalcetide);D-Argininamide, N-acetyl-D-cysteinyl-D-alanyl-D-arginyl-D-arginyl-D-arginyl-D-alanyl-, disulfide with L-cysteine;D-Argininamide, N-acetyl-D-cysteinyl-D-alanyl-D-arginyl-D-arginyl-D-arginyl-D-alanyl-, disulfide with L-cysteine (ACI);S-(((S)-2-Acetamido-3-(((R)-1-(((R)-1-(((R)-1-(((R)-1-(((R)-1-(((R)-1-amino-5-guanidino-1-oxopentan-2-yl)amino)-1-oxopropan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)amino)-1-oxopropan-2-yl)amino)-3-oxopropyl)thio)-L-cysteine
- CBNumber:
- CB53154325
- Molecular Formula:
- C38H73N21O10S2
- Molecular Weight:
- 1048.25
- MDL Number:
- MFCD31735128
- MOL File:
- 1262780-97-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Etelcalcetide | FE162097 | 50mg | $649 |
| Etelcalcetide | FE162097 | 100mg | $779 |
| Etelcalcetide | FE162097 | 250mg | $1167.5 |
| (2R)-2-amino-3-{[(2S)-2-{[(1R)-1-{[(1R)-4-carbamimidamido-1-{[(1R)-4-carbamimidamido-1-{[(1R)-4-carbamimidamido-1-{[(1R)-1-{[(1R)-4-carbamimidamido-1-carbamoylbutyl]carbamoyl}ethyl]carbamoyl}butyl]carbamoyl}butyl]carbamoyl}butyl]carbamoyl}ethyl]carbamoyl}-2-acetamidoethyl]disulfanyl}propanoic acid 98%byHPLC | AA01EGPV | 5mg | $465 |
| (2R)-2-amino-3-{[(2S)-2-{[(1R)-1-{[(1R)-4-carbamimidamido-1-{[(1R)-4-carbamimidamido-1-{[(1R)-4-carbamimidamido-1-{[(1R)-1-{[(1R)-4-carbamimidamido-1-carbamoylbutyl]carbamoyl}ethyl]carbamoyl}butyl]carbamoyl}butyl]carbamoyl}butyl]carbamoyl}ethyl]carbamoyl}-2-acetamidoethyl]disulfanyl}propanoic acid 98%byHPLC | AA01EGPV | 10mg | $756 |
| Density | 1.58±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| pka | 2.01±0.10(Predicted) |
| Sequence | H-Cys(1)-OH,Ac-D-Cys(1)-D-Ala-D-Arg-D-Arg-D-Arg-D-Ala-D-Arg-NH2(Disulfide bridge Cys1-(D-Cys1))/C(1),Ac-（D-C（1）-（D-A）-（D-R）-（D-R）-（D-R）-（D-A）-（D-R）-NH2(Disulfide bridge Cys1-(D-Cys1)) |
| InChIKey | HQGWMVNIZKNABK-TZUZSESWNA-N |
| FDA UNII | 60ME133FJB |
| NCI Drug Dictionary | etelcalcetide |
| ATC code | H05BX04 |
Etelcalcetide price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FE162097 | Etelcalcetide | 1262780-97-1 | 50mg | $649 | 2026-06-04 | Buy |
| Biosynth | FE162097 | Etelcalcetide | 1262780-97-1 | 100mg | $779 | 2026-06-04 | Buy |
| Biosynth | FE162097 | Etelcalcetide | 1262780-97-1 | 250mg | $1167.5 | 2026-06-04 | Buy |
| aablocks | AA01EGPV | (2R)-2-amino-3-{[(2S)-2-{[(1R)-1-{[(1R)-4-carbamimidamido-1-{[(1R)-4-carbamimidamido-1-{[(1R)-4-carbamimidamido-1-{[(1R)-1-{[(1R)-4-carbamimidamido-1-carbamoylbutyl]carbamoyl}ethyl]carbamoyl}butyl]carbamoyl}butyl]carbamoyl}butyl]carbamoyl}ethyl]carbamoyl}-2-acetamidoethyl]disulfanyl}propanoic acid 98%byHPLC | 1262780-97-1 | 5mg | $465 | 2026-05-30 | Buy |
| aablocks | AA01EGPV | (2R)-2-amino-3-{[(2S)-2-{[(1R)-1-{[(1R)-4-carbamimidamido-1-{[(1R)-4-carbamimidamido-1-{[(1R)-4-carbamimidamido-1-{[(1R)-1-{[(1R)-4-carbamimidamido-1-carbamoylbutyl]carbamoyl}ethyl]carbamoyl}butyl]carbamoyl}butyl]carbamoyl}butyl]carbamoyl}ethyl]carbamoyl}-2-acetamidoethyl]disulfanyl}propanoic acid 98%byHPLC | 1262780-97-1 | 10mg | $756 | 2026-05-30 | Buy |
Etelcalcetide Chemical Properties,Uses,Production
Uses
N-Acetyl-D-cysteinyl-D-alanyl-D-arginyl-D-arginyl-D-arginyl-D-alanyl- D-Argininamide-L-cysteine Disulfide is a useful research chemical used in the treatment of chronic kidney disease-mineral and bone disorder.
Definition
ChEBI: Etelcalcetide is an oligopeptide.
Mechanism of action
Etelcalcetide is a calcimimetic agent that allosterically modulates the calcium-sensing receptor (CaSR). Etelcalcetide binds to the CaSR and enhances activation of the receptor by extracellular calcium. Activation of the CaSR on parathyroid chief cells decreases PTH secretion.
Clinical Use
Synthetic peptide calcimimetic agent:Treatment of secondary hyperparathyroidism in patients on haemodialysis
Drug interactions
Potentially hazardous interactions with other drugs Avoid with cinacalcet.
Metabolism
Etelcalcetide is biotransformed in blood by reversible disulphide exchange with endogenous thiols to predominantly form conjugate with serum albumin
Etelcalcetide Preparation Products And Raw materials
Raw materials
Preparation Products
Etelcalcetide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| LEON (NANJING) BIOTECHNOLOGY CO., LTD. | 15051830413 | sales.njleonbiotech@gmail.com | China | 5482 | 58 |
| RongNa Biotechnology Co.,Ltd | +86-86-13583358881 +8618560316533 | Brad@rongnabiotech.com | China | 3372 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +86-17331189928 | admin@guyunchem.com | China | 615 | 58 |
| Chongqing Soarwin Technology Co., Ltd | +86-15790943001 | crystal@sorawin.cn | China | 421 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29812 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10403 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19936 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49979 | 58 | |
| Hebei Yanxi Chemical Co., Ltd. | +86-17531190177 | faithe@yan-xi.com | China | 5853 | 58 |
| Hubei Ipure Biology Co., Ltd | +8618062405514 | ada@ipurechemical.com | China | 10236 | 58 |
View Lastest Price from Etelcalcetide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-31 | Etelcalcetide
1262780-97-1
|
$1.00 | 1g | 99% | 100kg | RongNa Biotechnology Co.,Ltd | |
 |
2026-07-06 | Etelcalcetide
1262780-97-1
|
$75.00-750.00 | 10kg | 0.99 | 20tons | Zibo Hangyu Biotechnology Development Co., Ltd | |
 |
2025-08-20 | Etelcalcetide
1262780-97-1
|
1Box | 99.99% | 10 Boxes | Chongqing Soarwin Technology Co., Ltd |
-
- Etelcalcetide
1262780-97-1
- $1.00
- 99%
- RongNa Biotechnology Co.,Ltd
-
- Etelcalcetide
1262780-97-1
- $75.00-750.00
- 0.99
- Zibo Hangyu Biotechnology Development Co., Ltd
-
- Etelcalcetide
1262780-97-1
- 99.99%
- Chongqing Soarwin Technology Co., Ltd
