Dermorphin
- CAS No.
- 77614-16-5
- Chemical Name:
- Dermorphin
- Synonyms
- DERMORPHIN ACETATE;DERMORPHIN;Dermorphin 5mg;Dermorphin HAc;dermorphin ，DR5;dermorphin ，DR10;Dermorphin Powder;Dermorphin/5mg/10mg;dermorphin/DERMORPHIN ACETATE;Dermorphin trifluoroacetate salt
- CBNumber:
- CB5498044
- Molecular Formula:
- C40H50N8O10
- Molecular Weight:
- 802.87
- MDL Number:
- MFCD00076694
- MOL File:
- 77614-16-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Dermorphin (acetate) ≥95% | 31607 | 1mg | $36 |
| Dermorphin (acetate) ≥95% | 31607 | 5mg | $153 |
| Dermorphin (acetate) ≥95% | 31607 | 10mg | $268 |
| Dermorphin (acetate) ≥95% | 31607 | 25mg | $587 |
| Dermorphin acetate | FD182310 | 0.1g | $249.56 |
| More product size | |||
| Melting point | 157-159 °C |
|---|---|
| Boiling point | 1323.8±65.0 °C(Predicted) |
| Density | 1.363±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Soluble in DMSO |
| form | powder |
| pka | 9.83±0.15(Predicted) |
| color | white to off-white |
| Sequence | H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2 |
| InChIKey | FHZPGIUBXYVUOY-VWGYHWLBSA-N |
| SMILES | C(N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N)(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](C)NC(=O)[C@@H](N)CC1C=CC(O)=CC=1)CC1C=CC=CC=1)CC1C=CC(O)=CC=1 |
| FDA UNII | 2SEC01B703 |
Dermorphin price More Price(48)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 31607 | Dermorphin (acetate) ≥95% | 1mg | $36 | 2026-04-30 | Buy | |
| Cayman Chemical | 31607 | Dermorphin (acetate) ≥95% | 5mg | $153 | 2026-04-30 | Buy | |
| Cayman Chemical | 31607 | Dermorphin (acetate) ≥95% | 10mg | $268 | 2026-04-30 | Buy | |
| Cayman Chemical | 31607 | Dermorphin (acetate) ≥95% | 25mg | $587 | 2026-04-30 | Buy | |
| Biosynth | FD182310 | Dermorphin acetate | 0.1g | $249.56 | 2026-06-04 | Buy |
Dermorphin Chemical Properties,Uses,Production
Structure
Dermorphin does not contain the common N-terminal sequence for the traditional endogenous opioid peptides (Tyr–Gly–Gly–Phe), and its sequence is completely different from those of the endomorphins, which were identified as endogenous μ-opioid peptides that also do not contain the common sequence. Interestingly, DM contains D-alanine (a D-isomer amino acid) in its sequence. The primary structure of dermorphin is YDAFGYPS-NH2.
Description
Dermorphin was first isolated from the skin of the skin of South American frogs of the genus Phyllomedusa. It is a high potency natural opiate peptide that binds selectively to mu-opioid receptors.
Uses
A mu-opioid receptor agonist
Definition
ChEBI: Dermorphin is an oligopeptide.
Side effects
Like μ-opiate agonists, dermorphins produce antinociception and also catalepsy, respiratory depression, constipation, tolerance, and dependence, although at a lower degree than morphine does[1].
in vitro
Dermorphin, a peptide isolated from the skin of Phyllomedusa frogs and the peptide receptor (NOP) component by the endogenous agonist nociceptin/orphanin FQ (N/OFQ). In displacement binding studies at CHOhMu, Dermorphin and DeNo displac the binding of [3H]-DPN in a concentration dependent and saturable manner. Dermorphin displays an affinity of 7.17, while N/OFQ fails to displace [3H]-DPN at the Delta receptor. Dermorphin and DeNo stimulate the binding of GTPγ[35S] in a concentration dependent and saturable manner at the Mu receptor.
References
[1] Negri, L. P. Melchiorri and R. Lattanzi. “Opioid and Bv8 Peptides.”Handbook of Biologically Active Peptides (Second Edition) 2013:376-383.
Dermorphin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 | xinshengkeji@xsmaterial.com | China | 1085 | 58 |
| Hebei Weimiao Import and Export Trade Co., Ltd. | +86-19948166995 | sale01@hbweimiao.com | China | 76 | 58 |
| Hebei Xunou new energy Technology Co., LTD | +86-17531957005; +86-008617531957005 | xunou8@hbxunou.com | China | 36 | 58 |
| Strong peptide cross-border e-commerce Co. LTD | 13930052870 | qt01@qiangtaipharm.com | China | 84 | 58 |
| Shenzhen Aoxi Technology Co., Ltd. | +852-46424790 | frank88rawpowder@outlook.com | China | 162 | 58 |
| TsurgeX Pharmaceutical Technology Co., Ltd. | 13393959797 | master@tsurgex.com | China | 44 | 58 |
| Guangzhou Pros Bio Technology Co., Ltd. | +86-15373916629 | andrew19770118@gmail.com | China | 114 | 58 |
| HUARONG(GUANGDONG) PHARMACEUTICAL CO.,LTD | +86-0086-13751168070 +86-19925801629 | sales@huarongpharma.com | China | 185 | 58 |
| Hebei Dangtong Import and export Co LTD | +86-86-4001020630 +86-13910575315 | admin@hbdangtong.com | China | 1000 | 58 |
| Anhui Zhongda Biotechnology Co., Ltd | +86-19956560829 | justine@zhongda-biotech.com | China | 286 | 58 |
View Lastest Price from Dermorphin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-31 | DERMORPHIN ACETATE
77614-16-5
|
$1.00 | 1g | 99% | 100kg | RongNa Biotechnology Co.,Ltd
|
|
 |
2026-07-31 | Dermorphin
77614-16-5
|
$1.00 | 1box | 99% | 100000 | Tianjin Shunzhicheng Technology Co., Ltd. | |
 |
2026-07-31 | dermorphin
77614-16-5
|
$5.00 | 10mg | 99% HIGH PURITY | 5000tons | Shanghai Zheng Peptide Plastic Co., Ltd. |
-
- DERMORPHIN ACETATE
77614-16-5
- $1.00
- 99%
- RongNa Biotechnology Co.,Ltd
-
- Dermorphin
77614-16-5
- $1.00
- 99%
- Tianjin Shunzhicheng Technology Co., Ltd.
-
- dermorphin
77614-16-5
- $5.00
- 99% HIGH PURITY
- Shanghai Zheng Peptide Plastic Co., Ltd.
