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ChemicalBook >> CAS DataBase List >>N'-Cbz-L-ornithine

N'-Cbz-L-ornithine

CAS No.
3304-51-6
Chemical Name:
N'-Cbz-L-ornithine
Synonyms
Z-ORN-OH;H-ORN(Z)-OH;Orn(Z);N-ORN(Z)-OH;l-orn(z)-oh;L-Orn(Cbz)-OH;N-D-CBZ-L-ORN;H-L-ORN(Z)-OH;H-ORN(CBZ)-OH;N5-Cbz-Orn-OH
CBNumber:
CB5343696
Molecular Formula:
C13H18N2O4
Molecular Weight:
266.29
MDL Number:
MFCD00037220
MOL File:
3304-51-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 05:28:06
Product description Number Pack Size Price
Nd-Z-L-ornithine Asreported 285603 10g $333
Nd-Z-L-ornithine Asreported 285603 25g $463
Nd-Z-L-ornithine Asreported 285603 50g $679
Nd-Z-L-ornithine Asreported 285603 100g $922
Nd-Z-L-ornithine Asreported 285603 250g $1271
More product size

N'-Cbz-L-ornithine Properties

Melting point 248-252℃
Boiling point 492.2±45.0 °C(Predicted)
Density 1.234±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility Acidic Alcohol (Sparingly), Aqueous Acid (Slightly)
pka 2.51±0.24(Predicted)
form Solid
color White
InChI 1S/C13H18N2O4/c14-8-4-7-11(12(16)17)15-13(18)19-9-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9,14H2,(H,15,18)(H,16,17)/t11-/m0/s1
InChIKey ZYGRWJVRLNJIMR-NSHDSACASA-N
SMILES NCCC[C@H](NC(=O)OCc1ccccc1)C(O)=O
CAS DataBase Reference 3304-51-6(CAS DataBase Reference)
UNSPSC Code 12352209

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
WGK Germany  3
Storage Class 11 - Combustible Solids
NFPA 704
1
0 0

N'-Cbz-L-ornithine price More Price(62)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 285603 Nd-Z-L-ornithine Asreported 3304-51-6 10g $333 2026-06-03 Buy
Usbiological 285603 Nd-Z-L-ornithine Asreported 3304-51-6 25g $463 2026-06-03 Buy
Usbiological 285603 Nd-Z-L-ornithine Asreported 3304-51-6 50g $679 2026-06-03 Buy
Usbiological 285603 Nd-Z-L-ornithine Asreported 3304-51-6 100g $922 2026-06-03 Buy
Usbiological 285603 Nd-Z-L-ornithine Asreported 3304-51-6 250g $1271 2026-06-03 Buy
Product number Packaging Price Buy
285603 10g $333 Buy
285603 25g $463 Buy
285603 50g $679 Buy
285603 100g $922 Buy
285603 250g $1271 Buy

N'-Cbz-L-ornithine Chemical Properties,Uses,Production

Chemical Properties

White powder

Uses

L-Orn(Z)-OH is used as a reactant in the synthesis of cyclic aminohexapeptides which showed antifungal activity.

Synthesis

L(+)-Ornithine hydrochloride

3184-13-2

Benzyl chloroformate

501-53-1

N'-Cbz-L-ornithine

3304-51-6

The general procedure for the synthesis of (S)-2-amino-5-(((benzyloxy)carbonyl)amino)pentanoic acid from L-ornithine hydrochloride and benzyl chloroformate was as follows: 7.5 g of L-ornithine hydrochloride was dissolved in 89 mL of 0.5 mol/L sodium hydroxide solution, 5.55 g of anhydrous copper sulfate was added, and the reaction was carried out for 15 minutes. Subsequently, 6.15 g of anhydrous potassium carbonate and 8.2 mL of benzyl chloroformate were added and the reaction mixture was stirred at room temperature overnight. After completion of the reaction, the filtrate was washed to give a blue solid. The solid was treated with saturated disodium ethylenediaminetetraacetic acid solution, which was first heated to reflux for 2 hours and then left at room temperature overnight. Finally, the filtrate was filtered and dried to give a white solid product in 83% yield.

References

[1] Patent: CN104788431, 2017, B. Location in patent: Paragraph 0055; 0056
[2] Journal of Labelled Compounds and Radiopharmaceuticals, 2009, vol. 52, # 2, p. 29 - 32
[3] Tetrahedron, 1999, vol. 55, # 33, p. 10201 - 10220
[4] Journal of the Chemical Society [Section] C: Organic, 1971, p. 3743 - 3748
[5] Journal of Agricultural and Food Chemistry, 1999, vol. 47, # 3, p. 939 - 944

N'-Cbz-L-ornithine Preparation Products And Raw materials

Global( 210)Suppliers
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L-ORNITHINE(CBZ) H-ORN(CBZ)-OH Orn(Z) L-Orn(Cbz)-OH Nd-Z-L-ornithine≥ 98% (HPLC) H-L-ORN(Z)-OH N-D-CBZ-L-ORN N-DELTA-Z-L-ORNITHINE N-DELTA-BENZYLOXYCARBONYL-L-ORNITHINE N-DELTA-CARBOBENZOXY-L-ORNITHINE N-DELTA-CARBOBENZYLOXY-L-ORNITHINE N-DELTA-CBZ-L-ORNITHINE N-ORN(Z)-OH ORNITHINE(Z)-OH N-?-CBZ-L-Ornithine N-?-Carbobenzyloxy-L-ornithine N-5-BENZYLOXYCARBONYL-L-ORNITHINE N5-benzyloxycarbonyl-L-ornithine N--Benzyloxycarbonyl-L-ornithine l-orn(z)-oh N'-Cbz-L-ornithine Z-L-ORNITHINE extrapure (S)-2-Amino-5-[[(benzyloxy)carbonyl]amino]pentanoic acid N5-[(Phenylmethoxy)carbonyl]-L-ornithine N5-Cbz-Orn-OH 2-amino-5-(benzyloxycarbonylamino)valeric acid 2-amino-5-(phenylmethoxycarbonylamino)pentanoic acid 2-azanyl-5-(phenylmethoxycarbonylamino)pentanoic acid N-D-BENZYLOXYCARBONYL-LORNITHINE N-Δ-Z-L-ORNITHINE (2S)-2-amino-5-{[(benzyloxy)carbonyl]amino}pentanoic acid N5-Cbz-L-ornithine Ornithine, N5-[(phenylmethoxy)carbonyl]- L-Ornithine, N5-[(phenylmethoxy)carbonyl]- N^d-Benzyloxycarbonyl-L-ornithine,98% N'-Cbz-L-ornithine USP/EP/BP Nδ-Cbz-L-ornithine H-ORN(Z)-OH Z-ORN-OH 3304-51-6 Modified Amino Acids I - Z BioChemical Biochemicals and Reagents Amino Acids and Peptides Ornithine [Org] Amino Acids and Derivatives Z-Amino acid series Amino Acids
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