Imperatorin
- CAS No.
- 482-44-0
- Chemical Name:
- Imperatorin
- Synonyms
- AMMIDIN;MARMELOSIN;2-g)(1)benzopyran-7-one,9-((3-methyl-2-butenyl)oxy)-7h-furo(;Marmelide;Pentosalen;NSC 402949;Imperatori;8-ISOAMYLEN;IMPERATORIN;AKOS 214-72
- CBNumber:
- CB5355754
- Molecular Formula:
- C16H14O4
- Molecular Weight:
- 270.28
- MDL Number:
- MFCD00016881
- MOL File:
- 482-44-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Imperatorin ≥98% (HPLC), powder | I6659 | 5mg | $163 |
| Imperatorin European Pharmacopoeia (EP) Reference Standard | Y0001205 | 20 mg | $254 |
| Imperatorin >98.0%(HPLC) | I0904 | 25mg | $65 |
| Imperatorin >98.0%(HPLC) | I0904 | 100mg | $174 |
| Imperatorin ≥98% | 26070 | 10mg | $82 |
| More product size | |||
| Melting point | 98-100°C |
|---|---|
| Boiling point | 333.4°C (rough estimate) |
| Density | 1.1311 (rough estimate) |
| refractive index | 1.4350 (estimate) |
| storage temp. | -20°C |
| solubility | DMSO: ≥5mg/mL |
| form | powder |
| color | off-white to light brown |
| λmax | 301nm(MeOH)(lit.) |
| Merck | 14,4925 |
| Major Application | food and beverages |
| InChI | InChI=1S/C16H14O4/c1-10(2)5-7-19-16-14-12(6-8-18-14)9-11-3-4-13(17)20-15(11)16/h3-6,8-9H,7H2,1-2H3 |
| InChIKey | OLOOJGVNMBJLLR-UHFFFAOYSA-N |
| SMILES | C1(=O)OC2=C(OC/C=C(\C)/C)C3OC=CC=3C=C2C=C1 |
| LogP | 2.983 (est) |
| CAS DataBase Reference | 482-44-0(CAS DataBase Reference) |
| FDA UNII | K713N25C78 |
| NIST Chemistry Reference | 7H-furo[3,2-g][1]benzopyran-7-one, 9-[(3-methyl-2-butenyl)oxy]-(482-44-0) |
| UNSPSC Code | 85151701 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312+P330-P501 | |||||||||
| target organs | Respiratory system | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | LV1575000 | |||||||||
| HS Code | 29419090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 Skin Sens. 1 STOT SE 3 |
|||||||||
| Hazardous Substances Data | 482-44-0(Hazardous Substances Data) | |||||||||
| NFPA 704 |
|
Imperatorin price More Price(122)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | I6659 | Imperatorin ≥98% (HPLC), powder | 482-44-0 | 5mg | $163 | 2026-04-30 | Buy |
| Sigma-Aldrich | Y0001205 | Imperatorin European Pharmacopoeia (EP) Reference Standard | 482-44-0 | 20 mg | $254 | 2026-04-30 | Buy |
| TCI Chemical | I0904 | Imperatorin >98.0%(HPLC) | 482-44-0 | 25mg | $65 | 2026-04-30 | Buy |
| TCI Chemical | I0904 | Imperatorin >98.0%(HPLC) | 482-44-0 | 100mg | $174 | 2026-04-30 | Buy |
| Cayman Chemical | 26070 | Imperatorin ≥98% | 482-44-0 | 10mg | $82 | 2026-04-30 | Buy |
Imperatorin Chemical Properties,Uses,Production
Description
Imperatorin is a kind of furocoumarin and phytochemical that present in citrus fruits. It could be isolated from Urena lobata L. (Malvaceae). It is biosynthesized from Umbelliferae in vivo. It has been found that it has anti-hypertrophic and anti-convulsant effects, and is useful in the HIV-1 research. Previous studies have shown that Imperatorin requires the transcription factor Sp1 to exert its inhibitory effect on the HIV-1. It can further inhibit the expression of cyclin D1 to cause cell cycle arrest at G1 stage. Moreover, it can suppress the HIV-1 replication inside the primary T lymphocytes and transformed cell lines. This inhibitory effect on HIV-1 can also be effectively observed in the HeLa cells. In addition, it has also been shown that it can cause apoptosis of human promyelocytic leukaemia via the cytochrome c/caspase-9 pathway.
References
https://www.scbt.com/scbt/product/imperatorin-482-44-0
https://pubchem.ncbi.nlm.nih.gov/compound/imperatorin#section=Top
https://en.wikipedia.org/wiki/Imperatorin
Chemical Properties
White Solid
Uses
Imperatorin (cas# 482-44-0) is a compound useful in organic synthesis.
Definition
ChEBI: A member of the class of psoralens that is psoralen substituted by a prenyloxy group at position 8. Isolated from Angelica dahurica and Angelica koreana, it acts as a acetylcholinesterase inhibitor.
General Description
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Biochem/physiol Actions
Imperatorin is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.
Imperatorin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Lianyungang Kaiyu Environmental Tech Co., Ltd. | +86-0086-19851820538 +8619851820538 | carlos@khonorchem.com | China | 314 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21587 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 4616 | 58 |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | info@konochemical.com | China | 1169 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 1287 | 58 |
| NanJing Spring & Autumn Biological Engineering CO., LTD. | +8613815430202 | sale02@cqherb.com | CHINA | 376 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19936 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
View Lastest Price from Imperatorin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | Imperatorin
482-44-0
|
$41.00-97.00 | 99.52% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-11-04 | Imperatorin
482-44-0
|
$1100.00-1200.00 | 1ton | 99% | 1000 | Lianyungang Kaiyu Environmental Tech Co., Ltd. | |
 |
2023-02-24 | Imperatorin
482-44-0
|
5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. |
-
- Imperatorin
482-44-0
- $41.00-97.00
- 99.52%
- TargetMol Chemicals Inc.
-
- Imperatorin
482-44-0
- $1100.00-1200.00
- 99%
- Lianyungang Kaiyu Environmental Tech Co., Ltd.
-
- Imperatorin
482-44-0
- $0.00
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
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