ChemicalBook >> CAS DataBase List >>5-Amino-2-benzimidazolethiol
5-Amino-2-benzimidazolethiol
- CAS No.
- 2818-66-8
- Chemical Name:
- 5-Amino-2-benzimidazolethiol
- Synonyms
- 5-AMINO-2-MERCAPTOBENZIMIDAZOLE;5-Amino-1H-benzo[d]imidazole-2-thiol;Ilaprazole Intermediate 3;5-aminobenzimidazole-2-thiol;5-AMINO-2-BENZIMIDAZOLETHIOL;2-sulfo-5-amino Benzimidazole;5-AMINO-2-MERCAPTOBENZIMIDAZO;2-mercapto-5-amino benzimidazole;6-Amino-1H-benzimidazole-2-thiol;5-AMINO-1H-BENZIMIDAZOLE-2-THIOL
- CBNumber:
- CB5492178
- Molecular Formula:
- C7H7N3S
- Molecular Weight:
- 165.22
- MDL Number:
- MFCD00022671
- MOL File:
- 2818-66-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-28 03:36:58
| Product description | Number | Pack Size | Price |
| 5-Amino-2-mercaptobenzimidazole 96% | 536067 | 25g | $143 |
| 5-Amino-2-mercaptobenzimidazole >97.0%(T) | A1482 | 5g | $20 |
| 5-Amino-2-mercaptobenzimidazole >97.0%(T) | A1482 | 25g | $61 |
| 5-Amino-2-mercaptobenzimidazole Asreported | 258284 | 10g | $319 |
| 5-Amino-2-mercaptobenzimidazole Asreported | 258284 | 25g | $432 |
| More product size | |||
| Melting point | 240-244 °C (lit.) |
|---|---|
| Boiling point | 356.8±44.0 °C(Predicted) |
| Density | 1.2404 (rough estimate) |
| refractive index | 1.5605 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
| form | powder to crystal |
| pka | 10.44±0.30(Predicted) |
| color | Light yellow to Amber to Dark green |
| Stability | Stable under recommended storage conditions., Stable Under Recommended Storage C |
| InChI | InChI=1S/C7H7N3S/c8-4-1-2-5-6(3-4)10-7(11)9-5/h1-3H,8H2,(H2,9,10,11) |
| InChIKey | BXDMTLVCACMNJO-UHFFFAOYSA-N |
| SMILES | C1(=S)NC2=CC=C(N)C=C2N1 |
| CAS DataBase Reference | 2818-66-8(CAS DataBase Reference) |
| FDA UNII | 98S1PF37NB |
| EPA Substance Registry System | 2H-Benzimidazole-2-thione, 5-amino-1,3-dihydro- (2818-66-8) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 2933998090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
5-Amino-2-benzimidazolethiol price More Price(67)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 536067 | 5-Amino-2-mercaptobenzimidazole 96% | 2818-66-8 | 25g | $143 | 2026-04-30 | Buy |
| TCI Chemical | A1482 | 5-Amino-2-mercaptobenzimidazole >97.0%(T) | 2818-66-8 | 5g | $20 | 2026-04-30 | Buy |
| TCI Chemical | A1482 | 5-Amino-2-mercaptobenzimidazole >97.0%(T) | 2818-66-8 | 25g | $61 | 2026-04-30 | Buy |
| Usbiological | 258284 | 5-Amino-2-mercaptobenzimidazole Asreported | 2818-66-8 | 10g | $319 | 2026-06-03 | Buy |
| Usbiological | 258284 | 5-Amino-2-mercaptobenzimidazole Asreported | 2818-66-8 | 25g | $432 | 2026-06-03 | Buy |
5-Amino-2-benzimidazolethiol Chemical Properties,Uses,Production
Uses
Compounds with a benzimidazole structure, led by omeprazole, can inhibit the acid secretion of gastric parietal cells induced by any stimulus, thus inhibiting the final step of gastric acid being pumped from the parietal cells into the gastric lumen, and therefore have the best therapeutic effect. 5-Amino-2-mercaptobenzimidazole, as an important starting material or intermediate for this type of drug, has a huge market demand.
Chemical Properties
off-white to light yellow crystalline powder
Synthesis
Dissolve 2-mercapto-5-nitrobenzimidazole in methanol, ethanol, dichloromethane, trichloromethane or tetrahydrofuran and add 5-20 equivalents of zinc powder in batches. Concentrated hydrochloric acid is slowly added to the mixture until said mixture is colorless. At the end of the reaction, the insoluble material is removed by filtration, and the filtrate is adjusted to pH=9-10 by adding saturated potassium carbonate solution. activated carbon is added to decolorize the reaction, and the reaction continues to be heated and refluxed for 0.5-2 h. The reaction is filtered through diatomaceous earth, and dried to obtain a yellow solid of 5-amino-2-mercaptobenzimidazole.
5-Amino-2-benzimidazolethiol Preparation Products And Raw materials
Global( 249)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20122 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21587 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 +86-17392581500 | 1015@dideu.com | China | 3991 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
View Lastest Price from 5-Amino-2-benzimidazolethiol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-01 | 5-amino-1,3-dihydrobenzimidazole-2-thione
2818-66-8
|
1KG | 99.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2025-09-25 | 5-Amino-2-benzimidazolethiol
2818-66-8
|
$1.10-34.00 | 1kg | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2021-07-02 | 5-Amino-2-benzimidazolethiol
2818-66-8
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 5-amino-1,3-dihydrobenzimidazole-2-thione
2818-66-8
- 99.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- 5-Amino-2-benzimidazolethiol
2818-66-8
- $1.10-34.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 5-Amino-2-benzimidazolethiol
2818-66-8
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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2818-66-8
C7H7N3S
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