4-Thiazolecarboxylic acid
- CAS No.
- 3973-08-8
- Chemical Name:
- 4-Thiazolecarboxylic acid
- Synonyms
- THIAZOLE-4-CARBOXYLIC ACID;3973/8/8;NSC 195467;AKOS BB-9161;4-CARBOXYTHIAZOLE;TIMTEC-BB SBB010166;4-Carboxy-1,3-thiazole;4-THIAZOLECARBOXYLIC ACID;4-Thiazolecarboxylic acid 97%;1,3-THIAZOLE-4-CARBOXYLIC ACID
- CBNumber:
- CB5769438
- Molecular Formula:
- C4H3NO2S
- Molecular Weight:
- 129.14
- MDL Number:
- MFCD00623589
- MOL File:
- 3973-08-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4-Thiazolecarboxylic acid 97% | 633658 | 1g | $34.4 |
| 4-Thiazolecarboxylic acid 97% | 633658 | 5g | $143 |
| Thiazole-4-carboxylic Acid >98.0%(GC)(T) | T2494 | 1g | $45 |
| Thiazole-4-carboxylic Acid >98.0%(GC)(T) | T2494 | 5g | $156 |
| 1,3-Thiazole-4-carboxylic acid Asreported | 289850 | 10g | $619 |
| More product size | |||
| Melting point | 195-199 °C (lit.) |
|---|---|
| Boiling point | 191 °C |
| Density | 1.525±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 3.57±0.10(Predicted) |
| color | White to Off-White |
| λmax | 230nm(EtOH)(lit.) |
| InChI | InChI=1S/C4H3NO2S/c6-4(7)3-1-8-2-5-3/h1-2H,(H,6,7) |
| InChIKey | HMVYYTRDXNKRBQ-UHFFFAOYSA-N |
| SMILES | S1C=C(C(O)=O)N=C1 |
| CAS DataBase Reference | 3973-08-8(CAS DataBase Reference) |
| FDA UNII | UE1ZOP7MLZ |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H317 | |||||||||
| Precautionary statements | P280 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 43 | |||||||||
| Safety Statements | 36/37 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29341000 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Skin Sens. 1 | |||||||||
| NFPA 704 |
|
4-Thiazolecarboxylic acid price More Price(94)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 633658 | 4-Thiazolecarboxylic acid 97% | 3973-08-8 | 1g | $34.4 | 2026-04-30 | Buy |
| Sigma-Aldrich | 633658 | 4-Thiazolecarboxylic acid 97% | 3973-08-8 | 5g | $143 | 2026-04-30 | Buy |
| TCI Chemical | T2494 | Thiazole-4-carboxylic Acid >98.0%(GC)(T) | 3973-08-8 | 1g | $45 | 2026-04-30 | Buy |
| TCI Chemical | T2494 | Thiazole-4-carboxylic Acid >98.0%(GC)(T) | 3973-08-8 | 5g | $156 | 2026-04-30 | Buy |
| Usbiological | 289850 | 1,3-Thiazole-4-carboxylic acid Asreported | 3973-08-8 | 10g | $619 | 2026-06-03 | Buy |
4-Thiazolecarboxylic acid Chemical Properties,Uses,Production
Chemical Properties
Pale yellow to white solid
Uses
4-Thiazolecarboxylic Acid (cas# 3973-08-8) is a compound useful in organic synthesis.
Synthesis
693-95-8
3973-08-8
The general procedure for the synthesis of thiazole-4-carboxylic acid from 4-methylthiazole was as follows: 4-methylthiazole (19.8 g, 0.2 mol), 200 mL of water, and potassium permanganate (173.8 g, 1.1 mol) were added to a 500 mL three-necked flask, which was heated to 55 °C with stirring and kept for 22 hours. After completion of the reaction, the reaction mixture was cooled and filtered. The filter cake (mainly composed of manganese dioxide) was washed with hot water at 50°C. The filtrate was adjusted to pH 3 with dilute hydrochloric acid, precipitated as a solid and filtered. The filter cake was washed with a small amount of water and dried to give 18.1 g of thiazole-4-carboxylic acid in 70.2% yield, melting point 196-198 °C.
References
[1] Angewandte Chemie, 1992, vol. 104, # 6, p. 748 - 749
[2] Patent: CN104557902, 2018, B. Location in patent: Paragraph 0063; 0076; 0081; 0088; 0089; 0102
4-Thiazolecarboxylic acid Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Chembon Pharmaceutical Co., Ltd. | +86-28-8425-2981 | CHINA | 722 | 55 | |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Klong Industrial Co., Ltd | 0086-519-68231162 | info@klongchem.com | CHINA | 131 | 58 |
| Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 965 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
View Lastest Price from 4-Thiazolecarboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-03-20 | 4-Thiazolecarboxylic acid
3973-08-8
|
$9.90 | 100KG | 99% | 100 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2026-02-02 | 4-Thiazolecarboxylic acid
3973-08-8
|
1g | 99% | 2000tons | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2024-04-22 | 4-Thiazolecarboxylic acid
3973-08-8
|
$1.00 | 1KG | 99.91% | 200000 | Ouhuang Engineering Materials (Hubei) Co., Ltd |
-
- 4-Thiazolecarboxylic acid
3973-08-8
- $9.90
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 4-Thiazolecarboxylic acid
3973-08-8
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- 4-Thiazolecarboxylic acid
3973-08-8
- $1.00
- 99.91%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
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