1'-Hydroxybufuralol
- CAS No.
- 57704-16-2
- Chemical Name:
- 1'-Hydroxybufuralol
- Synonyms
- 1’-Hydroxy Bufuralol (Mixture of Diastereomers);Ro 03-7410;1'-Hydroxybufuralol;1'-Hydroxy bufuralol;1'-hydroxy Bufuralol (Ro 03-7410);Bufuralol Impurity 3(Mixture of Diastereomers);1'-Hydroxy Bufuralol (Mixture of Diastereomers);α2-[[(1,1-DiMethylethyl)aMino]Methyl]-α7-Methyl-;Bufuralol Impurity 3-d9(Mixture of Diastereomers);2-(tert-Butylamino)-1-[7-(1-hydroxyethyl)-1-benzofuran-2-yl]ethanol
- CBNumber:
- CB61356399
- Molecular Formula:
- C16H23NO3
- Molecular Weight:
- 277.36
- MDL Number:
- MFCD04973611
- MOL File:
- 57704-16-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 1''-hydroxy Bufuralol ≥97% | 22160 | 500μg | $208 |
| 1''-hydroxy Bufuralol ≥97% | 22160 | 1mg | $395 |
| 1'-hydroxy Bufuralol ≥97% | 22160 | 500μg | $189 |
| 1'-hydroxy Bufuralol ≥97% | 22160 | 1mg | $359 |
| 1’-Hydroxybufuralol (Mixture of Diastereomers) ~98% | H9038-12 | 1mg | $502 |
| More product size | |||
| Melting point | 41-49°C |
|---|---|
| Boiling point | 433.0±40.0 °C(Predicted) |
| Density | 1.139±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated) |
| form | Solid |
| pka | 13.58±0.20(Predicted) |
| color | Off-White to Beige |
| Stability | Hygroscopic |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| NFPA 704 |
|
1'-Hydroxybufuralol price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 22160 | 1''-hydroxy Bufuralol ≥97% | 57704-16-2 | 500μg | $208 | 2026-04-30 | Buy |
| Cayman Chemical | 22160 | 1''-hydroxy Bufuralol ≥97% | 57704-16-2 | 1mg | $395 | 2026-04-30 | Buy |
| Cayman Chemical | 22160 | 1'-hydroxy Bufuralol ≥97% | 57704-16-2 | 500μg | $189 | 2024-03-01 | Buy |
| Cayman Chemical | 22160 | 1'-hydroxy Bufuralol ≥97% | 57704-16-2 | 1mg | $359 | 2024-03-01 | Buy |
| Usbiological | H9038-12 | 1’-Hydroxybufuralol (Mixture of Diastereomers) ~98% | 57704-16-2 | 1mg | $502 | 2026-06-03 | Buy |
1'-Hydroxybufuralol Chemical Properties,Uses,Production
Description
1’-hydroxy Bufuralol is a metabolite of bufuralol . Bufuralol is metabolized by the cytochrome P450 isoforms 2D1 and 2D2 (CYP2D1/2); therefore, quantification of the bufuralol metabolite, 1’-hydroxy bufuralol, can be used to determine CYP2D1/2 enzyme activity in humans and rats.
Chemical Properties
White to Off-White Solid
Uses
A metabolite of Bufuralol, a β-Adrenergic blocker with peripheral vasodilating activity.
IC 50
CYP2
References
[1] EVANGELOS P DASKALOPOULOS. D-dopaminergic receptor-linked pathways: critical regulators of CYP3A, CYP2C, and CYP2D.[J]. Molecular Pharmacology, 2012, 82 4: 668-678. DOI: 10.1124/mol.112.078709
[2] H YAMAZAKI. Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomes.[J]. Molecular Pharmacology, 1994, 46 3: 568-577.
1'-Hydroxybufuralol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19853 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53803 | 58 |
| LGC Science (Shanghai) Ltd. | 17717235263 | offer.de@lgcgroup.com | China | 18798 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15838 | 69 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32321 | 50 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 | shenlinxing@macklin.cn | China | 15781 | 55 |
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