ChemicalBook >> CAS DataBase List >>CU-CPT-8m
CU-CPT-8m
- CAS No.
- 125079-83-6
- Chemical Name:
- CU-CPT-8m
- Synonyms
- CPD1578;CU-CPT-8m;cas 125079-83-6;CU-CPT-8m ，S4461;CU-CPT-8m, 10 mM in DMSO;TLR8-specific antagonist;CU-CPT-8M;CAS 125079-83-6 ;TLR8 INHIBITOR;7-(m-tolyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;7-(3-methylphenyl) pyrazolo [1,5-a] pyrimidine-3-carboxamide;CU CPT 8m,inhibit,Toll-like Receptor (TLR),CUCPT8m,Inhibitor
- CBNumber:
- CB63369601
- Molecular Formula:
- C14H12N4O
- Molecular Weight:
- 252.27
- MDL Number:
- MFCD31692371
- MOL File:
- 125079-83-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-07-27 17:00:41
| Product description | Number | Pack Size | Price |
| CU-CPT8m ≥98% | 25349 | 1mg | $36 |
| CU-CPT8m ≥98% | 25349 | 5mg | $153 |
| CU-CPT8m ≥98% | 25349 | 10mg | $268 |
| CU-CPT8m ≥98% | 25349 | 25mg | $587 |
| CU-CPT8m ≥98% | 25349 | 1mg | $32 |
| More product size | |||
| Density | 1.35±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform: 5 mg/ml; DMF: 0.2 mg/ml; DMSO: 0.2 mg/ml; Ethanol: slightly soluble |
| form | A crystalline solid |
| pka | 12.41±0.50(Predicted) |
| color | White to off-white |
| InChI | InChI=1S/C14H12N4O/c1-9-3-2-4-10(7-9)12-5-6-16-14-11(13(15)19)8-17-18(12)14/h2-8H,1H3,(H2,15,19) |
| InChIKey | HNKGGVGQAVODNJ-UHFFFAOYSA-N |
| SMILES | C12=C(C(N)=O)C=NN1C(C1=CC=CC(C)=C1)=CC=N2 |
CU-CPT-8m price More Price(58)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 25349 | CU-CPT8m ≥98% | 125079-83-6 | 1mg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 25349 | CU-CPT8m ≥98% | 125079-83-6 | 5mg | $153 | 2026-04-30 | Buy |
| Cayman Chemical | 25349 | CU-CPT8m ≥98% | 125079-83-6 | 10mg | $268 | 2026-04-30 | Buy |
| Cayman Chemical | 25349 | CU-CPT8m ≥98% | 125079-83-6 | 25mg | $587 | 2026-04-30 | Buy |
| Cayman Chemical | 25349 | CU-CPT8m ≥98% | 125079-83-6 | 1mg | $32 | 2024-03-01 | Buy |
CU-CPT-8m Chemical Properties,Uses,Production
Uses
CU-CPT-8m is a specific TLR8 antagonist, with an IC50 of 67 nM.
IC 50
TLR8: 67 nM (IC50)
References
[1] Zhang S, et al. Small-molecule inhibition of TLR8 through stabilization of its resting state. Nat Chem Biol. 2018 Jan;14(1):58-64. DOI:10.1038/nchembio.2518
CU-CPT-8m Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 74)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | +86-18341751992 +86-15382112998 | 757984502@qq.com | China | 892 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32468 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19853 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +86-18051384581 | sales@chemhifuture.com | China | 3135 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39037 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +86-18327326525 | masar@topule.com | China | 8467 | 58 |
125079-83-6(CU-CPT-8m)Related Search:
CPD1578
CU-CPT-8m
cas 125079-83-6
CU-CPT-8M;CAS 125079-83-6 ;TLR8 INHIBITOR
TLR8-specific antagonist
7-(m-tolyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
Pyrazolo[1,5-a]pyrimidine-3-carboxamide, 7-(3-methylphenyl)-
CU CPT 8m,inhibit,Toll-like Receptor (TLR),CUCPT8m,Inhibitor
CU-CPT-8m, 10 mM in DMSO
CU-CPT-8m ，S4461
7-(3-methylphenyl) pyrazolo [1,5-a] pyrimidine-3-carboxamide
125079-83-6
