2-Fluoro-4-iodopyridine
- CAS No.
- 22282-70-8
- Chemical Name:
- 2-Fluoro-4-iodopyridine
- Synonyms
- 4-Iodo-2-fluoropyridine;uoro-4-iodopyridine;2-Fluor-4-iodopyridine;2-FLUORO-4-IODOPYRIDINE;Pyridine, 2-fluoro-4-iodo-;2-Fluoro-4-iodopyridine>2-Fluoro-4-iodopyridine AldrichCPR;2-Fluoro-4-iodopyridine ISO 9001：2015 REACH
- CBNumber:
- CB6361327
- Molecular Formula:
- C5H3FIN
- Molecular Weight:
- 222.99
- MDL Number:
- MFCD03092926
- MOL File:
- 22282-70-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2-Fluoro-4-iodopyridine >98.0%(GC) | F0773 | 1g | $53 |
| 2-Fluoro-4-iodopyridine >98.0%(GC) | F0773 | 5g | $205 |
| 2-Fluoro-4-iodopyridine 98+% (GC) ≥98%(GC) | 230327 | 1g | $163 |
| 2-Fluoro-4-iodopyridine 98+% (GC) ≥98%(GC) | 230327 | 5g | $213 |
| 2-Fluoro-4-iodopyridine 98+% (GC) ≥98%(GC) | 230327 | 25g | $453 |
| More product size | |||
| Melting point | 57 °C |
|---|---|
| Boiling point | 223.0±20.0 °C(Predicted) |
| Density | 2.046±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | -1.81±0.10(Predicted) |
| color | White to Light yellow |
| Sensitive | Light Sensitive |
| InChI | InChI=1S/C5H3FIN/c6-5-3-4(7)1-2-8-5/h1-3H |
| InChIKey | ADPRIAVYIGHFSO-UHFFFAOYSA-N |
| SMILES | C1(F)=NC=CC(I)=C1 |
| CAS DataBase Reference | 22282-70-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H315-H319 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22-36/37/38-22 | |||||||||
| Safety Statements | 22-26-36/37/39 | |||||||||
| Hazard Note | Harmful | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933399990 | |||||||||
| NFPA 704 |
|
2-Fluoro-4-iodopyridine price More Price(65)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | F0773 | 2-Fluoro-4-iodopyridine >98.0%(GC) | 22282-70-8 | 1g | $53 | 2026-04-30 | Buy |
| TCI Chemical | F0773 | 2-Fluoro-4-iodopyridine >98.0%(GC) | 22282-70-8 | 5g | $205 | 2026-04-30 | Buy |
| Usbiological | 230327 | 2-Fluoro-4-iodopyridine 98+% (GC) ≥98%(GC) | 22282-70-8 | 1g | $163 | 2026-06-03 | Buy |
| Usbiological | 230327 | 2-Fluoro-4-iodopyridine 98+% (GC) ≥98%(GC) | 22282-70-8 | 5g | $213 | 2026-06-03 | Buy |
| Usbiological | 230327 | 2-Fluoro-4-iodopyridine 98+% (GC) ≥98%(GC) | 22282-70-8 | 25g | $453 | 2026-06-03 | Buy |
2-Fluoro-4-iodopyridine Chemical Properties,Uses,Production
Chemical Properties
Salmon-coloured solid
Synthesis
113975-22-7
22282-70-8
The general procedure for the synthesis of 2-fluoro-4-iodopyridine from 2-fluoro-3-iodopyridine was as follows: to a solution of 2-fluoro-3-iodopyridine (4.0 g, 17.9 mmol) in anhydrous THF (50 mL) was added slowly and dropwise to LDA (8.96 mL, 2 M THF solution, 17.9 mmol) at -78°C. After the reaction mixture was stirred at -78°C for 4 h, a THF (1 mL) solution of H2O (0.5 mL) was added. Subsequently, the reaction mixture was slowly warmed to room temperature and quenched by the addition of brine (30 mL). The organic layer was separated, washed with brine, dried over anhydrous Na2SO4 and concentrated to give the crude product. The crude product was purified by column chromatography to give 2-fluoro-4-iodopyridine (3.5 g, yield: 87.5%) as a white solid.LC/MS analysis showed m/z (M++H)=224.
References
[1] Organic and Biomolecular Chemistry, 2006, vol. 4, # 10, p. 1927 - 1948
[2] Journal of Organic Chemistry, 1993, vol. 58, # 27, p. 7832 - 7838
[3] Patent: WO2004/76424, 2004, A1. Location in patent: Page 85
[4] Patent: EP1559320, 2005, A1. Location in patent: Page/Page column 6
[5] Patent: WO2013/6792, 2013, A1. Location in patent: Paragraph 0189
2-Fluoro-4-iodopyridine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20111 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 877 | 50 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14032 | 58 |
| Hi-Tech Chemistry Corp | 0519-86626038 | yuhh@hitechem.com | CHINA | 809 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21531 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32998 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2949 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 +86-18019713315 | info@accelachem.com | United States | 21189 | 58 |
View Lastest Price from 2-Fluoro-4-iodopyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-06 | 2-Fluoro-4-iodopyridine
22282-70-8
|
$1.00-200.00 | 1KG | 99%, 99.5% Sublimated | Henan Fengda Chemical Co., Ltd | ||
 |
2026-08-03 | 2-Fluoro-4-iodopyridine
22282-70-8
|
1G | 98% | 2000 | Shenzhen Nexcon Pharmatechs Ltd. | ||
 |
2026-08-03 | 2-Fluoro-4-iodopyridine
22282-70-8
|
1G | 98% | 2000 | Shenzhen Nexcon Pharmatechs Ltd. |
-
- 2-Fluoro-4-iodopyridine
22282-70-8
- $1.00-200.00
- 99%, 99.5% Sublimated
- Henan Fengda Chemical Co., Ltd
-
- 2-Fluoro-4-iodopyridine
22282-70-8
- $0.00
- 98%
- Shenzhen Nexcon Pharmatechs Ltd.
-
- 2-Fluoro-4-iodopyridine
22282-70-8
- $0.00
- 98%
- Shenzhen Nexcon Pharmatechs Ltd.
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