10-Gingerol
- CAS No.
- 23513-15-7
- Chemical Name:
- 10-Gingerol
- Synonyms
- (s)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-tetradecanone;10-GINGEROL;GINGEROL, 10-;10-Gingerol ,98%;10-GINGEROL, HPLC 98%;(+)-(S)-[10]-Gingerol;10-Gingerol USP/EP/BP;[10]-Gingerol Standard;10]-Gingerol >=95% (HPLC);Propionic Acid Impurity 1
- CBNumber:
- CB6399377
- Molecular Formula:
- C21H34O4
- Molecular Weight:
- 350.49
- MDL Number:
- MFCD01682694
- MOL File:
- 23513-15-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| [10]-Gingerol ≥95% (HPLC) | G5798 | 5mg | $340 |
| [10]-Gingerol analytical standard | 42630 | 10mg | $813 |
| 10-Gingerol ≥98% | 11842 | 1mg | $42 |
| 10-Gingerol ≥98% | 11842 | 5mg | $183 |
| 10-Gingerol ≥98% | 11842 | 10mg | $322 |
| More product size | |||
| Melting point | 56-58 °C |
|---|---|
| Boiling point | 499.7±35.0 °C(Predicted) |
| Density | 1.037±0.06 g/cm3(Predicted) |
| Flash point | 166℃ |
| storage temp. | 2-8°C |
| solubility | methanol: soluble5mg/mL, clear, colorless |
| form | Solid |
| pka | 10.02±0.20(Predicted) |
| color | Yellow |
| Water Solubility | practically insoluble in water |
| Major Application |
metabolomics vitamins, nutraceuticals, and natural products |
| InChI | InChI=1S/C21H34O4/c1-3-4-5-6-7-8-9-10-18(22)16-19(23)13-11-17-12-14-20(24)21(15-17)25-2/h12,14-15,18,22,24H,3-11,13,16H2,1-2H3/t18-/m0/s1 |
| InChIKey | AIULWNKTYPZYAN-SFHVURJKSA-N |
| SMILES | C(C1=CC=C(O)C(OC)=C1)CC(=O)C[C@@H](O)CCCCCCCCC |
| LogP | 4.900 (est) |
| FDA UNII | ND6ZLI4J0V |
| UNSPSC Code | 85151701 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| target organs | Respiratory system |
| Risk Statements | 53 |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| HS Code | 29145019 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
10-Gingerol price More Price(82)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | G5798 | [10]-Gingerol ≥95% (HPLC) | 23513-15-7 | 5mg | $340 | 2026-04-30 | Buy |
| Sigma-Aldrich | 42630 | [10]-Gingerol analytical standard | 23513-15-7 | 10mg | $813 | 2026-04-30 | Buy |
| Cayman Chemical | 11842 | 10-Gingerol ≥98% | 23513-15-7 | 1mg | $42 | 2026-04-30 | Buy |
| Cayman Chemical | 11842 | 10-Gingerol ≥98% | 23513-15-7 | 5mg | $183 | 2026-04-30 | Buy |
| Cayman Chemical | 11842 | 10-Gingerol ≥98% | 23513-15-7 | 10mg | $322 | 2026-04-30 | Buy |
10-Gingerol Chemical Properties,Uses,Production
Description
10-Gingerol is a phenol that has been found in Z. officinale and has diverse biological activities. It scavenges DPPH , superoxide, and hydroxyl radicals in cell-free assays (IC50s = 10.47, 1.68, and 1.35 μM, respectively) and inhibits oxidative burst induced by N-formyl-Met-Leu-Phe (fMLP; ) in isolated human polymorphonuclear (PMN) neutrophils when used at a concentration of 6 μM. 10-Gingerol inhibits NETosis and the production of reactive oxygen species (ROS) induced by LPS or lupus-relevant stimuli, including ribonucleoprotein-containing immune complexes and anti-phospholipid antibodies, in isolated human neutrophils. It is active against M. avium and M. tuberculosis (MICs = 25 and 50 μg/ml, respectively). 10-Gingerol (200 μM) is also cytotoxic to human MDA-MB-231 and MDA-MB-468 and murine 4T1 and EO771 mammary carcinoma cells.
Chemical Properties
White waxy, soluble in methanol, ethanol, DMSO and other organic solvents, derived from ginger.
Uses
(+)-(S)-[10]-Gingerol has been observed to exhibit anti-oxidant behaviour towards lipids and is effective in suppressing obesity and adipose tissue inflammation.
Definition
ChEBI: (10)-Gingerol is a beta-hydroxy ketone, a member of phenols and a monomethoxybenzene.
Biochem/physiol Actions
[10]-Gingerol is a bioactive compound found in ginger (Zingiber officinale) with anti-inflammatory and antioxidant activity.
in vivo
10-Gingerol (30 mg/kg, i.p., 7 consecutive days) reverses body weight loss, declines disease activity index (DAI), decreasing myeloperoxidase (MPO) activity and malondialdehyde (MDA) level, as well as restoring SOD activity, reduces the serum TNF-α and IL-1β levels, ameliorates mucosa inflammation and/or defect in rats with DSS-induced acute ulcerative colitis[4].
| Animal Model: | Rats with DSS-induced acute ulcerative colitis[4] |
| Dosage: | 30 mg/kg |
| Administration: | i.p., 7 consecutive days |
| Result: | Reversed body weight loss and significantly declined DAI, reduced the serum TNF-α and IL-1β levels, ameliorated mucosa inflammation and/or defect in rats with DSS-induced acute ulcerative colitis in rats with DSS-induced acute ulcerative colitis. |
References
[1] SWARNALATHA DUGASANI . Comparative antioxidant and anti-inflammatory effects of [6]-gingerol, [8]-gingerol, [10]-gingerol and [6]-shogaol[J]. Journal of ethnopharmacology, 2010, 127 2: Pages 515-520. DOI: 10.1016/j.jep.2009.10.004
[2] RAMADAN A ALI. Antineutrophil properties of natural gingerols in models of lupus.[J]. JCI insight, 2021. DOI: 10.1172/jci.insight.138385
[3] R. D. HISERODT R. T R S G Franzblau. Isolation of 6-, 8-, and 10-Gingerol from Ginger Rhizome by HPLC and Preliminary Evaluation of Inhibition of Mycobacterium avium and Mycobacterium tuberculosis[J]. Journal of Agricultural and Food Chemistry, 1998, 46 7: 2504-2508. DOI: 10.1021/jf970948l
[4] MEGAN M. BERNARD David W H Jason R McConnery. [10]-Gingerol, a major phenolic constituent of ginger root, induces cell cycle arrest and apoptosis in triple-negative breast cancer cells[J]. Experimental and molecular pathology, 2017, 102 2: Pages 370-376. DOI: 10.1016/j.yexmp.2017.03.006
10-Gingerol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Danding Pharmaceutical Technology Co., Ltd | +86-18917019315 +86-13173601896 | 3582572959@qq.com | China | 496 | 58 |
| Lianyungang Kaiyu Environmental Tech Co., Ltd. | +86-0086-19851820538 +8619851820538 | carlos@khonorchem.com | China | 314 | 58 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 4616 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | 52513593@qq.com | CHINA | 2972 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
View Lastest Price from 10-Gingerol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-24 | 10-Gingerol
23513-15-7
|
20MG | ≥98%HPLC | Changsha Staherb Natural Ingredients Co., Ltd. | |||
 |
2026-07-15 | 10-Gingerol
23513-15-7
|
$34.00-98.00 | 99.61% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-06-30 | 10-Gingerol
23513-15-7
|
1KG | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd |
-
- 10-Gingerol
23513-15-7
- $0.00
- ≥98%HPLC
- Changsha Staherb Natural Ingredients Co., Ltd.
-
- 10-Gingerol
23513-15-7
- $34.00-98.00
- 99.61%
- TargetMol Chemicals Inc.
-
- 10-Gingerol
23513-15-7
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
