5-BROMO-2-METHYLPYRIDIN-3-AMINE
- CAS No.
- 914358-73-9
- Chemical Name:
- 5-BROMO-2-METHYLPYRIDIN-3-AMINE
- Synonyms
- 3-Amino-5-bromo-2-methylpyridine;3-Amino-5-bromopicoline;3-Amino-5-bromo-2-methylp...;5-bromo-2-methyl-3-Pyridinamine;5-BROMO-2-METHYLPYRIDIN-3-AMINE;3-Amin-5-bromo-2-methylpyridine;5-Bromo-2-Methylpyridine-3-amine;2-Methyl-3-amino-5-bromopyridine;3-pyridinaMine, 5-broMo-2-Methyl;5-BroMo-2-Methyl-pyridin-3-ylaMine
- CBNumber:
- CB6818821
- Molecular Formula:
- C6H7BrN2
- Molecular Weight:
- 187.04
- MDL Number:
- MFCD09031418
- MOL File:
- 914358-73-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 3-Amino-5-bromo-2-methylpyridine Asreported | 261282 | 500mg | $355 |
| 3-Amino-5-bromo-2-methylpyridine Asreported | 261282 | 1g | $615 |
| 3-Amino-5-bromo-2-methylpyridine Asreported | 261282 | 2g | $864 |
| 3-Amino-5-bromo-2-methylpyridine Asreported | 261282 | 5g | $1218 |
| 5-BROMO-2-METHYLPYRIDIN-3-AMINE 97% | 51734 | 5G | $58 |
| More product size | |||
| Melting point | 108-109℃ |
|---|---|
| Boiling point | 283.5±35.0 °C(Predicted) |
| Density | 1.593±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| form | crystalline solid |
| pka | 4.53±0.20(Predicted) |
| color | Off-white |
| InChI | InChI=1S/C6H7BrN2/c1-4-6(8)2-5(7)3-9-4/h2-3H,8H2,1H3 |
| InChIKey | CBAXYISWNGGXOZ-UHFFFAOYSA-N |
| SMILES | C1(C)=NC=C(Br)C=C1N |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H315-H319-H335-H302-H318 | |||||||||
| Precautionary statements | P280-P305+P351+P338-P261-P280a-P304+P340-P405-P501a | |||||||||
| Risk Statements | 41 | |||||||||
| Safety Statements | 26-39 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933399990 | |||||||||
| NFPA 704 |
|
5-BROMO-2-METHYLPYRIDIN-3-AMINE price More Price(73)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 261282 | 3-Amino-5-bromo-2-methylpyridine Asreported | 914358-73-9 | 500mg | $355 | 2026-06-03 | Buy |
| Usbiological | 261282 | 3-Amino-5-bromo-2-methylpyridine Asreported | 914358-73-9 | 1g | $615 | 2026-06-03 | Buy |
| Usbiological | 261282 | 3-Amino-5-bromo-2-methylpyridine Asreported | 914358-73-9 | 2g | $864 | 2026-06-03 | Buy |
| Usbiological | 261282 | 3-Amino-5-bromo-2-methylpyridine Asreported | 914358-73-9 | 5g | $1218 | 2026-06-03 | Buy |
| AstaTech | 51734 | 5-BROMO-2-METHYLPYRIDIN-3-AMINE 97% | 914358-73-9 | 5G | $58 | 2026-04-30 | Buy |
5-BROMO-2-METHYLPYRIDIN-3-AMINE Chemical Properties,Uses,Production
Description
5-Bromo-2-methylpyridin-3-amine is also named as 3-Amino-5-bromo-2-methylpyridine. It can be converted to 5-bromo-2-methyl-3-pyridinol by diazotization with sodium nitrite in aqueous sulfuric acid. 5-Bromo-2-methyl-3-pyridinol can be used to make brominated dihydropyridines, which are substrates for the palladium catalyzed coupling, a process to produce compounds for the treatment of patients with disorders, such as central nervous system disorders.
Reference
G. Dull, J. Munoz, J. Genus, J. Moore, Hydroxybenzoate salts of metanicotine compounds, Patent US20060122239A1
Uses
3-Amino-5-bromo-2-methylpyridine (3ABMP) is a kind of biochemical reagent.
Synthesis
911434-05-4
914358-73-9
The general procedure for the synthesis of 2-methyl-3-amino-5-bromopyridine from 5-bromo-2-methyl-3-nitropyridine was as follows: 5-bromo-2-methyl-3-nitropyridine (13.8 g, 63.9 mmol) was dissolved in industrial methanol (330 mL) at 40 °C, followed by the addition of powdered iron (20 g) in batches to avoid agglomeration. Next, concentrated aqueous hydrochloric acid (5 mL) was added for elution. The resulting dark brown mixture was stirred vigorously under reflux conditions for 2 h. After completion of the reaction, it was cooled to room temperature and filtered through Celite (the filter cake was washed with 1 L of industrial methanol). The filtrate was concentrated under reduced pressure to remove the solvent, and the residue was dissolved in ethyl acetate (200 mL), the organic phase was washed with saturated aqueous sodium bicarbonate (200 mL), and dried with anhydrous magnesium sulfate. Finally, the solvent was removed under reduced pressure to afford the target product 5-bromo-2-methylpyridin-3-amine as an orange solid (10.7 g, 90% yield). The structure of the product was confirmed by 1HNMR (400 MHz, CDCl3, δ): 7.91 (s, 1H), 7.00 (s, 1H), 3.75 (br.s, 2H), 2.25 (s, 3H).
References
[1] Bergmeyer, et al. "Biochemical reagents." Methods of Enzymatic Analysis. Academic Press, 1965. 967-1037.
5-BROMO-2-METHYLPYRIDIN-3-AMINE Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20120 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14026 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29792 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-173 9270 1263 | 1057@dideu.com | China | 3957 | 58 |
View Lastest Price from 5-BROMO-2-METHYLPYRIDIN-3-AMINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-09 | 5-BROMO-2-METHYLPYRIDIN-3-AMINE
914358-73-9
|
$6.00 | 1KG | 98% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-06-30 | 5-BROMO-2-METHYLPYRIDIN-3-AMINE
914358-73-9
|
1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2021-07-13 | 5-BROMO-2-METHYLPYRIDIN-3-AMINE
914358-73-9
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 5-BROMO-2-METHYLPYRIDIN-3-AMINE
914358-73-9
- $6.00
- 98%
- Henan Fengda Chemical Co., Ltd
-
- 5-BROMO-2-METHYLPYRIDIN-3-AMINE
914358-73-9
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- 5-BROMO-2-METHYLPYRIDIN-3-AMINE
914358-73-9
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
914358-73-9(5-BROMO-2-METHYLPYRIDIN-3-AMINE)Related Search:
1of4
