5-Bromo-2-methylpyridine
- CAS No.
- 3430-13-5
- Chemical Name:
- 5-Bromo-2-methylpyridine
- Synonyms
- 5-BROMO-2-PICOLINE;5-BROMOPICOLINE;3-BROMO-6-PICOLINE;2-Methyl-5-bromopyrid;5-Bromo-2-picoline,99%;5-BROMO-2-METHYLPYRIDINE;3-BROMO-6-METHYLPYRIDINE;2-METHYL-5-BROMOPYRIDINE;5-broMo-1-Methylpyridine;5-bormo-2-methylpyridine
- CBNumber:
- CB7327298
- Molecular Formula:
- C6H6BrN
- Molecular Weight:
- 172.02
- MDL Number:
- MFCD00661170
- MOL File:
- 3430-13-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 5-Bromo-2-methylpyridine >98.0%(GC) | B2572 | 1g | $19 |
| 5-Bromo-2-methylpyridine >98.0%(GC) | B2572 | 5g | $49 |
| 5-Bromo-2-methylpyridine Asreported | 262091 | 10g | $389 |
| 5-Bromo-2-methylpyridine Asreported | 262091 | 25g | $549 |
| 5-Bromo-2-methylpyridine Asreported | 262091 | 50g | $744 |
| More product size | |||
| Melting point | 32-36 °C |
|---|---|
| Boiling point | 74 °C / 17mmHg |
| Density | 1.494±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| form | Solid |
| pka | 3.59±0.10(Predicted) |
| color | Off-White to Light Yellow |
| BRN | 107324 |
| InChI | InChI=1S/C6H6BrN/c1-5-2-3-6(7)4-8-5/h2-4H,1H3 |
| InChIKey | OFKWIQJLYCKDNY-UHFFFAOYSA-N |
| SMILES | C1(C)=NC=C(Br)C=C1 |
| CAS DataBase Reference | 3430-13-5(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS06 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335-H301-H311-H332 | |||||||||
| Precautionary statements | P261-P305+P351+P338-P301+P310a-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36-36/37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29333990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
5-Bromo-2-methylpyridine price More Price(85)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | B2572 | 5-Bromo-2-methylpyridine >98.0%(GC) | 3430-13-5 | 1g | $19 | 2026-04-30 | Buy |
| TCI Chemical | B2572 | 5-Bromo-2-methylpyridine >98.0%(GC) | 3430-13-5 | 5g | $49 | 2026-04-30 | Buy |
| Usbiological | 262091 | 5-Bromo-2-methylpyridine Asreported | 3430-13-5 | 10g | $389 | 2026-06-03 | Buy |
| Usbiological | 262091 | 5-Bromo-2-methylpyridine Asreported | 3430-13-5 | 25g | $549 | 2026-06-03 | Buy |
| Usbiological | 262091 | 5-Bromo-2-methylpyridine Asreported | 3430-13-5 | 50g | $744 | 2026-06-03 | Buy |
5-Bromo-2-methylpyridine Chemical Properties,Uses,Production
Description
It is an important intermediate in the organic synthesis, which has many applications, such as pharmaceutical intermediate, organic synthesis, organic solvent, production of dyes, pesticide, and spice. Specifically, this chemical can act as the raw material to prepare 2:2’-dipyridyl and its derivatives.1 Moreover, this compound may be involved in the synthesis of biaryls through a one-pot tandem borylation/Suzuki-Miyaura cross-coupling reaction catalyzed by a palladacycle.2 In addition, 5-bromo-2-methylpyridine has been demonstrated to function as the substrate in a general palladium-catalyzed coupling of aryl bromides/triflates and thiols.3 Besides, this substance can facilitate the synthesis of 5-arylamino-2-picolines via displacement of bromide by anthranilic acid and decarboxylation.4
Referrence
- Willink, H. D. T.; Wibaut, J. P., The preparation of 2 : 2'-dipyridyl and some of its derivatives. Recueil Des Travaux Chimiques Des Pays-Bas 1935, 54, 275-283.
- Wang, L. H.; Cui, X. L.; Li, J. Y.; Wu, Y. S.; Zhu, Z. W.; Wu, Y. J., Synthesis of Biaryls through a One-Pot Tandem Borylation/Suzuki-Miyaura Cross-Coupling Reaction Catalyzed by a Palladacycle. Eur. J. Org. Chem. 2012, 595-603.
- Itoh, T.; Mase, T., A general palladium-catalyzed coupling of aryl bromides/triflates and thiols. Org. Lett. 2004, 6, 4587-4590.
- Louis H. Peterson; Tolman, R. L., Reinvestigation of the synthesis of 5-arylamino-2-picolines J. Heterocycl. Chem. 1977.
Chemical Properties
Light yellow Cryst
Uses
5-Bromo-2-picoline is a halogenated pyridine derivative used is a building block in the preparation of nitrogen containing heterocyclic compounds.
Synthesis
The synthesis method comprises the following steps: reacting diethyl malonate with alkali metal to generate salts, dripping 5-nitryl-2-chloropyridine into the salts for condensation reaction, and subsequently performing decarboxylation on the obtained product under acidic condition to obtain 5-nitryl-2-methylpyridine; performing hydrogenation reduction on the 5-nitryl-2-methylpyridine under the catalysis of Pd/C catalyst to obtain 5-amido-2-methylpyridine; and reacting the 5-amido-2-methylpyridine with acid to generate salts, dripping bromine, dripping a sodium nitrite water solution, and obtaining the 5-bromo-2-methylpyridine.
5-Bromo-2-methylpyridine Preparation Products And Raw materials
Raw materials
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Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Terma Medicare India Pvt.,Ltd | +86-53530655; +8613916485955 | shivshanghai@yahoo.com | India | 249 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5224 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20121 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21586 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
View Lastest Price from 5-Bromo-2-methylpyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-03 | 5-Bromo-2-methylpyridine
3430-13-5
|
$5.00 | 1KG | 98% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-07-03 | 5-Bromo-2-methylpyridine
3430-13-5
|
1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-06-30 | 5-Bromo-2-methylpyridine
3430-13-5
|
1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd |
-
- 5-Bromo-2-methylpyridine
3430-13-5
- $5.00
- 98%
- Henan Fengda Chemical Co., Ltd
-
- 5-Bromo-2-methylpyridine
3430-13-5
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 5-Bromo-2-methylpyridine
3430-13-5
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
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