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5-Bromo-2-methoxypyridine

5-Bromo-2-methoxypyridine structure

CAS No.: 13472-85-0

Chemical Name:: 5-Bromo-2-methoxypyridine

Synonyms: 5-Bromo-2- Methoxypyidine;2-METHOXY-5-BROMOPYRIDINE;2-Methyloxy-5-bromo;5-Bromo-2-methoxypyr;Perampanel Impurity 10;5-BROMO-2-METHOXYPRIDINE;5-BROMO-2-METHOXYPYRIDINE;5-Bromo-2-methyloxypyridine;PYRIDINE, 5-BROMO-2-METHOXY-;2-Methoxy -5-pyridyl broMide

CBNumber:: CB7706983

Molecular Formula:: C6H6BrNO

Molecular Weight:: 188.02

MDL Number:: MFCD01318952

MOL File:: 13472-85-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 02:48:31

Product description	Number	Pack Size	Price
5-Bromo-2-methoxypyridine 95%	510297	5ml	$78.2
5-Bromo-2-methoxypyridine 95%	510297	25ml	$200
5-Bromo-2-methoxypyridine >98.0%(GC)(T)	B2398	5g	$29
5-Bromo-2-methoxypyridine >98.0%(GC)(T)	B2398	25g	$84
5-BROMO-2-METHOXY-PYRIDINE 95%	54649	10G	$6
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5-Bromo-2-methoxypyridine Properties

Boiling point	80 °C/12 mmHg (lit.)
Density	1.453 g/mL at 25 °C (lit.)
refractive index	n20/D 1.555(lit.)
Flash point	205 °F
storage temp.	Inert atmosphere,Room Temperature
pka	1.04±0.10(Predicted)
form	Liquid
Specific Gravity	1.453
color	Clear colorless to slightly yellow
BRN	115150
InChI	InChI=1S/C6H6BrNO/c1-9-6-3-2-5(7)4-8-6/h2-4H,1H3
InChIKey	XADICJHFELMBGX-UHFFFAOYSA-N
SMILES	C1(OC)=NC=C(Br)C=C1
LogP	0.952
CAS DataBase Reference	13472-85-0(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Codes

Xi,Xn

Risk Statements

36/37/38-20/21/22

Safety Statements

26-36-36/37/39

WGK Germany

HazardClass

IRRITANT

HS Code

29349990

Storage Class

10 - Combustible liquids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

REACH Registrations

Active

NFPA 704

	1
2		0

5-Bromo-2-methoxypyridine price More Price(75)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	510297	5-Bromo-2-methoxypyridine 95%	13472-85-0	5ml	$78.2	2023-06-20	Buy
Sigma-Aldrich	510297	5-Bromo-2-methoxypyridine 95%	13472-85-0	25ml	$200	2023-06-20	Buy
TCI Chemical	B2398	5-Bromo-2-methoxypyridine >98.0%(GC)(T)	13472-85-0	5g	$29	2026-04-30	Buy
TCI Chemical	B2398	5-Bromo-2-methoxypyridine >98.0%(GC)(T)	13472-85-0	25g	$84	2026-04-30	Buy
AstaTech	54649	5-BROMO-2-METHOXY-PYRIDINE 95%	13472-85-0	10G	$6	2026-04-30	Buy

Product number	Packaging	Price	Buy
510297	5ml	$78.2	Buy
510297	25ml	$200	Buy
B2398	5g	$29	Buy
B2398	25g	$84	Buy
54649	10G	$6	Buy

5-Bromo-2-methoxypyridine Chemical Properties,Uses,Production

Chemical Properties

Light yellow liquid

Uses

5-Bromo-2-methoxypyridine is used as a ligand for central nicotinic acetylcholine receptor. Also used in a novel synthetic approach to anti-HIV active integrase inhibitors.

Uses

A building block for the β-alanine moiety of an α_vβ₃ antagonist and for the synthesis of a potent and selective somatostatin sst₃ receptor antagonist.

Synthesis

624-28-2

13472-85-0

Step 1. 2,5-dibromopyridine (5.5 g, 23.2 mmol) and sodium methanolate (3.76 g, 69.6 mmol) were dissolved in methanol (60 mL), and the mixture was placed in a sealed reaction vessel and heated to react for 42 hours at 70 °C. After completion of the reaction, the reaction mixture was cooled to room temperature, diluted with water (50 mL) and extracted with ethyl acetate (2 x 100 mL). The organic layers were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure to give the light yellow oily product 5-bromo-2-methoxypyridine (4.1 g, 95% yield). Thin layer chromatography (TLC) analytical conditions: 10% ethyl acetate/90% hexane, Rf value of 0.57.

References

[1] Patent: US2002/65296, 2002, A1
[2] Patent: US2004/102636, 2004, A1
[3] Patent: EP1042305, 2005, B1. Location in patent: Page/Page column 32-33
[4] Tetrahedron, 1985, vol. 41, # 7, p. 1373 - 1384
[5] Patent: EP1308441, 2003, A1

5-Bromo-2-methoxypyridine synthesis

Synthesis of 5-Bromo-2-methoxypyridine from 2,5-Dibromopyridine and Methanol

5-Bromo-2-methoxypyridine Preparation Products And Raw materials

Raw materials

TETRABUTYLAMMONIUM METHOXIDE 3-Bromo-2-methoxypyridine 2-Hydroxy-5-bromopyridine 5-Bromo-2-chloropyridine 2-METHOXY-3,5-DIBROMO-PYRIDINE

2,5-Dibromopyridine 5-Amino-2-methoxypyridine Methanol 2-Methoxypyridine 5-Bromo-2-nitropyridine

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Preparation Products

2-Methoxy-5-pyridineboronic acid 6-Methoxynicotinaldehyde 2-HYDROXY-5-FORMYLPYRIDINE 5-BROMO-3-CHLORO-2-PYRIDINONE 5-BROMO-3-FLUORO-2-PYRIDINONE

5-BROMO-2-METHOXY-3-NITRO-PYRIDINE 5-Bromo-2-chloropyridine 5-ACETYL-2-METHOXYPYRIDINE, 97% 5-(2-PYRIDYL)-1,2-DIHYDROPYRIDIN-2-ONE

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5-Bromo-2-methoxypyridine Suppliers

Global( 628)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20122	58
Frapp's ChemicalNFTZ Co., Ltd.	+86 (576) 8169-6106	sales@frappschem.com	China	880	50
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
Hi-Tech Chemistry Corp	0519-86626038	yuhh@hitechem.com	CHINA	810	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21587	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Zhejiang ZETian Fine Chemicals Co. LTD	+8618957127338	stella@zetchem.com	China	2994	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10403	58
HaBo Hong Kong Co., Limited.	+86-25-18512596065	info@habotech.com	CHINA	933	58

Supplier	Advantage
Henan Fengda Chemical Co., Ltd	58
Frapp's ChemicalNFTZ Co., Ltd.	50
Capot Chemical Co.,Ltd.	60
Hi-Tech Chemistry Corp	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Zhejiang ZETian Fine Chemicals Co. LTD	58
Shenzhen Nexconn Pharmatechs Ltd	58
HaBo Hong Kong Co., Limited.	58

View Lastest Price from 5-Bromo-2-methoxypyridine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-03-12	Perampanel Impurity 10		10mg	98%	500mg	ShenZhen H&D Pharmaceutical Technology Co., LTD
2025-12-01	5-Bromo-2-methoxypyridine 13472-85-0		1KG	99.0%	10000KGS	Shaanxi Dideu New Materials Co. Ltd
2025-11-18	5-Bromo-2-methoxypyridine 13472-85-0	$1.10	1g	99.00%	100 Tons Min	Dideu Industries Group Limited

Perampanel Impurity 10
98%
ShenZhen H&D Pharmaceutical Technology Co., LTD

5-Bromo-2-methoxypyridine
13472-85-0
99.0%
Shaanxi Dideu New Materials Co. Ltd

5-Bromo-2-methoxypyridine
13472-85-0
$1.10
99.00%
Dideu Industries Group Limited

5-Bromo-2-methoxypyridine Spectrum

5-Bromo-2-methoxypyridine(13472-85-0)¹HNMR 5-Bromo-2-methoxypyridine(13472-85-0)IR

13472-85-0(5-Bromo-2-methoxypyridine)Related Search:

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PeraMpanel 2-bromo-3-(1,3,2-dioxaborinan-2-yl)benzonitrile 6'-Methoxy-2,3'-bipyridine

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2-METHOXY-5-BROMOPYRIDINE 5-BROMO-2-METHOXY-PYRIDINE 5-Bromo-2-methoxypyridine 95% 5-Bromo-2-methoxypyridine ,98% 5-Bromo-2-methoxypyridine,97% 5-BroMo-2-Methoxypyridine, 97% 5ML (E)-N-(pyridin-3-ylmethylene)methanamine 5-Bromo-2-methoxypyr 2-Methoxy -5-pyridyl broMide 2 - Methoxy - 5 - broMide pyridine 5-2 - Methoxy pyridine broMide - PYRIDINE, 5-BROMO-2-METHOXY- 5-BROMO-2-METHOXYPYRIDINE 5-BROMO-2-METHOXYPRIDINE 5-Bromo-2-methoxypyridine > Perampanel Impurity 10 5-Bromo-2-methoxypyridine ISO 9001：2015 REACH 5-Bromo-2-methyloxypyridine "5 - bromine - 2 - a Oxygen radicals pyridine (pyrazole shimron Nai impurities A - 2)" 5-Bromo-2- Methoxypyidine 2-Methyloxy-5-bromo 2-METHOXY-5-BROMOPYRIDINE 13472-85-0 Bromopyridines Halopyridines Halogenated Heterocycles Heterocyclic Building Blocks Pyridines Building Blocks alkyl bromide Brominated heterocyclic series Halopyridines Boronic Acid C6Heterocyclic Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks compounds of pyridine Alkoxy Organohalides Pyridines derivates Pyridine Series Pyridines, Pyrimidines, Purines and Pteredines Anisoles, Alkyloxy Compounds & Phenylacetates Bromine Compounds Miscellaneous Compounds Bromopyridines blocks Bromides Pyridines Pyridine pyridine derivative

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5-Bromo-2-methoxypyridine

5-Bromo-2-methoxypyridine Properties

SAFETY

Risk and Safety Statements

5-Bromo-2-methoxypyridine price More Price(75)

5-Bromo-2-methoxypyridine Chemical Properties,Uses,Production

Chemical Properties

Uses

Uses

Synthesis

References

5-Bromo-2-methoxypyridine synthesis

5-Bromo-2-methoxypyridine Preparation Products And Raw materials

Raw materials

Preparation Products

5-Bromo-2-methoxypyridine Suppliers

View Lastest Price from 5-Bromo-2-methoxypyridine manufacturers

5-Bromo-2-methoxypyridine Spectrum

13472-85-0(5-Bromo-2-methoxypyridine)Related Search: