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ChemicalBook >> CAS DataBase List >>Tandospirone citrate

Tandospirone citrate

CAS No.
112457-95-1
Chemical Name:
Tandospirone citrate
Synonyms
andospironecitrate;SM 3997;Methanospirone;SM-3997 citrate;tandospirone citrate;Tandopsirone citrate;Tandospirone-d8 Citrate;Tandospirone citrate (SM 3997);2-(Dicyclohexylphosphanyl)-1-(2-methoxy-6-(triethylsilyl)phenyl)-1H-pyrrole;(3aR,4R,7S,7aS)-2-(4-chlorobutyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
CBNumber:
CB71270043
Molecular Formula:
C21H29N5O2.C6H8O7
Molecular Weight:
575.61
MDL Number:
MOL File:
112457-95-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41
Product description Number Pack Size Price
Tandospirone citrate 99.92% CS-4598 5mg $65
Tandospirone citrate 99.92% CS-4598 10mg $103
Tandospirone citrate 99.92% CS-4598 25mg $206
Tandospirone citrate 99.92% CS-4598 50mg $325
Tandospirone citrate 99.92% CS-4598 100mg $520
More product size

Tandospirone citrate Properties

Melting point 169.5-170°
storage temp. Inert atmosphere,Store in freezer, under -20°C
form Solid
color White to off-white
Water Solubility Water: 10.4 mg/mL (18.07 mM)
InChIKey DMLGUJHNIWGCKM-DPFKZJTMNA-N
SMILES [C@@]12(C(=O)N(CCCCN3CCN(C4=NC=CC=N4)CC3)C(=O)[C@]1([C@@]1(CC[C@]2(C1)[H])[H])[H])[H].C(O)(C(=O)O)(CC(=O)O)CC(=O)O |&1:0,22,23,26,r|
FDA UNII 0R8E9BWM4J

Tandospirone citrate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-4598 Tandospirone citrate 99.92% 112457-95-1 5mg $65 2026-06-04 Buy
ChemScene CS-4598 Tandospirone citrate 99.92% 112457-95-1 10mg $103 2026-06-04 Buy
ChemScene CS-4598 Tandospirone citrate 99.92% 112457-95-1 25mg $206 2026-06-04 Buy
ChemScene CS-4598 Tandospirone citrate 99.92% 112457-95-1 50mg $325 2026-06-04 Buy
ChemScene CS-4598 Tandospirone citrate 99.92% 112457-95-1 100mg $520 2026-06-04 Buy
Product number Packaging Price Buy
CS-4598 5mg $65 Buy
CS-4598 10mg $103 Buy
CS-4598 25mg $206 Buy
CS-4598 50mg $325 Buy
CS-4598 100mg $520 Buy

Tandospirone citrate Chemical Properties,Uses,Production

Physical Form

solid

Uses

Tandospirone citrate is a potent 5-HT1A partial agonist with a Ki value of 27 nM. Tandospirone citrate is approximately two to three orders of magnitude less potent at 5-HT2, 5-HT1C, alpha 1-adrenergic, alpha 2-adrenergic, and dopamine D1 and D2 receptors (Ki values ranging from 1300 to 41000 nM).
Anti-anxiety agent.

Definition

ChEBI: Tandospirone citrate is a citrate salt of tandospirone , comprising equimolar amounts of citric acid and tandospirone. It is an anxiolytic drug used in the treatment of anxiety disorders. It has a role as an anxiolytic drug and an antidepressant. It contains a tandospirone(1+).

Pharmacology

Tandospirone citrate is a partial agonist of the 5-hydroxytryptamine type 1A (5-HT1A) receptor,which selectively binds to the 5-HT1A receptor in the brain. The anti-anxiety effect is exerted by inhibiting the activities of the 5-HT1A system via selectively stimulating the 5-HT1A receptor widely distributed in these sites.

Side effects

The most common adverse reactions to Tandospirone citrate include drowsiness, dizziness, headache, nausea, malaise, rash, urticaria and pruritus. In addition, there are some symptoms that require special attention, such as those related to hepatic insufficiency and jaundice: general malaise, loss of appetite, yellowing of the skin and whites of the eyes. Excitement, sweating and trembling associated with serotonin syndrome. Fever, impaired consciousness, sweating associated with malignant syndrome. These symptoms are rarely considered initial symptoms of the indicated adverse reaction. However, if you experience discomfort, contact your doctor immediately.

87760-53-0
77-92-9
112457-95-1
Synthesis of Tandospirone citrate from Tandospirone and Citric acid

Tandospirone citrate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 168)Suppliers
Supplier Tel Email Country ProdList Advantage
Chengdu Aupone Pharmaceutical Co.Ltd.
+86-28-+86-28-87843998-6060-6060 +86-18980796919 lijiaqi@aupone.com China 55 58
Biopole Pharmatech Co., Ltd.
+86-0086-15151475053 biopole@163.com China 37 58
Wuhan JiyunZen Tech Co., Ltd. 		+86-18062099985 Amyjiyunzen@yeah.net China 672 58
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29812 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19936 58
Fuxin Pharmaceutical 		+86-021-021-50872116 contact@fuxinpharm.com China 9976 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32468 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
Shanxi Xuanran Import and Export Trade Co., Ltd. 		+8617735180244 mike_yan@xuanranglobal.com CHINA 4017 58
Shanghai UCHEM Inc. 		+86-18930848214 +86-021-56762820 sales@myuchem.com China 8886 58

View Lastest Price from Tandospirone citrate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Tandospirone citrate pictures 2026-07-27 Tandospirone citrate
112457-95-1
 $48.00-156.00 99.90% 10g TargetMol Chemicals Inc.
Tandospirone citrate pictures 2026-07-06 Tandospirone citrate
112457-95-1
 $85.00-850.00 10kg 0.99 20tons Zibo Hangyu Biotechnology Development Co., Ltd
Tandospirone citrate pictures 2026-04-10 Tandospirone citrate
112457-95-1
 $2.00-5.00 1KG 99% hplc 500TONS Wuhan JiyunZen Tech Co., Ltd.

Tandospirone citrate Spectrum

4,7-Methano-1H-isoindole-1,3(2H)-dione, hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-, (3aa,4b,7b,7aa)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1) 4,7-Methano-1H-isoindole-1,3(2H)-dione, hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-, (3aR,4S,7R,7aS)-rel-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1) (9CI) SM 3997 tandospirone citrate (3aα,4β,7β,7aα)-Hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dione·citric acid Methanospirone Tandopsirone citrate 3aalpha,4alpha,5,6,7alpha,7aalpha-Hexahydro-2-[4- [4-(2-pyriMidinyl)-1-piperazinyl]butyl]-4,7-Methano-1H-isoindole-1,3(2H)-dione dihydrogen citrate (3aR,4S,7R,7aS)-rel-Hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dione 2-hydroxy-1,2,3-propanetricarboxylate (1:1) SM-3997 citrate rel-(3aR,4S,7R,7aS)-2-(4-(4-(Pyrimidin-2-yl)piperazin-1-yl)butyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione 2-hydroxypropane-1,2,3-tricarboxylate Tandospirone citrate (SM 3997) Tandospirone-d8 Citrate andospironecitrate SM3997,SM-3997,Tandospirone,Tandospirone citrate,Inhibitor,Serotonin Receptor,SM 3997,5-hydroxytryptamine Receptor,inhibit,5-HT Receptor 2-(Dicyclohexylphosphanyl)-1-(2-methoxy-6-(triethylsilyl)phenyl)-1H-pyrrole 4-((3aR,4S,7R,7aS)-1,3-dioxooctahydro-2H-4,7-methanoisoindol-2-yl)butyl 4-(pyrimidin-2-yl)piperazine-1-carboxylate (1S,2R,3S,4R)-3-((4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)carbamoyl)bicyclo[2.2.1]heptane-2-carboxylic acid (3aR,3a'R,4S,4'S,7R,7aS,7'R,7a'S)-2,2'-(piperazine-1,4-diylbis(butane-4,1-diyl))bis(hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione) (3aR,4R,7S,7aS)-2-(4-chlorobutyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione (3aR,4S,7R,7aS)-2-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-dione 2-hydroxypropane-1,2,3-tricarboxylate 112457-95-1 C21H29N5O2C6H8O7 112457-95-1 API
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