Raubasine
- CAS No.
- 483-04-5
- Chemical Name:
- Raubasine
- Synonyms
- AJMALICINE;Tensyl;Sarpan;Vincain;Vincein;Lamuran;Ranitol;RAUBASIN;Vinceine;Vincaine
- CBNumber:
- CB7129678
- Molecular Formula:
- C21H24N2O3
- Molecular Weight:
- 352.43
- MDL Number:
- MFCD00042748
- MOL File:
- 483-04-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Ajmalicine ≥98.0% (HPLC) | 41111 | 50mg | $289 |
| Ajmalicine ≥98.0% (HPLC) | 41111 | 10mg | $77.7 |
| AJMALICINE AldrichCPR | R751618 | 50MG | $97.9 |
| Ajmalicine ≥98% | 31213 | 5mg | $36 |
| Ajmalicine ≥98% | 31213 | 10mg | $63 |
| More product size | |||
| Melting point | 258°C (rough estimate) |
|---|---|
| Boiling point | 486.04°C (rough estimate) |
| alpha | D20 -60° (c = 0.5 in chloroform); D20 -45° (c = 0.5 in pyridine); D20 -39° (c = 0.25 in methanol) |
| Density | 1.1823 (rough estimate) |
| refractive index | 1.6500 (estimate) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly, Heated) |
| form | Solid |
| pka | pK1:10.55(+1) (25°C) |
| color | Pale Yellow |
| optical activity | [α]/D -65±3°, c = 1 in chloroform |
| Water Solubility | insoluble in water |
| BRN | 97268 |
| LogP | 2.880 (est) |
| EWG's Food Scores | 1 |
| FDA UNII | 4QJL8OX71Z |
| NIST Chemistry Reference | Ajmalicine(483-04-5) |
Raubasine price More Price(69)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 41111 | Ajmalicine ≥98.0% (HPLC) | 483-04-5 | 50mg | $289 | 2025-07-31 | Buy |
| Sigma-Aldrich | 41111 | Ajmalicine ≥98.0% (HPLC) | 483-04-5 | 10mg | $77.7 | 2023-06-20 | Buy |
| Sigma-Aldrich | R751618 | AJMALICINE AldrichCPR | 483-04-5 | 50MG | $97.9 | 2022-05-15 | Buy |
| Cayman Chemical | 31213 | Ajmalicine ≥98% | 483-04-5 | 5mg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 31213 | Ajmalicine ≥98% | 483-04-5 | 10mg | $63 | 2026-04-30 | Buy |
Raubasine Chemical Properties,Uses,Production
Description
Vinca rosea L. yields this alkaloid which crystallizes as colourless needles from MeOH. The base is laevorotatory having a specific rotation of [α]D_620 (MeOH) and forms a crystalline hydrochloride, m.p. 281-3°e. The structure given above has been elucidated from chemical and spectroscopic data.
Uses
Antihypertensive, anti-ischemic.
Uses
Antihypertensive, anti-ischemic (cerebral and peripheral)
Definition
ChEBI: Ajmalicine is a monoterpenoid indole alkaloid with formula C21H24N2O3, isolated from several Rauvolfia and Catharanthus species. It is a selective alpha1-adrenoceptor antagonist used for the treatment of high blood pressure. It has a role as an antihypertensive agent, an alpha-adrenergic antagonist and a vasodilator agent. It is a monoterpenoid indole alkaloid, a methyl ester and an organic heteropentacyclic compound. It is a conjugate base of an ajmalicine(1+).
target
P450 (e.g. CYP17)
Purification Methods
It crystallises from MeOH, EtOH or EtOAc. [Beilstein 27 III/IV 7927.]
References
Janot, Le Men, Cornpt. Rend., 243, 1786 (1956) Shamma, Moss, J. Arner. Chern. Soc., 83, 5038 (1961) Abdurakhsimova, Yuldashev, Yunusov, Khirn. Prir. Soedin., 1,224 (1965)
Raubasine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21585 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 4616 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from Raubasine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-14 | Ajmalicine
483-04-5
|
$40.00-64.00 | 99.89% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-03-20 | Raubasine
483-04-5
|
$10.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2024-04-23 | Raubasine
483-04-5
|
$50.00 | 1kg | 99.10% | 50000kg | Ouhuang Engineering Materials (Hubei) Co., Ltd |
-
- Ajmalicine
483-04-5
- $40.00-64.00
- 99.89%
- TargetMol Chemicals Inc.
-
- Raubasine
483-04-5
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Raubasine
483-04-5
- $50.00
- 99.10%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
