ChemicalBook >> CAS DataBase List >>1-BOC-4-(4-FORMYLPHENYL)PIPERAZINE
1-BOC-4-(4-FORMYLPHENYL)PIPERAZINE
- CAS No.
- 197638-83-8
- Chemical Name:
- 1-BOC-4-(4-FORMYLPHENYL)PIPERAZINE
- Synonyms
- BUTTPARK 98\06-98;1-BOC-4-(4-FORMYLPHENYL)PIPERAZINE;4-(N-BOC-PIPERAZIN-1-YL)BENZALDEHYDE;1-boc-4-(4-formylphenyl)piperazine,97%;4-Piperazin-1-ylbenzaldehyde, N4-BOC protected;4-(4-TERT-BUTOXYCARBONYL)PIPERAZINEBENZALDEHYDE;TERT-BUTYL 4-(4'-FORMYLPHENYL)PIPERAZINE-1-CARBOXYLATE;1-BOC-4-(4-FORMYLPHENYL)PIPERAZINE ISO 9001：2015 REACH;1,1-Dimethylethyl 4-(4-formylphenyl)-1-piperazinecarboxylate;4-(4-FORMYLPHENYL)PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
- CBNumber:
- CB7157734
- Molecular Formula:
- C16H22N2O3
- Molecular Weight:
- 290.36
- MDL Number:
- MFCD05864663
- MOL File:
- 197638-83-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-06-04 16:00:12
| Product description | Number | Pack Size | Price |
| 1-Boc-4-(4-formylphenyl)piperazine 97% | 651427 | 1g | $73.1 |
| 1-Boc-4-(4-formylphenyl)piperazine 97% | 651427 | 5g | $240 |
| 4-Piperazin-1-ylbenzaldehyde, N4-BOC protected >95% | OR14490 | 250mg | $21 |
| 4-Piperazin-1-ylbenzaldehyde, N4-BOC protected >95% | OR14490 | 1g | $24 |
| 4-Piperazin-1-ylbenzaldehyde, N4-BOC protected >95% | OR14490 | 5g | $29 |
| Melting point | 118-121 °C (lit.) |
|---|---|
| Boiling point | 441.4±40.0 °C(Predicted) |
| Density | 1.154±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | solid |
| pka | 2.45±0.10(Predicted) |
| Appearance | Light yellow to yellow Solid |
| Sensitive | Air Sensitive |
| InChI | InChI=1S/C16H22N2O3/c1-16(2,3)21-15(20)18-10-8-17(9-11-18)14-6-4-13(12-19)5-7-14/h4-7,12H,8-11H2,1-3H3 |
| InChIKey | KHORERZDMJTBMR-UHFFFAOYSA-N |
| SMILES | N1(C(OC(C)(C)C)=O)CCN(C2=CC=C(C=O)C=C2)CC1 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H317 | |||||||||
| Precautionary statements | P261-P280g-P301+P310a-P321-P405-P501a-P280-P301+P310 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 25-43 | |||||||||
| Safety Statements | 36/37-45 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 6.1 | |||||||||
| HS Code | 2933599590 | |||||||||
| Storage Class | 6.1D - Non-combustible acute toxic Cat.3 toxic hazardous materials or hazardous materials causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 3 Oral Skin Sens. 1 |
|||||||||
| Limited Quantities | 5.0 kg (11 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
1-BOC-4-(4-FORMYLPHENYL)PIPERAZINE price More Price(63)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 651427 | 1-Boc-4-(4-formylphenyl)piperazine 97% | 197638-83-8 | 1g | $73.1 | 2023-06-20 | Buy |
| Sigma-Aldrich | 651427 | 1-Boc-4-(4-formylphenyl)piperazine 97% | 197638-83-8 | 5g | $240 | 2023-06-20 | Buy |
| Apolloscientific | OR14490 | 4-Piperazin-1-ylbenzaldehyde, N4-BOC protected >95% | 197638-83-8 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR14490 | 4-Piperazin-1-ylbenzaldehyde, N4-BOC protected >95% | 197638-83-8 | 1g | $24 | 2026-06-04 | Buy |
| Apolloscientific | OR14490 | 4-Piperazin-1-ylbenzaldehyde, N4-BOC protected >95% | 197638-83-8 | 5g | $29 | 2026-06-04 | Buy |
1-BOC-4-(4-FORMYLPHENYL)PIPERAZINE Chemical Properties,Uses,Production
Synthesis
459-57-4
57260-71-6
197638-83-8
Step 1: Anhydrous potassium carbonate (8.5 g, 62 mmol) was added to a solution of N-methyl-2-pyrrolidinone (NMP, 30 mL) containing p-fluorobenzaldehyde (3.9 g, 31 mmol) and N-BOC-piperazine (6.3 g, 34 mmol) under nitrogen protection. The reaction mixture was stirred at 135 °C for 12 hours. The progress of the reaction was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the mixture was slowly poured into ice water (100 mL) and a yellow solid was precipitated. The precipitate was collected by filtration and washed three times (20 mL each) with cold water and dried under vacuum to give 1-BOC-4-(4-formylphenyl)piperazine as a yellow solid (6.4 g, 72% yield).
References
[1] Patent: WO2016/57779, 2016, A2. Location in patent: Page/Page column 68
[2] Journal of Medicinal Chemistry, 2016, vol. 59, # 6, p. 2747 - 2759
[3] Chemical Communications, 2016, vol. 52, # 67, p. 10289 - 10292
[4] Patent: WO2008/154642, 2008, A2. Location in patent: Page/Page column 155-156
[5] Patent: US2003/13737, 2003, A1
1-BOC-4-(4-FORMYLPHENYL)PIPERAZINE Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1-BOC-4-(4-FORMYLPHENYL)PIPERAZINE Suppliers
Global( 108)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49979 | 58 | |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29792 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1059@dideu.com | China | 29093 | 58 |
| Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 20000 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +86-18949823763 | sales@tnjchem.com | China | 25356 | 58 |
| Nanjing Bicbiotechnology Co., Ltd | +86-2552131256 +86-18251840740 | sales@bicbiotech.com | China | 5994 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53803 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
View Lastest Price from 1-BOC-4-(4-FORMYLPHENYL)PIPERAZINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-18 | 1-BOC-4-(4-FORMYLPHENYL)PIPERAZINE
197638-83-8
|
$1.10 | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2020-01-03 | 1-BOC-4-(4-FORMYLPHENYL)PIPERAZINE
197638-83-8
|
$1.00 | 1KG | 95-99% | 1ton | Career Henan Chemical Co |
-
- 1-BOC-4-(4-FORMYLPHENYL)PIPERAZINE
197638-83-8
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 1-BOC-4-(4-FORMYLPHENYL)PIPERAZINE
197638-83-8
- $1.00
- 95-99%
- Career Henan Chemical Co
197638-83-8(1-BOC-4-(4-FORMYLPHENYL)PIPERAZINE)Related Search:
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1-BOC-4-(4-FORMYLPHENYL)PIPERAZINE
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1-BOC-4-(4-FORMYLPHENYL)PIPERAZINE ISO 9001：2015 REACH
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197638-83-8
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