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ChemicalBook >> CAS DataBase List >>Crystal violet lactone

Crystal violet lactone

CAS No.
1552-42-7
Chemical Name:
Crystal violet lactone
Synonyms
CVL;Copikem I;violet lactone;6-(Dimethylamino)-3,3-bis[4-(dimethylamino)phenyl]phthalide;CVIL;HEL70;IMD50;HEL-S-105;Pergascript Blue I 2R;CRYSTAL VIOLET LACTONE
CBNumber:
CB7218930
Molecular Formula:
C26H29N3O2
Molecular Weight:
415.53
MDL Number:
MFCD00070611
MOL File:
1552-42-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:47:34
Product description Number Pack Size Price
Crystal Violet lactone Dye content 97% 332488 5g $87.4
Crystal Violet lactone Dye content 97% 332488 25g $139
Crystal Violet Lactone >97.0%(HPLC)(T) C0741 25g $102
Crystal Violet Lactone 267370 50g $382
Crystal Violet Lactone 267370 100g $505
More product size

Crystal violet lactone Properties

Melting point 180-183°C
Boiling point 534.12°C (rough estimate)
Density 1.1424 (rough estimate)
vapor pressure 0Pa at 25℃
refractive index 1.7120 (estimate)
storage temp. Sealed in dry,Room Temperature
form Powder
pka 4.73±0.24(Predicted)
color White to Light yellow
Water Solubility <0.1 g/100 mL at 22.5 ºC
λmax 354 nm
Major Application diagnostic assay manufacturing
hematology
histology
InChI InChI=1S/C26H29N3O2/c1-27(2)20-11-7-18(8-12-20)26(19-9-13-21(14-10-19)28(3)4)24-16-15-22(29(5)6)17-23(24)25(30)31-26/h7-17H,1-6H3
InChIKey IPAJDLMMTVZVPP-UHFFFAOYSA-N
SMILES C1(=O)C2=C(C=CC(N(C)C)=C2)C(C2=CC=C(N(C)C)C=C2)(C2=CC=C(N(C)C)C=C2)O1
LogP 4.95 at 25℃
CAS DataBase Reference 1552-42-7(CAS DataBase Reference)
FDA UNII USS7CW0676
EPA Substance Registry System Crystal violet lactone (1552-42-7)
UNSPSC Code 12171500
NACRES NA.47

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39
WGK Germany  3
TSCA  TSCA listed
HS Code  29322090
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
REACH Registrations Active
NFPA 704
1
1 0

Crystal violet lactone price More Price(62)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 332488 Crystal Violet lactone Dye content 97% 1552-42-7 5g $87.4 2026-04-30 Buy
Sigma-Aldrich 332488 Crystal Violet lactone Dye content 97% 1552-42-7 25g $139 2026-04-30 Buy
TCI Chemical C0741 Crystal Violet Lactone >97.0%(HPLC)(T) 1552-42-7 25g $102 2026-04-30 Buy
Usbiological 267370 Crystal Violet Lactone 1552-42-7 50g $382 2026-06-03 Buy
Usbiological 267370 Crystal Violet Lactone 1552-42-7 100g $505 2026-06-03 Buy
Product number Packaging Price Buy
332488 5g $87.4 Buy
332488 25g $139 Buy
C0741 25g $102 Buy
267370 50g $382 Buy
267370 100g $505 Buy

Crystal violet lactone Chemical Properties,Uses,Production

Chemical Properties

Light yellow solid

Uses

Crystal Violet lactone is an important functional dye for the production of pressure sensitive materials. It is a chemical intermediate , intermediates for thermal/carbonless Paper, used in medicine and biochemical research, a leuco dye..

Definition

ChEBI: Crystal violet lactone is a member of benzofurans.

General Description

Blue-green crystals or pale green powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Crystal violet lactone may be sensitive to excessive light and heat.

Health Hazard

SYMPTOMS: Symptoms of exposure to Crystal violet lactone may include irritation.

Fire Hazard

Flash point data for Crystal violet lactone are not available; however, Crystal violet lactone is probably combustible.

Flammability and Explosibility

Non flammable

Synthesis

2-[bis[4-(dimethylamino)phenyl]methyl]-5-(dimethylamino)benzoic acid

1255-69-2

Crystal violet lactone

1552-42-7

Example 1: 21.5 g (97.0% purity) of 2-[4,4'-bis(dimethylamino)diphenylmethyl]-5-dimethylaminobenzoic acid was added to a 500 mL three-necked flask, followed by 250 mL of deionized water. The resulting suspension was stirred with the addition of 21.5 g of activated carbon (Model: SHIRASAGI-C, manufactured by Takeda Chemical Industries) and 2.0 g of 49% NaOH aqueous solution. The reaction system was heated to 90-95°C and maintained in this temperature range. During the reaction, air was passed into the reaction system at a rate of 400 mL/min for 9 hours. Upon completion of the reaction, the reaction mixture was filtered while hot, the filter cake was collected and re-slurried with deionized water. 19.5 g of 36% HCl aqueous solution was slowly added to the slurried solution until the solid was completely dissolved. Subsequently, the activated carbon was removed by filtration. The pH of the filtrate was adjusted to 7.0 with 49% NaOH aqueous solution and crystals of the target product were precipitated. The crystals were collected by filtration, washed with cold water and dried under vacuum to give 20.1 g of 3,3-bis(4-dimethylaminophenyl)-6-dimethylaminophthalide in 95.4% yield. Analyzed by HPLC, the by-product generation rate was 1.5% and the reaction selectivity was 98.4%.

References

[1] Patent: US5973168, 1999, A
[2] Journal of Organic Chemistry USSR (English Translation), 1986, vol. 22, # 10, p. 2012 - 2014
[3] Zhurnal Organicheskoi Khimii, 1986, vol. 22, # 10, p. 2240 - 2241
[4] Patent: US4595768, 1986, A
[5] Patent: US4271075, 1981, A

1255-69-2
1552-42-7
Synthesis of Crystal violet lactone from 2-[bis[4-(dimethylamino)phenyl]methyl]-5-(dimethylamino)benzoic acid
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View Lastest Price from Crystal violet lactone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Crystal violet lactone pictures 2026-07-30 Crystal violet lactone
1552-42-7
0.99 RongNa Biotechnology Co.,Ltd
Crystal violet lactone pictures 2026-07-24 Crystal violet lactone
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1KG 99% 200mt/year Jinan Finer Chemical Co., Ltd
violet lactone pictures 2026-05-28 violet lactone
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$9.00 1ASSAYS 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
3,3-bis(p-Dimethylaminophenyl)-6-dimethylaminophthalate 6-(dimethylamino)-3,3-bis[4-(dimethylamino)phenyl]-1(3h)-isobenzofuranon Pergascript Blue I 2R 6-(dimethylamino)-3,3-bis(4-(dimethylamino)phenyl)-1(3h)-isobenzofuranone 6-(DIMETHYLAMINO)-3,3-BIS[P-(DIMETHYLAMINO)PHENYL]PHTHALIDE 3,3-BIS(P-DIMETHYLAMINOPHENYL)-6-DIMETHYLAMINOPHTHALIDE 3,3-BIS-4-DIMETHYLAMINOPHENYL-6-DIMETHYLAMINOPHTHALIDE CRYSTAL VIOLET LACTONE 1(3H)-Isobenzofuranone, 6-(dimethylamino)-3,3-bis4-(dimethylamino)phenyl- 6-Dimethylamino-3,3-bis(4-dimethylaminophenyl)-2-benzofuran-1-one 6-(Dimethylamino)-3,3-bis[4-(dimethylamino)phenyl]isobenzofuran-1(3H)-one 6-Dimethylamino-3,3-bis(p-dimethylaminophenyl)isobenzofuran-1(3H)-one LABOTEST-BB LT00160000 4-dimethylaminophenyl-6-dimethylaminophthalide 3,3-Bis-4-Dimethylaminophenyl7-6-Dimethylaminophthalide CVL 3,3-BIS-4-DIMETHYLAMINOPHENYL7-6-DIMETHYLAMINOPHTHALIDE 6-(dimethylamino)-3,3-bis[4-(dimethylamino)phenyl]isobenzofuran-1-one Crystal Violet Lactone (CVL) 3,3-Bis(p-dimethylaminophenyl)-6-dimethylaminophthalide 6-(Dimethylamino)-3,3-bis[p-(dimethylamino)phenyl]phthalide High Purity Cvl, Crystal Violet Lactone, CAS No. 1552-42-7 for Press-Sensitive Paper Crystal violet lactone, dye content, 97% Crystal Violet Lactone > violet lactone Crystal Violet Lactone, ≥ 95.0% CVIL HEL70 HEL-S-105 IMD50 6-(Dimethylamino)-3,3-bis[4-(dimethylamino)phenyl]phthalide Copikem I CVL 1552-42-7 1522-42-7 C26H29N3O2 Color Former Color Former & Related Compounds Pharmaceutical intermediates Organics Color Former Color Former & Related Compounds Functional Materials C Stains and Dyes Stains&Dyes, A to john's
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