ChemicalBook >> CAS DataBase List >>"5-(2-amino-4-oxo-3-(2-(trifluoromethyl)phenyl)-3,4-dihydroquinazolin-6-yl)-N-(2,4-difluorophenyl)-2-methoxypyridine-3-sulfonamide "
"5-(2-amino-4-oxo-3-(2-(trifluoromethyl)phenyl)-3,4-dihydroquinazolin-6-yl)-N-(2,4-difluorophenyl)-2-methoxypyridine-3-sulfonamide "
- CAS No.
- 1384097-27-1
- Chemical Name:
- "5-(2-amino-4-oxo-3-(2-(trifluoromethyl)phenyl)-3,4-dihydroquinazolin-6-yl)-N-(2,4-difluorophenyl)-2-methoxypyridine-3-sulfonamide "
- Synonyms
- (3S)-GSK-F1;(3S)-GSK-F1, 10 mM in DMSO;5-(2-AMINO-4-OXO-3-(2-(TRIFLUOROMETHYL)PHENYL)-3,4-DIHYDROQUIZOLIN-6-YL)-N-(2,4-DIFLUOROPHENYL)-2-METHOXYPYRIDINE-3-SULFOMIDE;"5-(2-amino-4-oxo-3-(2-(trifluoromethyl)phenyl)-3,4-dihydroquinazolin-6-yl)-N-(2,4-difluorophenyl)-2-methoxypyridine-3-sulfonamide ";3-Pyridinesulfonamide, 5-[(3S)-2-amino-3,4-dihydro-4-oxo-3-[2-(trifluoromethyl)phenyl]-6-quinazolinyl]-N-(2,4-difluorophenyl)-2-methoxy-
- CBNumber:
- CB73120812
- Molecular Formula:
- C27H18F5N5O4S
- Molecular Weight:
- 603.52
- MDL Number:
- MFCD29770785
- MOL File:
- 1384097-27-1.mol
- MSDS File:
- SDS
Last updated:2026-07-14 16:49:18
| Product description | Number | Pack Size | Price |
| (S)-GSK-F1 98.01% | CS-1097310 | 1mg | $138 |
| (S)-GSK-F1 98.01% | CS-1097310 | 5mg | $318 |
| (S)-GSK-F1 98.01% | CS-1097310 | 10mg | $480 |
| (S)-GSK-F1 98.01% | CS-1097310 | 25mg | $822 |
| (S)-GSK-F1 98.01% | CS-1097310 | 50mg | $1127 |
| More product size | |||
"5-(2-amino-4-oxo-3-(2-(trifluoromethyl)phenyl)-3,4-dihydroquinazolin-6-yl)-N-(2,4-difluorophenyl)-2-methoxypyridine-3-sulfonamide " price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-1097310 | (S)-GSK-F1 98.01% | 1384097-27-1 | 1mg | $138 | 2026-06-04 | Buy |
| ChemScene | CS-1097310 | (S)-GSK-F1 98.01% | 1384097-27-1 | 5mg | $318 | 2026-06-04 | Buy |
| ChemScene | CS-1097310 | (S)-GSK-F1 98.01% | 1384097-27-1 | 10mg | $480 | 2026-06-04 | Buy |
| ChemScene | CS-1097310 | (S)-GSK-F1 98.01% | 1384097-27-1 | 25mg | $822 | 2026-06-04 | Buy |
| ChemScene | CS-1097310 | (S)-GSK-F1 98.01% | 1384097-27-1 | 50mg | $1127 | 2026-06-04 | Buy |
"5-(2-amino-4-oxo-3-(2-(trifluoromethyl)phenyl)-3,4-dihydroquinazolin-6-yl)-N-(2,4-difluorophenyl)-2-methoxypyridine-3-sulfonamide " Chemical Properties,Uses,Production
Uses
(S)-GSK-F1 (Compound 28) is an inhibitor for type III phosphatidylinositol 4-kinase α (PI4KIIIα). (S)-GSK-F1 inhibits PI4Kα, PI4Kβ, PI4Kγ, PI3Kα, PI3Kβ and PI3Kδ with pIC50 of 8.3, 6.0, 5.6, 5.6, 5.1 and 5.6, respectively. (S)-GSK-F1 exhibits anti-hepatitis C virus (HCV) activity through inhibition of HCV replication. (S)-GSK-F1 exhibits moderate pharmacokinetic characters in rat model[1].
IC 50
PI4KIIIα: 8.3 (pIC50); PI4KIIIβ: 6.0 (pIC50); PI3Kα: 5.6 (pIC50); PI3Kδ: 5.6 (pIC50); PI3Kβ: 5.1 (pIC50)
References
[1] Leivers AL, et al., Discovery of selective small molecule type III phosphatidylinositol 4-kinase alpha (PI4KIIIα) inhibitors as anti hepatitis C (HCV) agents. J Med Chem. 2014 Mar 13;57(5):2091-106. DOI:10.1021/jm400781h
"5-(2-amino-4-oxo-3-(2-(trifluoromethyl)phenyl)-3,4-dihydroquinazolin-6-yl)-N-(2,4-difluorophenyl)-2-methoxypyridine-3-sulfonamide " Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 30)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| Xi'an MC Biotech, Co., Ltd. | 029-89275612 +8618991951683 | mcbio_sales@163.com | China | 2251 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | orders@jknbiochem.com | China | 5221 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| AN PharmaTech Co Ltd | 86(21)68097365 | sales@anpharma.net | China | 4891 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9804 | 58 |
View Lastest Price from "5-(2-amino-4-oxo-3-(2-(trifluoromethyl)phenyl)-3,4-dihydroquinazolin-6-yl)-N-(2,4-difluorophenyl)-2-methoxypyridine-3-sulfonamide " manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-14 | (3S)-GSK-F1
1384097-27-1
|
$67.00-233.00 | 99.35% | 10g | TargetMol Chemicals Inc. | ||
 |
2020-02-02 | 5-(2-AMINO-4-OXO-3-(2-(TRIFLUOROMETHYL)PHENYL)-3,4-DIHYDROQUINAZOLIN-6-YL)-N-(2,4-DIFLUOROPHENYL)-2-METHOXYPYRIDINE-3-SULFONAMIDE
1384097-27-1
|
$1.00 | 1KG | 99%HPLC | 200KG | Career Henan Chemical Co |
-
- (3S)-GSK-F1
1384097-27-1
- $67.00-233.00
- 99.35%
- TargetMol Chemicals Inc.
-
- 5-(2-AMINO-4-OXO-3-(2-(TRIFLUOROMETHYL)PHENYL)-3,4-DIHYDROQUINAZOLIN-6-YL)-N-(2,4-DIFLUOROPHENYL)-2-METHOXYPYRIDINE-3-SULFONAMIDE
1384097-27-1
- $1.00
- 99%HPLC
- Career Henan Chemical Co
"5-(2-amino-4-oxo-3-(2-(trifluoromethyl)phenyl)-3,4-dihydroquinazolin-6-yl)-N-(2,4-difluorophenyl)-2-methoxypyridine-3-sulfonamide " Spectrum
"5-(2-amino-4-oxo-3-(2-(trifluoromethyl)phenyl)-3,4-dihydroquinazolin-6-yl)-N-(2,4-difluorophenyl)-2-methoxypyridine-3-sulfonamide "
3-Pyridinesulfonamide, 5-[(3S)-2-amino-3,4-dihydro-4-oxo-3-[2-(trifluoromethyl)phenyl]-6-quinazolinyl]-N-(2,4-difluorophenyl)-2-methoxy-
5-(2-AMINO-4-OXO-3-(2-(TRIFLUOROMETHYL)PHENYL)-3,4-DIHYDROQUIZOLIN-6-YL)-N-(2,4-DIFLUOROPHENYL)-2-METHOXYPYRIDINE-3-SULFOMIDE
(3S)-GSK-F1
(3S)-GSK-F1, 10 mM in DMSO
1384097-27-1
