4-Bromo-2-nitrobenzaldehyde
- CAS No.
- 5551-12-2
- Chemical Name:
- 4-Bromo-2-nitrobenzaldehyde
- Synonyms
- Nifedipine Impurity 20;4-BROMO-2-NITROBENZALDEHYDE;Benzaldehyde, 4-bromo-2-nitro-;4-BroMo-2-nitrobenzaldehyde, 95+%;4'-Amino-3',6'-difluoroacetophenone;4-Bromo-2-nitrobenzaldehyde, 97%min;2-Nitro-4-brom-benzaldehyd,2-nitro-4-bromobenzaldehyde,4-bromo-2-nitro-benzaldehyde,4-Brom-2-nitro-benzaldehyd
- CBNumber:
- CB8137003
- Molecular Formula:
- C7H4BrNO3
- Molecular Weight:
- 230.02
- MDL Number:
- MFCD00463687
- MOL File:
- 5551-12-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-Bromo-2-nitrobenzaldehyde 97% | 756628 | 1g | $74.8 |
| 4-Bromo-2-nitrobenzaldehyde >96.0%(GC) | B4146 | 1g | $37 |
| 4-Bromo-2-nitrobenzaldehyde >96.0%(GC) | B4146 | 5g | $143 |
| 4-Bromo-2-nitrobenzaldehyde | FB63999 | 0.05kg | $317.07 |
| 4-Bromo-2-nitrobenzaldehyde | FB63999 | 0.1kg | $614.92 |
| More product size | |||
| Melting point | 95.0 to 99.0 °C |
|---|---|
| Boiling point | 334.4±32.0 °C(Predicted) |
| Density | 1.781±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C, stored under nitrogen |
| solubility | soluble in Methanol |
| form | powder to crystal |
| color | Light orange to Yellow to Green |
| λmax | 260nm(CH3CN)(lit.) |
| InChI | InChI=1S/C7H4BrNO3/c8-6-2-1-5(4-10)7(3-6)9(11)12/h1-4H |
| InChIKey | GSXUXSXBEUJRAJ-UHFFFAOYSA-N |
| SMILES | C(=O)C1=CC=C(Br)C=C1[N+]([O-])=O |
| CAS DataBase Reference | 5551-12-2(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H317-H319-H335-H400 | |||||||||
| Precautionary statements | P273-P280-P301+P312+P330-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| Hazard Codes | Xn,N | |||||||||
| Risk Statements | 22-36/37/38-43-50 | |||||||||
| Safety Statements | 26-36/37-61 | |||||||||
| RIDADR | UN 3077 9 / PGIII | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2913000090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Acute 1 Eye Irrit. 2 Skin Irrit. 2 Skin Sens. 1 STOT SE 3 |
|||||||||
| NFPA 704 |
|
4-Bromo-2-nitrobenzaldehyde price More Price(79)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 756628 | 4-Bromo-2-nitrobenzaldehyde 97% | 5551-12-2 | 1g | $74.8 | 2023-06-20 | Buy |
| TCI Chemical | B4146 | 4-Bromo-2-nitrobenzaldehyde >96.0%(GC) | 5551-12-2 | 1g | $37 | 2026-04-30 | Buy |
| TCI Chemical | B4146 | 4-Bromo-2-nitrobenzaldehyde >96.0%(GC) | 5551-12-2 | 5g | $143 | 2026-04-30 | Buy |
| Biosynth | FB63999 | 4-Bromo-2-nitrobenzaldehyde | 5551-12-2 | 0.05kg | $317.07 | 2026-06-04 | Buy |
| Biosynth | FB63999 | 4-Bromo-2-nitrobenzaldehyde | 5551-12-2 | 0.1kg | $614.92 | 2026-06-04 | Buy |
4-Bromo-2-nitrobenzaldehyde Chemical Properties,Uses,Production
Uses
4-Bromo-2-nitrobenzaldehyde is used along with in the synthesis of Tyrian Purple as a teaching material, from o-Nitrotoluene via 4-Bromo-2-nitrotoluene and 4-Bromo-2-nitrobenzylidene diacetate;Also, it is used as a starting material in the synthesis of heterocyclyl as HDAC3 inhibitors.
Synthesis Reference(s)
The Journal of Organic Chemistry, 72, p. 5867, 2007 DOI: 10.1021/jo070477u
Synthesis
60956-26-5
5551-12-2
Step A: Concentrated sulfuric acid (324 mL) was added slowly and dropwise to a solution of 4-bromo-1-methyl-2-nitrobenzene (300 g, 1.38 mol) in acetic anhydride (2400 mL) at 0 °C. Subsequently, a solution of chromium trioxide (384 g, 3.84 mol) dissolved in acetic anhydride (2160 mL) was added, keeping the internal temperature of the reaction system below 10 °C during the process. The reaction mixture was stirred for 1 hour and then slowly poured into an ice-water mixture. The solid product was collected by filtration and washed with plenty of water until the washings were colorless. The resulting solid was suspended in 1800 mL of a 2% aqueous sodium carbonate solution, stirred thoroughly and then filtered again, washed with water and finally dried under reduced pressure. [000195] The diacetate product obtained above was suspended in a mixed solution comprising 1360 mL of concentrated hydrochloric acid, 1250 mL of water and 480 mL of ethanol and refluxed for 45 minutes. After the reaction was completed, it was cooled to room temperature, the solid product was collected by filtration and washed with water. The final 4-bromo-2-nitrobenzaldehyde (147 g, 45% overall yield in two steps) was obtained as a brown solid, which could be used in the subsequent reaction without further purification.
References
[1] Patent: WO2012/97177, 2012, A2. Location in patent: Page/Page column 57-58
[2] Bioorganic and Medicinal Chemistry, 2006, vol. 14, # 7, p. 2462 - 2467
[3] Organic Preparations and Procedures International, 2006, vol. 38, # 3, p. 325 - 331
[4] Synthetic Communications, 2001, vol. 31, # 23, p. 3721 - 3727
[5] Heterocycles, 1994, vol. 39, # 2, p. 767 - 778
4-Bromo-2-nitrobenzaldehyde Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Win-Win Chemical CO., Limited | 0086-577-64498589 | sales@win-winchemical.com | CHINA | 998 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 +86-17392581500 | 1015@dideu.com | China | 3861 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 9976 | 58 |
View Lastest Price from 4-Bromo-2-nitrobenzaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-20 | 4-Bromo-2-nitrobenzaldehyde
5551-12-2
|
$10.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2024-04-24 | 4-Bromo-2-nitrobenzaldehyde
5551-12-2
|
$30.00-100.00 | 1kg | 99.93% | 1000kg per week | Ouhuang Engineering Materials (Hubei) Co., Ltd | |
 |
2020-01-10 | 4-Bromo-2-nitrobenzaldehyde
5551-12-2
|
$6.68 | 1KG | 97%-99% | 1kg-1000kg | Career Henan Chemical Co |
-
- 4-Bromo-2-nitrobenzaldehyde
5551-12-2
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 4-Bromo-2-nitrobenzaldehyde
5551-12-2
- $30.00-100.00
- 99.93%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
-
- 4-Bromo-2-nitrobenzaldehyde
5551-12-2
- $6.68
- 97%-99%
- Career Henan Chemical Co
5551-12-2(4-Bromo-2-nitrobenzaldehyde)Related Search:
1of4
