MAHANINE
- CAS No.
- 28360-49-8
- Chemical Name:
- MAHANINE
- Synonyms
- MAHANINE;(-)-Mahanin;(R)-Mahanine;(3R)-3,11-Dihydro-3,5-dimethyl-3-(4-methyl-3-penten-1-yl)pyrano[3,2-a]carbazol-9-ol;Pyrano[3,2-a]carbazol-9-ol, 3,11-dihydro-3,5-dimethyl-3-(4-methyl-3-penten-1-yl)-, (3R)-
- CBNumber:
- CB81421484
- Molecular Formula:
- C23H25NO2
- Molecular Weight:
- 347.45
- MDL Number:
- MFCD28137735
- MOL File:
- 28360-49-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Mahanine ≥98% | 380765 | 5mg | $745 |
| (R)-Mahanine | DBA36049 | 0.5mg | $389.4 |
| (R)-Mahanine | DBA36049 | 1mg | $649 |
| (R)-Mahanine | DBA36049 | 2mg | $1038.4 |
| (R)-Mahanine | DBA36049 | 5mg | $1557.6 |
MAHANINE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 380765 | Mahanine ≥98% | 28360-49-8 | 5mg | $745 | 2026-06-03 | Buy |
| Biosynth | DBA36049 | (R)-Mahanine | 28360-49-8 | 0.5mg | $389.4 | 2026-06-04 | Buy |
| Biosynth | DBA36049 | (R)-Mahanine | 28360-49-8 | 1mg | $649 | 2026-06-04 | Buy |
| Biosynth | DBA36049 | (R)-Mahanine | 28360-49-8 | 2mg | $1038.4 | 2026-06-04 | Buy |
| Biosynth | DBA36049 | (R)-Mahanine | 28360-49-8 | 5mg | $1557.6 | 2026-06-04 | Buy |
MAHANINE Chemical Properties,Uses,Production
Description
This terpene alkaloid, also occurring in the leaves of Murraya koenigii Spreng., is laevorotatory, having [α]D - 24.4°. Two methyl groups, one phenolic hydroxyl, an imino group and an unsaturated side chain are present.
Uses
Mahanine is a carbazole alkaloid with various biological properties. Mahanine is a potent anticancer agent against different types of cancer cells. Mahanine exhibits antileishmanial activity and can be used for Leishmania infection research research.
in vivo
Mahanine (oral gavage; 20 mg/kg/40 mg/kg; b.w/day; 5 days) results in 89.1±4.1% reductions in parasite burden at 20 mg/kg, and leads to 96.2±0.3% reductions in parasite burden at 40 mg/kg in a well-established acute model to control Leishmaniainfection[1].
| Animal Model: | Balb/c mice with virulent AG83 promastigotes[1] |
| Dosage: | 20mg/kg-40 mg/kg |
| Administration: | oral gavage; 20mg/kg/40 mg/kg; b.w/day; 5 days |
| Result: | Had the potential to clear parasite burdenin vivo.Exhibited almost complete reduction of parasite burden, upregulation of NO/iNOS/ROS/IL-12 and Tcell proliferation in vivo. |
IC 50
Leishmania
References
Narasimhan, Paradkar, Kelkar.,lnd. J. Chem., 8,473 (1970)
MAHANINE Preparation Products And Raw materials
Raw materials
Preparation Products
MAHANINE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19936 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39037 | 58 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7750 | 56 |
| Wuhan ChemFaces Biochemical Co., Ltd. | 18607101326 15172504745 | aileen@chemfaces.com | China | 6905 | 55 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8447 | 60 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 13636370518 | shyysw007@163.com | China | 89686 | 60 |
| Shanghai Jizhi Biochemical Technology Co. Ltd. | 021-4009004166/18616739031 18616739031 | 3007523370@qq.com | China | 52678 | 58 |
| Zhejiang Lianshuo Biotechnology Co., Ltd. | 18616526224 | lianshuo@vip.126.com | China | 9607 | 58 |
| BioBioPha Co., Ltd. | 0871-65217109 | y.liu@mail.biobiopha.com | China | 2793 | 58 |
