Methyl 2-amino-4,5-dimethoxybenzoate
- CAS No.
- 26759-46-6
- Chemical Name:
- Methyl 2-amino-4,5-dimethoxybenzoate
- Synonyms
- METHYL 6-AMINOVERATRATE;Methyl 2-aMino-4;TIMTEC-BB SBB008554;5-diMethoxy benzoate;LABOTEST-BB LT00454153;Gefitinib interMediate I;METHYL 4,5-DIMETHOXYANTHRANILATE;6-AMINOVERATRIC ACID METHYL ESTER;Methyl4,5-Dimethoxyanthranilate>2-amino-4,5-dimethoxy-benzate ester
- CBNumber:
- CB8153869
- Molecular Formula:
- C10H13NO4
- Molecular Weight:
- 211.21
- MDL Number:
- MFCD00014904
- MOL File:
- 26759-46-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Methyl 2-amino-4,5-dimethoxybenzoate ≥98.0% (HPLC/NT) | 07725 | 25g | $61.3 |
| Methyl 4,5-Dimethoxyanthranilate >98.0%(GC)(T) | D2749 | 25g | $48 |
| Methyl 2-amino-4,5-dimethoxybenzoate Asreported | 283285 | 5g | $319 |
| Methyl 2-amino-4,5-dimethoxybenzoate Asreported | 283285 | 10g | $418 |
| Methyl 2-amino-4,5-dimethoxybenzoate Asreported | 283285 | 25g | $531 |
| More product size | |||
| Melting point | 128-133 °C |
|---|---|
| Boiling point | 343.1±37.0 °C(Predicted) |
| Density | 1.189±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| form | powder to crystal |
| pka | 2.68±0.10(Predicted) |
| color | White to Light yellow to Light orange |
| BRN | 2724754 |
| Major Application | peptide synthesis |
| InChI | InChI=1S/C10H13NO4/c1-13-8-4-6(10(12)15-3)7(11)5-9(8)14-2/h4-5H,11H2,1-3H3 |
| InChIKey | QQFHCCQSCQBKBG-UHFFFAOYSA-N |
| SMILES | C(OC)(=O)C1=CC(OC)=C(OC)C=C1N |
| CAS DataBase Reference | 26759-46-6(CAS DataBase Reference) |
| UNSPSC Code | 12352200 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338-P280a-P304+P340-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-24/25-22 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29225090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
Methyl 2-amino-4,5-dimethoxybenzoate price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 07725 | Methyl 2-amino-4,5-dimethoxybenzoate ≥98.0% (HPLC/NT) | 26759-46-6 | 25g | $61.3 | 2023-06-20 | Buy |
| TCI Chemical | D2749 | Methyl 4,5-Dimethoxyanthranilate >98.0%(GC)(T) | 26759-46-6 | 25g | $48 | 2026-04-30 | Buy |
| Usbiological | 283285 | Methyl 2-amino-4,5-dimethoxybenzoate Asreported | 26759-46-6 | 5g | $319 | 2026-06-03 | Buy |
| Usbiological | 283285 | Methyl 2-amino-4,5-dimethoxybenzoate Asreported | 26759-46-6 | 10g | $418 | 2026-06-03 | Buy |
| Usbiological | 283285 | Methyl 2-amino-4,5-dimethoxybenzoate Asreported | 26759-46-6 | 25g | $531 | 2026-06-03 | Buy |
Methyl 2-amino-4,5-dimethoxybenzoate Chemical Properties,Uses,Production
Chemical Properties
Brown crystalline powder
Uses
3-Acetamido-2-hydroxyacetophenone is used in the preparation fo Antitumor Agents in Breast Cancer.
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
26791-93-5
26759-46-6
General procedure for the synthesis of methyl 2-amino-4,5-dimethoxybenzoate from methyl 4,5-dimethoxy-2-nitrobenzoate: 1.9 g (7.2 mmol) of methyl 4,5-dimethoxy-2-nitrobenzoate and 0.2 g of palladium-carbon catalyst were added to a 100 mL round-bottomed flask and dissolved in 50 mL of methanol. Hydrogen was passed into the reaction system and the reaction mixture was stirred at room temperature for 24 hours. The reaction progress was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the brown solid catalyst was removed by filtration. The product was separated and purified by column chromatography (eluent ratio: petroleum ether:ethyl acetate = 10:1, V/V) to afford 1.51 g of the white solid target compound in 88.7% yield with a melting point of 91-93°C. The product was purified by column chromatography (eluent ratio: petroleum ether:ethyl acetate = 10:1, V/V).
References
[1] Patent: CN105037279, 2017, B. Location in patent: Paragraph 0047; 0048
[2] Bioorganic and Medicinal Chemistry Letters, 2014, vol. 24, # 18, p. 4455 - 4459
[3] Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1995, vol. 34, # 10, p. 911 - 913
[4] Justus Liebigs Annalen der Chemie, 1896, vol. 293, p. 190
[5] Journal of the American Chemical Society, 1919, vol. 41, p. 2147
Methyl 2-amino-4,5-dimethoxybenzoate Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Hangzhou Cyanochem Co., Ltd. | +86 17788583750 | sales@cyanochem.com | CHINA | 281 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Baoji Guokang Healthchem Co., Ltd. | +86-0917-3909592 +86-13892490616 | gksales1@gk-bio.com | China | 9050 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
View Lastest Price from Methyl 2-amino-4,5-dimethoxybenzoate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-02-10 | Methyl 2-amino-4,5-dimethoxybenzoate
26759-46-6
|
25KG | 99.8% | 2000KG/th | Zibo Shiji Zhonglian Medical Technology Co., Ltd. | ||
 |
2021-07-13 | Methyl 2-amino-4,5-dimethoxybenzoate
26759-46-6
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2021-07-10 | Methyl 2-amino-4,5-dimethoxybenzoate
26759-46-6
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- Methyl 2-amino-4,5-dimethoxybenzoate
26759-46-6
- $0.00
- 99.8%
- Zibo Shiji Zhonglian Medical Technology Co., Ltd.
-
- Methyl 2-amino-4,5-dimethoxybenzoate
26759-46-6
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- Methyl 2-amino-4,5-dimethoxybenzoate
26759-46-6
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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