1-Acetylimidazole
- CAS No.
- 2466-76-4
- Chemical Name:
- 1-Acetylimidazole
- Synonyms
- NAI;1-(1H-imidazol-1-yl)ethan-1-one;N-ACETYLIMIDAZOLE;1-Imidazol-1-ylethanone;Acetylimidazole;4-ACETYLIMIDAZOLE;1-Acetylimida;N-Acylimidazole;N-ACETYLIMIDAZOL;1-AcetliMidazole
- CBNumber:
- CB9339608
- Molecular Formula:
- C5H6N2O
- Molecular Weight:
- 110.11
- MDL Number:
- MFCD00005287
- MOL File:
- 2466-76-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 1-Acetylimidazole Novabiochem? | 8.51210 | 25G | $48.5 |
| 1-Acetylimidazole Novabiochem? | 8.51210 | 100G | $145 |
| 1-Acetylimidazole Novabiochem® | 8.51210 | 500 g | $443 |
| 1-Acetylimidazole 98% | 157864 | 25g | $58.2 |
| 1-Acetylimidazole 98% | 157864 | 1kg | $855 |
| More product size | |||
| Melting point | 99-105 °C (lit.) |
|---|---|
| Boiling point | 206.4°C (rough estimate) |
| Density | 1.2111 (rough estimate) |
| refractive index | 1.4800 (estimate) |
| storage temp. | 2-8°C |
| solubility | water: soluble50mg/mL, clear, colorless |
| pka | pKa 3.6(H2O,t = 25,I=0.2) (Uncertain) |
| form | Adhering Crystals or Crystalline Powder |
| color | White to beige or light tan |
| Water Solubility | Hydrolyzes in water. Solubility in methanol (almost transparency). |
| Sensitive | Moisture Sensitive |
| BRN | 108425 |
| Stability | Moisture Sensitive |
| InChI | 1S/C5H6N2O/c1-5(8)7-3-2-6-4-7/h2-4H,1H3 |
| InChIKey | VIHYIVKEECZGOU-UHFFFAOYSA-N |
| SMILES | CC(=O)n1ccnc1 |
| CAS DataBase Reference | 2466-76-4(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | ZMP8X1Y11G |
| NIST Chemistry Reference | 1H-Imidazole, 1-acetyl-(2466-76-4) |
| EPA Substance Registry System | 1H-Imidazole, 1-acetyl- (2466-76-4) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | NI3400000 | |||||||||
| F | 10-21 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29332900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
1-Acetylimidazole price More Price(89)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.51210 | 1-Acetylimidazole Novabiochem? | 2466-76-4 | 25G | $48.5 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.51210 | 1-Acetylimidazole Novabiochem? | 2466-76-4 | 100G | $145 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.51210 | 1-Acetylimidazole Novabiochem® | 2466-76-4 | 500 g | $443 | 2026-04-30 | Buy |
| Sigma-Aldrich | 157864 | 1-Acetylimidazole 98% | 2466-76-4 | 25g | $58.2 | 2026-04-30 | Buy |
| Sigma-Aldrich | 157864 | 1-Acetylimidazole 98% | 2466-76-4 | 1kg | $855 | 2026-04-30 | Buy |
1-Acetylimidazole Chemical Properties,Uses,Production
Chemical Properties
white to beige or light tan adhering crystals or
Uses
Relatively specific reagent for tyrosyl residue acetylation. Reagent used in the synthesis of annulated imidazole derivatives.
Uses
Acetylating agent for capping unreacted amino groups in peptide synthesis.
Uses
It is a mild acylating agent and its reactivity can be enhanced by quaternization with, e.g. benzyl bromide. 1-Acetylimidazole was used as acetylation reagent for amino groups. It was also employed for acetylation of histones. It is relatively specific reagent for tyrosyl residue acetylatioa dn a reagent used in the synthesis of annulated imidazole derivatives.
Definition
ChEBI: N-acetylimidazole is a N-acylimidazole.
General Description
Rate of solvolysis of 1-acetylimidazole in acid solutions was evaluated. Reaction of 1-acetylimidazole with orthophosphate and adenosine-5′-phosphate has been reported.
Purification Methods
It is recrystallised from isopropenyl acetate and dried in a vacuum over P2O5. [Riordan & Valee Methods Enzymol 25 500 1972, Beilstein 23/4 V 218.]
1-Acetylimidazole Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Scochem Technology Co., Ltd | +86-021-33758897 +86-13701882790 | sales@scochem.com | China | 1977 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +86-17531190177 | faithe@yan-xi.com | China | 5853 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20120 | 58 |
| Hebei Longbang Technology Co., LTD | +86-18633929156 | admin@hblongbang.com | China | 972 | 58 |
| HebeiShuoshengImportandExportco.,Ltd | +86-18532138899 | L18532138899@163.com | China | 939 | 58 |
| Hubei Lidu New Material Technology Co., Ltd | +86-19307248857 +86-19307248857 | 19307248857@163.com | China | 565 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29812 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 | sales@amoychem.com | China | 6366 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19936 | 58 |
View Lastest Price from 1-Acetylimidazole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-21 | 1-Acetylimidazole
2466-76-4
|
1G | 99% | 20TONS | Hubei Lidu New Material Technology Co., Ltd | ||
 |
2026-07-09 | 1-Acetylimidazole
2466-76-4
|
$1.00-100.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2025-07-29 | 1-Acetylimidazole
2466-76-4
|
$6.00 | 1kg | 99% | 2000KG/Month | HebeiShuoshengImportandExportco.,Ltd |
-
- 1-Acetylimidazole
2466-76-4
- 99%
- Hubei Lidu New Material Technology Co., Ltd
-
- 1-Acetylimidazole
2466-76-4
- $1.00-100.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 1-Acetylimidazole
2466-76-4
- $6.00
- 99%
- HebeiShuoshengImportandExportco.,Ltd
