CD152/FCキメラ, 非細胞傷害性 マウス由來 価格

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CD152/FCキメラ, 非細胞傷害性 マウス由來 化學特性,用途語,生産方法

一般的な説明

The extracellular domain (160 amino acids) of mouse CD152 is fused to mouse IgG2a Fc domain in which mutations to the complement (C1q) and FcγR I binding sites of the Fcγ2a fragment render the Fc fusion protein incapable of direct antibody directed cytotoxicity (ADCC) and complement directed cytotoxicity (CDC).

Biochem/physiol Actions

CD152 (CTLA4), a cell surface glycoprotein expressed at low levels on activated T cells, is a high affinity receptor for the costimulatory molecules CD80 (B7-1) and CD86 (B7-2). A related cell surface glycoprotein, CD28, binds to CD80 and CD86 with lower affinity. The soluble CD152/Fc chimeric fusion protein blocks the B7/CD28 signaling pathway by binding to CD80 and CD86.

CD152/FCキメラ, 非細胞傷害性 マウス由來 上流と下流の製品情報

原材料

準備製品

CD152/FCキメラ, 非細胞傷害性 マウス由來 生産企業(yè)

名前	電話番號	電子メール	國籍	製品カタログ	優(yōu)位度
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51395	80
Merck KGaA	--	ordercn@merckgroup.com	China	6394	58

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• CD152/FC CHIMERA, CYTOLYTIC
• CD152/FC CHIMERA, NON-CYTOLYTIC
• CD152-FC FUSION PROTEIN, HUMAN
• CD152:FC (HUMAN)-MULG FUSION PROTEIN
• CD152/Fc Chimera, Cytolytic from mouse
• CD152/Fc Chimera, Non-cytolytic from mouse
• CTLA4/FC CHIMERA, CYTOLYTIC
• CTLA4/FC CHIMERA, NON-CYTOLYTIC
• CTLA-4:FC (HUMAN)-MULG FUSION PROTEIN
• CTLA-4 MULG FUSION PROTEIN, HUMAN
• CD152/FCキメラ, 非細胞傷害性 マウス由來