N-クロロ-p-トルエンスルホンアミド 化學(xué)特性,用途語,生産方法
定義
本品は、次の化學(xué)式で表される芳香族スルホン酸アミドである。
無機(jī)性値/有機(jī)性値
765/180
解説
クロラミンT，N-クロロ-p-トルエンスルホンアミドナトリウムの商品名。p-トルエンスルホン酸アミドに次亜塩素酸ナトリウムを作用させると得られる．白色の結(jié)晶性粉末．水やアルコールに易溶．強(qiáng)い酸化作用や塩素化作用をもち，殺菌消毒剤として傷口の防腐に用いられる．また，分析試薬としてヒ素(Ⅲ)，アンチモン(Ⅲ)，スズ(Ⅱ)，鉄(Ⅱ)，チオシアン酸塩などの酸化滴定に標(biāo)準(zhǔn)液として用いられる．
化粧品の成分用途
防腐剤、殺菌剤
効能
殺菌消毒薬
説明
The sodium salt of p-toluenesulfochloramide, commonly known as chloramine-T, exerts strong oxidizing action in both acidic and alkaline media and thus has been widely used for the oxidimetric determination of a large number of inorganic and organic substances.
Oxidation of some aldehydes by chloramine-T has been reported to occur quantitatively in an alkaline solution, giving the corresponding acid as the end product. Both direct and indirect methods have been carried out to estimate aldehydes by chloramine-T. Chloramine-T (CAT) is also commonly used in radiolabeling bioactive molecules by halogenation. CAT is used to release radioactive elemental iodine by oxidation of its salts. Unfortunately, CAT is a strong oxidizing agent and can cause significant damage to peptides and proteins. This may lower the yield of the iodination reaction and may produce undesirable side products[1-2].
化學(xué)的特性
white or yellow powder with a chlorine-like odour
使用
This disinfectant is for external use only, it can exterminate bacteria, viruses, fungi, spore. The action principle is that chlorine can sterilize slowly and lastingly, and also can dissolve necrotic tissue, chlorine come from hypochlorous acid which is produced by Chloramine-T solution. Apply to disinfect drinking water container,food,all kind of tableware, fruits and vegetables,and cleaning wound, mucous membrane.
定義
ChEBI: Chloramine T is an organic sodium salt derivative of toluene-4-sulfonamide with a chloro substituent in place of an amino hydrogen. It has a role as a disinfectant, an allergen and an antifouling biocide. It contains a chloro(p-tolylsulfonyl)azanide.
工業(yè)用途
Chloramine-T (Cl-T) is a disinfectant and bactericide. In aquaculture, Cl-T is used as a disinfectant to inactivate viruses and bacteria, and is widely employed to treat bacterial infections of the gills and skin in Atlantic salmon. The US Food and Drug Administration recommends the use of chloramine-T for the treatment of salmonids, administered once daily via static baths or low-flow flushing treatments at a dose of 10–20 mg L?1, for three consecutive days (for intensive treatment) or three treatments every other day[3].
副作用
Chloramine-T is considered safe when used within the specified dosage range. Concentrations of chlorine or chloramine in drinking water of 4 milligrams per litre (mg/L) or 4 parts per million (ppm) or less are considered safe. At these low concentrations, the substance kills harmful bacteria and is unlikely to cause illness. In cases of misuse or excessive dosage, common side effects include respiratory irritation, skin and eye irritation, gastrointestinal discomfort and allergic reactions.
安全性プロファイル
Poison by parenteral and intravenous routes. Human mutagenic data reported. When heated to
decomposition it emits toxic fumes of Cl-,
SOx, Na2O, and NOx. See also
SULFONATES and CHLORIDES.
合成
Chloramine-T is prepared
in 75 – 95 % yield by passing chlorine into a
sodium hydroxide solution of p-toluenesulfonamide. It is a strong electrolyte in acid
solution and a good oxidizing agent in base. It is
fairly soluble in water, and practically insoluble
in benzene, chloroform, and ether. The compound reacts readily with mustard gas to yield
a harmless crystalline sulfimide; chloramine-T
derivatives are being studied as protective agents
against poison gas.
N-クロロ-p-トルエンスルホンアミド 上流と下流の製品情報(bào)
原材料
準(zhǔn)備製品