N-アセチル-Ser-Asp-Lys-Pro-OH
N-アセチル-Ser-Asp-Lys-Pro-OH 物理性質(zhì)
- 沸點(diǎn) :
- 992.0±65.0 °C(predicted)
- 比重(密度) :
- 1.382±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
- 貯蔵溫度 :
- −20°C
- 溶解性:
- Soluble in DMSO
- 酸解離定數(shù)(Pka):
- 3.39±0.20(predicted)
- 外見(jiàn) :
- 個(gè)體
- 色:
- ホワイトからオフホワイト
- 水溶解度 :
- 2mg/mlで水に溶ける
- シーケンス:
- H-Gln-Lys-Leu-Val-Phe-Phe-Ala-OH
安全性情報(bào)
N-アセチル-Ser-Asp-Lys-Pro-OH 価格
もっと(2)
| メーカー |
製品番號(hào) |
製品説明 |
CAS番號(hào) |
包裝 |
価格 |
更新時(shí)間 |
購(gòu)入 |
|
富士フイルム和光純薬株式會(huì)社(wako)
|
W01BCS4016348 |
Ac-Ser-Asp-Lys-Pro-OH |
127103-11-1 |
5mg |
￥32000 |
2024-03-01 |
購(gòu)入 |
|
富士フイルム和光純薬株式會(huì)社(wako)
|
W01BCS4016348 |
Ac-Ser-Asp-Lys-Pro-OH |
127103-11-1 |
25mg |
￥126000 |
2024-03-01 |
購(gòu)入 |
N-アセチル-Ser-Asp-Lys-Pro-OH 化學(xué)特性,用途語(yǔ),生産方法
使用
N-Acetyl-Ser-Asp-Lys-Pro inhibits the entry of pluripotent hemopoietic stem cells into S-phase of the cell cycle and protects against Ara-C lethality in mice. It is a specific substrate for the N-terminal active site of angiotensin converting enzyme, which is responsible for its degradation in vivo.
合成
Fmoc-Pro-OH was coupled to a 2-chlorotriphenylmethyl chloride resin, followed by sequential addition of Lys, Asp, and Ser units via cyclic deprotection (using piperidine/DMF) and coupling (using activating reagents such as TBTU/HOBt). After peptide chain elongation, the N-terminus was acetylated with acetic anhydride. Finally, the peptide was cleaved from the resin using a trifluoroacetic acid (TFA) cleavage reagent, simultaneously removing the side-chain protecting groups. High-purity Goralatide was obtained by ether precipitation and HPLC purification.
N-アセチル-Ser-Asp-Lys-Pro-OH 上流と下流の製品情報(bào)
原材料
準(zhǔn)備製品
N-アセチル-Ser-Asp-Lys-Pro-OH 生産企業(yè)
Global( 165)Suppliers
N-アセチル-Ser-Asp-Lys-Pro-OH スペクトルデータ(1HNMR)
127103-11-1(N-アセチル-Ser-Asp-Lys-Pro-OH)キーワード:
- 127103-11-1
- ACETYL-SER-ASP-LYS-PRO
- AC-SDKP-DELTA
- AcSDKP
Ac-Ser-Asp-Lys-Pro
- REF DUPL: Ac-Ser-Asp-Lys-Pro-OH
- AcSDKP, SteM Cell Proliferation Inhibitor, Goralatide, ThyMosin b4 (1-4)
- Ac-L-Ser-L-Asp-L-Lys-L-Pro-OH
- N-Acetyl-Ser-Asp-Lys-Pro-OH
- N-Ac-Ser-Asp-Lys-Pro-OH
- Acetyl-serinyl-aspartyl-lysinyl-proline
- GORALATIDE
- L-Proline, N-acetyl-L-seryl-D-α-aspartyl-L-lysyl-
- AC-SER-ASP-LYS-PRO-OH USP/EP/BP
- 1-[2-[[2-[(2-acetamido-3-hydroxypropanoyl)amino]-3-carboxypropanoyl]amino]-6-aminohexanoyl]pyrrolidine-2-carboxylic acid
- Ac-Ser-Asp-Lys-Pro-OH (H-1156.0005)
- Ac-SDKP,NAcetylSerAspLysPro,Inhibitor,inhibit,N Acetyl Ser Asp Lys Pro,Angiotensin-converting Enzyme (ACE)
- Thymosin beta4 (1-4)
- AC-SER-ASP-LYS-PRO-O
- N-Acetyl-L-seryl-D-α-aspartyl-L-lysyl-L-proline
- AC-SER-ASP-LYS-PRO-OH
- AC-SER-ASP-LYS-PRO
- Acetyl-SDKP
- AC-SDKP
- SERASPENIDE
- Thymosin β4 (1-4)
- N-アセチル-Ser-Asp-Lys-Pro-OH
- ゴララチド