2-????????
|
|
2-???????? ??
- ???
- 205-210 °C(lit.)
- ?? ?
- 273.17°C (rough estimate)
- ??
- 1.2023 (rough estimate)
- ???
- 1.5810 (estimate)
- ?? ??
- Keep in dark place,Inert atmosphere,Room temperature
- ???
- DMSO(?? ???), ???(?? ???)
- ??? ??
- ??
- ?? ?? (pKa)
- 9.35±0.35(Predicted)
- ??
- ???? ???, ?????
- BRN
- 607592
- ???
- ????. ?? ???, ????????, ?, ? ???, ? ???? ???? ????.
- InChI
- InChI=1S/C8H9NO2/c1-6(10)9-7-4-2-3-5-8(7)11/h2-5,11H,1H3,(H,9,10)
- InChIKey
- ADVGKWPZRIDURE-UHFFFAOYSA-N
- SMILES
- C(NC1=CC=CC=C1O)(=O)C
- CAS ??????
- 614-80-2(CAS DataBase Reference)
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | Xi,Xn | ||
|---|---|---|---|
| ?? ???? ?? | 36/38-22-36/37/38 | ||
| ????? | 26-36-37/39 | ||
| ????(UN No.) | 2811 | ||
| WGK ?? | 3 | ||
| RTECS ?? | AE4025000 | ||
| F ?????? | 1-8 | ||
| TSCA | TSCA listed | ||
| ?? ?? | 6.1(b) | ||
| ???? | III | ||
| HS ?? | 29242995 | ||
| ???? ??? | 11 - Combustible Solids |
2-???????? C??? ??, ??, ??
??? ??
white or light brown powder.soluble in hot water and ethanol, slightly soluble in cold water.??
An Acetaminophen (A161220) impurity.2-Acetamidophenol is used as raw material to manufacture industrial organic chemicals.
Acetaminophen is an analgesic and antipyretic agent and used as a pain reliever to treat headache, muscle aches, and arthritis.
?? ??
Mix 2-Aminophenol , acetic acid and Acetic anhydride (i.e., crystals appear), and then directly heated on the fire until all dissolved, stop heating, cooling, water dilution, precipitation of crystals filtered dry, to 70-80 ℃ of ethanol recrystallization to obtain 2-acetamidophenol.??
ChEBI: 2-acetamidophenol is a member of the class of phenols that is 2-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group. A positional isomer of paracetamol which possesses anti-inflammatory, anti-arthritic and anti-platelet aggregation properties. It has a role as a platelet aggregation inhibitor, an anti-inflammatory agent, a xenobiotic metabolite, an apoptosis inducer, an antineoplastic agent and an antirheumatic drug. It is a member of phenols and a member of acetamides.?? ??
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.Purification Methods
Recrystallise it from water, EtOH or Est aqueous EtOH. [Beilstein 13 H 370, 13 I 113, 13 II 171, 13 III 778.]2-???????? ?? ?? ? ???
???
?? ??
2-???????? ?? ??
???( 361)?? ??
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|---|---|---|---|---|---|
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