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1163-36-6
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???(??):
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Clemizole hydrochloride
???(??):
CLEMIZOLE HCL;p48;CS-1763;allercur;allercurehydrochloride;LABOTEST-BB LT00453174;CLEMIZOLE HYDROCHLORIDE;Clemizole hydrochloride, >=98%;Clemizole hydrochloride, 10 mM in DMSO;1-(P-CHLOROBENZYL)-2-(1-PYRROLIDINYLMETHYL)-BENZIMIDAZOL
CBNumber:
CB0484200
???:
C19H21Cl2N3
??? ??:
362.3
MOL ??:
1163-36-6.mol
MSDS ??:
SDS

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???
239-241°
?? ??
Inert atmosphere,2-8°C
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H2O: ???2mg/mL, ??(???)
??? ??
??
??
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16.84mg/L at 25℃
Merck
14,2346
InChI
InChI=1S/C19H20ClN3.ClH/c20-16-9-7-15(8-10-16)13-23-18-6-2-1-5-17(18)21-19(23)14-22-11-3-4-12-22;/h1-2,5-10H,3-4,11-14H2;1H
InChIKey
DNFMJYXRIMLMBZ-UHFFFAOYSA-N
SMILES
N1(CC2C=CC(Cl)=CC=2)C(CN2CCCC2)=NC2C=CC=CC1=2.Cl
LogP
1.99
CAS ??????
1163-36-6(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xn
?? ???? ?? 22
????? 36
WGK ?? 3
RTECS ?? DD6730000
HS ?? 2933.99.8290
???? ??? 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? P264, P270, P301+P312, P330, P501
??????:
NFPA 704
0
1 0

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Clemizole Hydrochloride inhibits Hepatitis C RNA replication in cell culture through the suppression of the binding between the nonstructural protein 4B and the viral RNA genome with little toxicity for the host cell. Clemizole Hydrochloride is also a potent inhibitor of transient receptor potential channel TRPC5.

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