ChemicalBook >?? ???? >(R)-(-)-1,4-?????-2,6-???-4-(3-?????)-3,5-?????????????????

(R)-(-)-1,4-?????-2,6-???-4-(3-?????)-3,5-?????????????????

(R)-(-)-1,4-?????-2,6-???-4-(3-?????)-3,5-????????????????? ??? ???

?? ??:: 76093-33-9

???:: (R)-(-)-1,4-?????-2,6-???-4-(3-?????)-3,5-?????????????????

???(??):: (R)-(-)-1,4-?????-2,6-???-4-(3-?????)-3,5-?????????????????

???:: (R)-(-)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid Monomethyl Ester

???(??):: Benidipine Impurity 37;(R)-Lercanidipine EP Impurity A;(-)-1,4-Dihydro-5-(methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylic Aci;(R)-5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid;(-)-1,4-Dihydro-5-(methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylic Acid;(4R)-5-(methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid;(R)-(-)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid monomethyl es;(4r)-1,4-dihydro-2,6-dimethyl-3-methyloxycarbonyl-4-(3-nitrophenyl)-pyridine-5-carboxylic acid;3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-diMethyl-4-(3-nitrophenyl)-, 3-Methyl ester, (4R)-;(4R)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-Pyridinedicarboxylic acid, 3-methyl ester

CBNumber:: CB21175367

???:: C16H16N2O6

??? ??:: 332.31

MOL ??:: 76093-33-9.mol

?? ?? 41

(R)-(-)-1,4-?????-2,6-???-4-(3-?????)-3,5-????????????????? ??

???: 168-172 °C

?? ?: 505.0±50.0 °C(Predicted)

??: 1.345±0.06 g/cm3(Predicted)

?? ??: Sealed in dry,Room Temperature

???: DMSO(?? ???), ???(?? ???, ??)

??? ??: ??

??? ??: ??? ??

?? ?? (pKa): 1.66±0.70(Predicted)

??: ?? ????? ?????

CAS ??????: 76093-33-9

?? ? ?? ??
?? ? ???? ?? (GHS)

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	?? ??	P- ??
H303	??? ??? ? ??	?? ?? ?? - ??	?? 5			P312
H320	?? ??? ???	?? ? ?? ?? ??? ??	?? 2B	??		P264, P305+P351+P338,P337+P313

??????:

P264	?? ??? ?? ??? ????.
P264	?? ??? ?? ??? ????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P312	???? ??? ????(??)? ??? ????.
P337+P313	?? ?? ??? ???? ???? ??· ??? ????.

(R)-(-)-1,4-?????-2,6-???-4-(3-?????)-3,5-????????????????? C??? ??, ??, ??

??? ??

Light-Yellow Solid

??

(R)-(-)-1,4-Dihydro-2,6-diMethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid MonoMethyl Ester is used in the prevention and therapy of atherosclerotic degradation of arterial walls.

(R)-(-)-1,4-?????-2,6-???-4-(3-?????)-3,5-????????????????? ?? ?? ? ???

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(R)-(-)-1,4-?????-2,6-???-4-(3-?????)-3,5-????????????????? ?? ??

???( 41)?? ??

???	??	???	??	?? ?	??
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(R)-(-)-1,4-?????-2,6-???-4-(3-?????)-3,5-????????????????? ?? ??:

S(+)-??????? Benidipine Benidipine hydrochloride Barnidipine Niludipine Barnidipine hydrochloride M-NIFEDIPINE (R)-Lercanidipine Hydrochloride (+)-Nitrendipine (-)-Nitrendipine (R)-(-)-NIGULDIPINE HYDROCHLORIDE AURORA 4028 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophen yl)-1-(phenylmethyl)-, diethyl ester AURORA KA-7222 AURORA 11958 AURORA 3705 AURORA 3481

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