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??????

??????
?????? ??? ???
?? ??:
118-56-9
???:
??????
???(??):
??????
???:
Homosalate
???(??):
HMS;HOMOMENTHYL SALICYLATE;Heliopan;Homosalat;3,3,5-TRIMETHYLCYCLOHEXYL SALICYLATE;Benzoicacid,2-hydroxy-,3,3,5-trimethylcyclohexylester;HELIOPHAN;omosalate;HOMOSALATE;Coppertone
CBNumber:
CB2203124
???:
C16H22O3
??? ??:
262.34
MOL ??:
118-56-9.mol
MSDS ??:
SDS

?????? ??

?? ?
161-165°C (12 torr)
??
1.05
???
0.015Pa at 25℃
???
n20 1.516 to 1.518
???
169 - 173℃
?? ??
Inert atmosphere,Room Temperature
???
????? (?? ???), DMSO (?? ???)
??? ??
Liquid
?? ?? (pKa)
8.10±0.30(Predicted)
??
??
??
100.00?%. ?? ??
???
26°C?? <0.1g/100mL
BRN
2731604
??? ?? ??
??
??? ???
??? ??
LogP
6.27 at 25℃
CAS ??????
118-56-9(CAS DataBase Reference)
NIST
Homosalate(118-56-9)
EPA
3,3,5-Trimethylcyclohexyl salicylate (118-56-9)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
?? ???? ?? 36/37/38
????? 26-36/39
WGK ?? 2
TSCA TSCA listed
HS ?? 29182300
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ??
??????:
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P321 (…) ??? ???.
P332+P313 ?? ??? ??? ???? ??· ??? ????.
P362 ??? ??? ?? ?? ?? ?????
NFPA 704
0
2 0

?????? C??? ??, ??, ??

??

Homosalate is an organic compound that belongs to a class of chemicals called salicylates. Salicylates prevent direct skin exposure to the sun’s harmful rays by absorbing ultraviolet (UV) light. Homosalate specifically absorbs short-wave UVB rays, associated with DNA damage and an increased risk of skin cancer. It is a widely used chemical in sunscreens and skin care products with SPF. However, Homosalate is a potential endocrine disruptor and studies in cells suggest it may impact hormones. In addition to direct health concerns following homosalate exposure, the chemical may also enhance the absorption of pesticides in the body.

??? ??

Liquid.

??

homosalate is a chemical uVB absorber included in the FDA’s Category I Sunscreen Chemical list. Its approved usage level is 4 to 15 percent by the FDA and 10 percent by the european union’s Cosmetic Directive.

??

A homolog of menthyl salicylate.

?? ??

Viscous or light yellow to slightly tan liquid or oil.

??? ?? ??

Homosalate will hydrolyze under basic conditions. . Insoluble in water.

?? ???

An ester and a phenol. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.

????

Homosalate is probably combustible.

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