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Bromhexine hydrochloride

Bromhexine hydrochloride ??? ???
?? ??:
611-75-6
???:
Bromhexine hydrochloride
???(??):
BROMHEXINE HCL;BREVISCAPINE;Bromexine Hcl;BROMOHEXINE HYDROCHLORIDE;bisolvon;Cofmesin;Hapysuol;Coughtimi;bromessina;Bisopollon
CBNumber:
CB3249453
???:
C14H21Br2ClN2
??? ??:
412.59
MOL ??:
611-75-6.mol
MSDS ??:
SDS

Bromhexine hydrochloride ??

???
240-244 °C
?? ??
Sealed in dry,Room Temperature
???
?? ?? ?? ????, ???? ??????? ?? ?????.
??? ??
??
??
??~?? ???
?? ??(λmax)
307nm(Decane)(lit.)
Merck
14,1391
BRN
4848376
InChI
InChI=1S/C14H20Br2N2.ClH/c1-18(12-5-3-2-4-6-12)9-10-7-11(15)8-13(16)14(10)17;/h7-8,12H,2-6,9,17H2,1H3;1H
InChIKey
UCDKONUHZNTQPY-UHFFFAOYSA-N
SMILES
C1(C=C(C=C(Br)C=1N)Br)CN(C)C1CCCCC1.Cl
LogP
5.081 (est)
CAS ??????
611-75-6(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xn
?? ???? ?? 20/21/22-36/37/38
????? 22-24/25-36-26
WGK ?? 2
RTECS ?? XS9950000
HS ?? 29215990
???? ??? 11 - Combustible Solids
???? ?? KE-01287
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? P264, P270, P301+P312, P330, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ??
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

Bromhexine hydrochloride C??? ??, ??, ??

??

Bromhexine Hydrochloride is the hydrochloride salt form of bromhexine, a secretolytic, with mucolytic activity. Upon administration, bromhexine increases lysosomal activity and enhances hydrolysis of acid mucopolysaccharide polymers in the respiratory tract. This increases the production of serous mucus in the respiratory tract, which makes the phlegm thinner and decreases mucus viscosity. This contributes to its secretomotoric effect, and allows the cilia to more easily transport the phlegm out of the lungs. This clears mucus from the respiratory tract and may aid in the treatment of respiratory disorders associated with abnormal viscid mucus, excessive mucus secretion and impaired mucus transport.

??? ??

White Solid

??

Bromhexine hydrochloride is a mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus.
Bromhexine hydrochloride belongs to the group of expectorants (mucoactive agents). The active substance has a secretolytic effect. It is used for the treatment of strong cough, e.g. triggered by a bronchitis.

??

ChEBI: A hydrochloride resulting from the reaction of equimolar amounts of bromhexine and hydrogen chloride. It is used as a mucolytic for the treatment of respiratory disorders associated with productive cough (i.e. a cough characterised by the production of spu um).

?? ??

Bromhexine hydrochloride is a bronchial mucolytic.

Bromhexine hydrochloride ?? ?? ? ???

???

?? ??


Bromhexine hydrochloride ?? ??

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Bromhexine hydrochloride ?? ??:

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