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SCR7

SCR7 ??? ???

?? ??:: 1533426-72-0

???:: SCR7

???(??):: SCR7;CS-1733;SCR7 (SCR-7);SCR7 USP/EP/BP;5,6-bis((E)-benzylideneamino)-2-mercaptopyrimidin-4-ol;5,6-bis((E)-benzylideneamino)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one;2,3-Dihydro-5,6-bis[(E)-(phenylmethylene)amino]-2-thioxo-4(1H)-pyrimidinone;4(1H)-Pyrimidinone, 2,3-dihydro-5,6-bis[(E)-(phenylmethylene)amino]-2-thioxo-;5,6-bis[(E)-(phenylmethylidene)amino]-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one

CBNumber:: CB32735396

???:: C18H14N4OS

??? ??:: 334.39

MOL ??:: 1533426-72-0.mol

?? ?? 88

SCR7 ??

???: 206-208°C

??: 1.27±0.1 g/cm3(Predicted)

?? ??: Store at -20°C

???: DMSO(?? ???), ???(?? ???)

??? ??: ??

??? ??: ??? ??

?? ?? (pKa): 7.93±0.25(Predicted)

??: ???

?? ? ?? ??
?? ? ???? ?? (GHS)

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	P- ??
H315	??? ??? ???	????? ?? ?????	?? 2	??	P264, P280, P302+P352, P321,P332+P313, P362
H319	?? ?? ??? ???	?? ? ?? ?? ??? ??	?? 2A	??	P264, P280, P305+P351+P338,P337+P313P
H335	?? ???? ??? ? ??	?? ???? ?? - 1? ??;???? ??	?? 3	??

??????:

P261	??·?·??·???·??·...·????? ??? ????.
P264	?? ??? ?? ??? ????.
P264	?? ??? ?? ??? ????.
P271	?? ?? ??? ? ?? ???? ?????.
P280	????/???/???/?????? ?????.
P302+P352	??? ??? ??? ?? ????.
P304+P340	???? ??? ??? ?? ??? ??? ???? ?? ??? ??? ????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P312	???? ??? ????(??)? ??? ????.
P321	(…) ??? ???.
P332+P313	?? ??? ??? ???? ??· ??? ????.
P337+P313	?? ?? ??? ???? ???? ??· ??? ????.
P403+P233	??? ??? ? ?? ?? ??? ???? ?????.
P405	???? ?????.
P501	...? ??? / ??? ?? ???.

NFPA 704

	0
2		0

SCR7 C??? ??, ??, ??

??

SCR7 is an anti cancer molecule that selectively inhibits one of the DNA double strand break (DSB) repair pathways, non-homologous end joining (NHEJ).

SCR7 ?? ?? ? ???

???

?? ??

SCR7 ?? ??

???( 88)?? ??

???	??	???	??	?? ?	??
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SCR7 ?? ??:

KU-55933 (ATM Kinase Inhibitor) Trametinib BIRB 796 (Doramapimod) PD 0332991 HCl Veliparib Olaparib

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