3,4-DIHYDROQUINOLIN-2(1H)-ONE
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3,4-DIHYDROQUINOLIN-2(1H)-ONE ??
- ???
- 165-167 °C (lit.)
- ?? ?
- 267.28°C (rough estimate)
- ??
- 1.1135 (rough estimate)
- ???
- 1.5200 (estimate)
- ?? ??
- Keep in dark place,Sealed in dry,Room Temperature
- ???
- DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:6): 0.14 mg/ml
- ??? ??
- ??? ??
- ?? ?? (pKa)
- 14.76±0.20(Predicted)
- ??
- ???
- ???
- ?? ?? ?????.
- ??
- Light Sensitive
- Merck
- 13,4800
- InChI
- InChI=1S/C9H9NO/c11-9-6-5-7-3-1-2-4-8(7)10-9/h1-4H,5-6H2,(H,10,11)
- InChIKey
- TZOYXRMEFDYWDQ-UHFFFAOYSA-N
- SMILES
- N1C2=C(C=CC=C2)CCC1=O
- CAS ??????
- 553-03-7(CAS DataBase Reference)
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | Xn,Xi | ||
|---|---|---|---|
| ?? ???? ?? | 22-36/37/38-43 | ||
| ????? | 26-36/37 | ||
| ????(UN No.) | 2811 | ||
| WGK ?? | 2 | ||
| ?? ?? ?? | Irritant | ||
| ?? ?? | 6.1(b) | ||
| ???? | III | ||
| HS ?? | 29337900 | ||
| ???? ??? | 11 - Combustible Solids | ||
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 Skin Sens. 1 STOT SE 3 |
3,4-DIHYDROQUINOLIN-2(1H)-ONE C??? ??, ??, ??
??? ??
Off-white crystalline powder??
3,4-Dihydro-2-(1H)-quinolinone may be employed as medium supplement in the culture medium of Pseudomonas ayucida during enrichment culture experiments. It is used to prepare potent bicyclic peptide deformylase inhibitors with antibacterial effects. It is also used to synthesize substituted iminopiperidines as inhibitors of human nitric oxide synthase isoforms.?? ??
Series of 3,4-dihydro-2(1H)-quinolinone derivatives having sigma-1 receptor (σ1R) antagonist activity have been synthesized. 3,4-dihydro-2((1)H)-quinolinones have been synthesized using N-(1′-alkoxy)cyclopropyl-2-haloanilines as starting reagent. Cyclopropane ring expansion in the presence of palladium catalyst is the major step involved in the synthesis. Library of 3,4-dihydro-2(1H)-quinolinones have been synthesized through the rearrangement of β-lactam intermediates on the solid-phase3,4-DIHYDROQUINOLIN-2(1H)-ONE ?? ?? ? ???
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3,4-DIHYDROQUINOLIN-2(1H)-ONE ?? ??
???( 200)?? ??
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3,4-DIHYDROQUINOLIN-2(1H)-ONE ?? ??:
3,7-????-8-??????? ????????? ????? ?????
Tetrahydro-4H-pyran-4-one
Naringin dihydrochalcone
6-Hydroxy-2(1H)-3,4-dihydroquinolinone
Epiandrosterone acetate
Dehydroepiandrosterone
3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone
7-HYDROXY-1,2,3,4-TETRAHYDROQUINOLIN-2-ONE
3,4-DIHYDROQUINOLIN-2(1H)-ONE
AURORA KA-3413
AURORA KA-6039
AURORA KA-5523
1-BUTYL-3-CHLORO-3-METHYL-1,2,3,4-TETRAHYDROQUINOLINE-2,4-DIONE
3-BENZYL-1-BUTYL-3-CHLORO-1,2,3,4-TETRAHYDROQUINOLINE-2,4-DIONE
AURORA KA-3185