ChemicalBook >?? ???? >4'-???????????-9??-?????????

4'-???????????-9??-?????????

4'-???????????-9??-????????? ??? ???

?? ??:: 23363-35-1

???:: 4'-???????????-9??-?????????

???(??):: 4'-???????????-9??-?????????

???:: 4'-demethylepipodophyllotoxin-9 beta-glucopyranoside

???(??):: Lignan P;Etoposide Impurity D;Etoposide EP Impurity D;Etoposide EP impurity 1;FOVRGQUEGRCWPD-MWRKKXAJSA-N;Etoposide EP Impurity D (Lignan P);4’-demethylepipodophyllotoxin-β-D-glucoside;4'-Demethyl epigentrobinotoxin-β-D-glucoside;Etoposide Impurity 4 (Etoposide EP Impurity D);4'-Demethylepipodophyllotoxin β-D-glucopyranoside

CBNumber:: CB61364686

???:: C27H30O13

??? ??:: 562.52

MOL ??:: 23363-35-1.mol

?? ?? 79

4'-???????????-9??-????????? ??

???: 262-264 °C(Solv: methanol (67-56-1))

?? ?: 808.2±65.0 °C(Predicted)

??: 1.62±0.1 g/cm3(Predicted)

?? ??: -20°C Freezer, Under Inert Atmosphere

???: DMSO (?? ???), ???(?? ???,??, ??? ??)

??? ??: ??

??? ??: ??? ??

?? ?? (pKa): 9.94±0.40(Predicted)

??: ???? ?????

?? ? ?? ??
?? ? ???? ?? (GHS)

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	P- ??
H302	??? ???	?? ?? ?? - ??	?? 4	??	P264, P270, P301+P312, P330, P501
H315	??? ??? ???	????? ?? ?????	?? 2	??	P264, P280, P302+P352, P321,P332+P313, P362
H319	?? ?? ??? ???	?? ? ?? ?? ??? ??	?? 2A	??	P264, P280, P305+P351+P338,P337+P313P
H335	?? ???? ??? ? ??	?? ???? ?? - 1? ??;???? ??	?? 3	??

??????:

P261	??·?·??·???·??·...·????? ??? ????.
P264	?? ??? ?? ??? ????.
P264	?? ??? ?? ??? ????.
P270	? ??? ??? ??? ???, ???? ???? ???.
P271	?? ?? ??? ? ?? ???? ?????.
P280	????/???/???/?????? ?????.
P302+P352	??? ??? ??? ?? ????.
P304+P340	???? ??? ??? ?? ??? ??? ???? ?? ??? ??? ????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P330	?? ?????.
P403+P233	??? ??? ? ?? ?? ??? ???? ?????.
P405	???? ?????.
P501	...? ??? / ??? ?? ???.

4'-???????????-9??-????????? C??? ??, ??, ??

??

Lignan P, is a metabolite of Etoposide (E933750), which is a DNA topoisomerase II inhibitor. Semi-synthetic derivative of podophyllotoxin, related structurally to Teniposide. It is also an Antineoplastic.

4'-???????????-9??-????????? ?? ?? ? ???

???

?????

?? ??

4'-???????????-9??-????????? ?? ??

???( 79)?? ??

???	??	???	??	?? ?	??
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4'-???????????-9??-????????? ?? ??:

????? Teniposide Etoposide impurity O Etoposide EP Impurity I Etoposide EP Impurity Q 4'-deMethyldehydropodophyllotoxin Etoposide EP Impurity H Etoposide EP Impurity A Etoposide EP Impurity J 4'-Demethylpodophyllotoxin α-Etoposide Etoposide Impurity B Podophyllotoxin 4'-Demethylepipodophyllotoxin Etoposide phosphate 4'-demethylepipodophyllotoxin-9 beta-glucopyranoside TAFLUPOSIDE ETOPOSIDE, [14C]-

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