EMBELIN
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EMBELIN ??
- ???
- 142-143°C
- ?? ?
- 356.15°C (rough estimate)
- ??
- 1.131
- ???
- 1.4230 (estimate)
- ?? ??
- Keep in dark place,Inert atmosphere,2-8°C
- ???
- DMSO: >10mg/mL
- ??? ??
- ??
- ??? ??
- ??? ??
- ?? ?? (pKa)
- 2.84±0.50(Predicted)
- ??
- ?? ???
- ??
- Light Sensitive
- ???
- ??? ?? ?????? 1? ?? ??????. DMSO ?? ??? ??? -20°C?? ?? 1?? ?? ??? ? ????.
- InChI
- 1S/C17H26O4/c1-2-3-4-5-6-7-8-9-10-11-13-16(20)14(18)12-15(19)17(13)21/h12,18,21H,2-11H2,1H3
- InChIKey
- IRSFLDGTOHBADP-UHFFFAOYSA-N
- SMILES
- CCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O
- LogP
- 5.024 (est)
??
| WGK ?? | 3 | ||
|---|---|---|---|
| RTECS ?? | DK4230000 | ||
| ???? ??? | 11 - Combustible Solids | ||
| Hazard Classifications | Repr. 2 |
EMBELIN C??? ??, ??, ??
??? ??
Orange Solid??
ChEBI: A member of the class of dihydroxy-1,4-benzoquinones that is 2,5-dihydroxy-1,4-benzoquinone which is substituted by an undecyl group at position 3. Isolated from Lysimachia punctata and Embelia ribes, it exhibits antimicrobial, an ineoplastic and inhibitory activity towards hepatitis C protease.???? ??
Cell-permeable, non-peptide inhibitor of X-linked inhibitor of apoptosis (XIAP) (IC 50 = 4.1 μ M in competition binding assay with Smac peptide); binds to the BIR3 domain, preventing XIAP interaction with caspase-9 and Smac. Inhibits cell growth, induces apoptosis and activates caspase-9 in prostate cancer cells (IC 50 4-6 μ M), but has a weaker effect on normal prostate cells (IC 50 = 19-20 μ M). Overcomes the protective effect of XIAP on apoptosis in XIAP-transfected Jurkat cells. Anti-tumor, analgesic and anti-inflammatory in vivo .EMBELIN ?? ?? ? ???
???
?? ??
EMBELIN ?? ??
???( 234)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 33024 | 60 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3619 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 |
scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +86-18080483897 |
sales@biopurify.com | China | 4616 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 |
ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| career henan chemical co | +86-0371-86658258 |
factory@coreychem.com | China | 29792 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 +86-17392581500 |
1015@dideu.com | China | 3861 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 |
sales@chemnorm.com | CHINA | 2935 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 |
marketing@targetmol.com | United States | 32468 | 58 |
| Hubei Ipure Biology Co., Ltd | +8618062405514 |
ada@ipurechemical.com | China | 10236 | 58 |
EMBELIN ?? ??:
EMBELIN
EMBELIN(P),EMBELIN(RG)
2-HYDROXY-5-METHOXY-3-PENTADECYL-[1,4]BENZOQUINONE
2-HYDROXY-5-METHOXY-3-UNDECYL-[1,4]BENZOQUINONE
2,5-DIHYDROXY-3-PENTADECYL-[1,4]BENZOQUINONE
ACETIC ACID 4-ACETOXY-3,6-DIOXO-5-UNDECYL-CYCLOHEXA-1,4-DIENYL ESTER
2-HYDROXY-5-METHOXY-3-TRIDECYL-[1,4]BENZOQUINONE
2,5-DIHYDROXY-3-METHYL-6-NONADECYL-[1,4]BENZOQUINONE
2,5-DIMETHOXY-3-METHYL-6-((E)-NONADEC-14-ENYL)-[1,4]BENZOQUINONE
2,5-DIMETHOXY-3-METHYL-6-NONADECYL-[1,4]BENZOQUINONE
ACETIC ACID 4-ACETOXY-2-METHYL-5-((E)-NONADEC-14-ENYL)-3,6-DIOXO-CYCLOHEXA-1,4-DIENYL ESTER
ILIMAQUINONE
MAESAQUINONE
RAPANONE
ACETIC ACID 4-HYDROXY-2-METHYL-5-((E)-NONADEC-14-ENYL)-3,6-DIOXO-CYCLOHEXA-1,4-DIENYL ESTER
2,5-DIMETHOXY-3-UNDECYL-[1,4]BENZOQUINONE
ACETIC ACID 4-HYDROXY-3,6-DIOXO-5-UNDECYL-CYCLOHEXA-1,4-DIENYL ESTER
2-HYDROXY-5-METHOXY-6-METHYL-3-((E)-NONADEC-14-ENYL)-[1,4]BENZOQUINONE