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7-Nitroindole-2-carboxylic acid

7-Nitroindole-2-carboxylic acid ??? ???
?? ??:
6960-45-8
???:
7-Nitroindole-2-carboxylic acid
???(??):
7-NITRO-1H-INDOLE-2-CARBOXYLIC ACID;7-NO2-ICA;NSC 69877;CRT0044876;7-Nitro-1H-indoL;CRT0044876, >=97%;TIMTEC-BB SBB003487;NSC 69877,7-NO2-ICA;CRT0044876, 10 mM in DMSO;2-Carboxy-7-nitro-1H-indole
CBNumber:
CB7682546
???:
C9H6N2O4
??? ??:
206.15
MOL ??:
6960-45-8.mol
MSDS ??:
SDS

7-Nitroindole-2-carboxylic acid ??

???
260-261 °C
?? ?
344.99°C (rough estimate)
??
1.4588 (rough estimate)
???
1.5570 (estimate)
?? ??
Keep in dark place,Sealed in dry,2-8°C
???
DMSO: >20mg/mL
??? ??
??? ??
?? ?? (pKa)
4.03±0.30(Predicted)
??
Light yellow to yellow
???
???
InChI
1S/C9H6N2O4/c12-9(13)6-4-5-2-1-3-7(11(14)15)8(5)10-6/h1-4,10H,(H,12,13)
InChIKey
BIUCOFQROHIAEO-UHFFFAOYSA-N
SMILES
OC(=O)c1cc2cccc([N+]([O-])=O)c2[nH]1
CAS ??????
6960-45-8(CAS DataBase Reference)
EPA
1H-Indole-2-carboxylic acid, 7-nitro- (6960-45-8)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xn,Xi
?? ???? ?? 36/37/38-21/22-43-36
????? 36/37/39-26-22-36/37
WGK ?? 3
TSCA TSCA listed
?? ?? IRRITANT
HS ?? 2933998090
???? ??? 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Resp. Sens. 1
????(GHS): Health Hazard (GHS08)
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H334 ?? ? ????? ??, ?? ?? ?? ?? ?? ??? ? ?? ??? ??? ?? ?? 1 ?? P261, P285, P304+P341, P342+P311,P501
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P342+P311 ??? ??? ???? ????(??)? ??? ????.
NFPA 704
1
2 0

7-Nitroindole-2-carboxylic acid C??? ??, ??, ??

??? ??

brown powder

??

7-Nitro-1H-indole-2-carboxylic Acid is a potent and selective APE1 inhibitor, which at low micromolar concentrations inhibits the AP endonuclease, 3''-phosphodiesterase and 3''-phosphatase activities of APE1 .

7-Nitroindole-2-carboxylic acid ?? ?? ? ???

???

?? ??


7-Nitroindole-2-carboxylic acid ?? ??

???( 181)?? ??
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7-Nitroindole-2-carboxylic acid ?? ??:

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