????????????
|
|
???????????? ??
- ???
- −32 °C(lit.)
- ?? ?
- 117-123 °C133 mm Hg(lit.)
- ??
- 1.07 g/mL at 25 °C(lit.)
- ???
- n
20/D 1.451(lit.)
- ???
- 167 °F
- ?? ??
- Inert atmosphere,2-8°C
- ???
- ?????, ???(??)? ???
- ??? ??
- ??
- ?? ?? (pKa)
- -1.85±0.70(Predicted)
- ??
- ???
- Specific Gravity
- 1.070
- ???
- ?? ??
- ??
- Moisture Sensitive
- BRN
- 506687
- ???
- ??? ???
- InChI
- 1S/C5H10ClNO/c1-3-7(4-2)5(6)8/h3-4H2,1-2H3
- InChIKey
- OFCCYDUUBNUJIB-UHFFFAOYSA-N
- SMILES
- CCN(CC)C(Cl)=O
- CAS ??????
- 88-10-8(CAS DataBase Reference)
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | Xn | ||
|---|---|---|---|
| ?? ???? ?? | 20/22-36/37/38-40 | ||
| ????? | 26-36/37 | ||
| ????(UN No.) | UN 3265 8/PG 3 | ||
| WGK ?? | 1 | ||
| RTECS ?? | FD4025000 | ||
| TSCA | TSCA listed | ||
| ?? ?? | 8 | ||
| ???? | II | ||
| HS ?? | 29241990 | ||
| ???? ??? | 10 - Combustible liquids | ||
| Hazard Classifications | Acute Tox. 4 Inhalation Acute Tox. 4 Oral Carc. 2 Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
||
| ?? ?? ??? | 88-10-8(Hazardous Substances Data) |
???????????? C??? ??, ??, ??
??? ??
clear yellow to brownish liquid??
It is used in the production of pharma ingredients. It is a reagent in the synthesis of S-Methyl-N,N-diethylthiocarbamate Sulfoxide, which is an oxygenated metabolite of Disulfiram (Antabuse) that is capable of in vitro inactivation of liver mitochondrial aldehyde dehydrogenase.Toxicology
The median lethal dose (LD50) upon oral administration to rats is about 200 mg/kg. The compound is irritating to skin and eyes. The inhalation of an atmosphere saturated with its vapors at 20℃ is lethal to rats after 3 h. Diethylcarbamoyl chloride has proved to be mutagenic on E. coli strains in mutagenicity tests. It is weakly mutagenic in high doses in the Ames test. In view of these results and on account of the structural similarity to dimethylcarbamoyl chloride, a carcinogenic potential cannot be ruled out. The MAK commission has listed this substance in group III B.Safety Profile
Suspected carcinogen with experimental carcinogenic data. Moderately toxic by intraperitoneal route. Mutation data reported. Reacts with water or steam to produce toxic and corrosive fumes. When heated to decomposition it emits highly toxic fumes of Cl and NOx. See also CARBATMATES and CHLORIDES.???????????? ?? ?? ? ???
???
??(??)
??????
METALLURGICAL COKE
??????????
2(1H)-??????????????,3,4-????-(9CI)
?????????????
???????????????
S-??-N,N-???????????
?? ??
???????????? ?? ??
???( 289)?? ??
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|---|---|---|---|---|---|
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