Fmoc-His(Trt)-OH
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Fmoc-His(Trt)-OH ??
- ???
- 150-155 °C(lit.)
- ??
- +86.0 °(D/25)(c=5%inCHCl3)
- ?? ?
- 811.7±65.0 °C(Predicted)
- ??
- 1.24±0.1 g/cm3(Predicted)
- ???
- 97 ° (C=5, CHCl3)
- ?? ??
- 2-8°C
- ???
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- ??? ??
- ??
- ?? ?? (pKa)
- 3.06±0.10(Predicted)
- ??
- ???? ?????
- ?? ??
- [α]/D 87±5°, c = 1 in chloroform
- ???
- ?? ?? ?????.
- ??
- Moisture Sensitive
- BRN
- 5204720
- ?? ??
- ???? ??
- InChIKey
- XXMYDXUIZKNHDT-QNGWXLTQSA-N
- SMILES
- OC(=O)[C@H](Cc1cn(cn1)C(c2ccccc2)(c3ccccc3)c4ccccc4)NC(=O)OCC5c6ccccc6-c7ccccc57
- CAS ??????
- 109425-51-6(CAS DataBase Reference)
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | Xi | ||
|---|---|---|---|
| ?? ???? ?? | 36/37/38 | ||
| ????? | 26-24/25 | ||
| WGK ?? | 3 | ||
| F ?????? | 10-21 | ||
| HS ?? | 2933 29 90 | ||
| ???? ??? | 11 - Combustible Solids |
Fmoc-His(Trt)-OH C??? ??, ??, ??
??? ??
White to off-white solid powder, soluble in water but poorly soluble in ethanol and insoluble in ether. Its structure contains a unique imidazole unit. The imidazole group can form a coordination compound with Fe2+ or other metal ions to promote the absorption of iron, so it can be used to prevent and treat anemia.??
Fmoc-His(Trt)-OH is used in the synthesis and application of Fmoc-His(3-Bum)-OH.?? ??
Fmoc-His(Trt)-OH has fmoc group to protect -αNH2, it can be used as a building block in solid-phase peptide synthesis (SPPS).Fmoc-His(Trt)-OH ?? ?? ? ???
???
?? ??
Fmoc-His(Trt)-OH ?? ??
???( 553)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
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Fmoc-His(Trt)-OH ?? ??:
1-[[(9H-???-9-????)???]??]-2,5-?????? 9-??????? ????? L-(-) ???? ???????? ??-????
L-Fmoc-Aspartic acid alpha-tert-butyl ester
Trityl candesartan
Nalpha-Fmoc-Ndelta-trityl-L-glutamine
Trityl Irbesartan
Trityl candesartan cilexetil
Fmoc-Lys(Boc)-OH
Fmoc-Asp(OtBu)-OH
Fmoc-Phe-OH
N-Fmoc-N'-trityl-D-histidine
Fmoc-D-Asn(Trt)-OH
N-Fmoc-N'-tosyl-L-arginine
N-Fmoc-S-trityl-D-cysteine
N-Boc-N'-trityl-L-glutamine