???? ??

???? C??? ??, ??, ??

????

? (1) ??? ? ????? : ? ?? 2.0g? ?? ????? ??? ? 40mL? ?? ?? ?? ???????? 10mL? ??? 0℃? ??? ???????? 3??? ??? ??? ??? ???.

?????① ?? ????, 0.1N ???????? 2.0mL? ?? ?, ?? ??? ????? ??.

?????② ?? ?? ????, ? ?? 0.1N ?? 0.5mL? ?? ?, ???? ??.

??(2) ????? : ???? (1)? ????? ?? ??? ???? ??? ? 0.1N ????????? ?? ??? ? ??? ??? ?, ? ???? 1.5mL ????? ??.

??(3) ??? : ? ?? 0.3g? ? 20mL? ?? ?? ?? 0.2g ? ?? 1mL? ?? ?? ?????? ?? ??????? ?? ??? ?, ? ?? 0.001N ?? 1mL? ???? ? ????? ??.

??(4) ? :「???????」? ???? (2)? ?? ????(2.0ppm ??).

????

? (1) ? ??? ??? ???, ????? ?? ?? ???.

??(2) ? ?? 1g? ?????? ?? ?? 15mL? ??? ????? ?? ????? 1?? ??? ?? ???? ?? ?? ?? ? ? ??? ???? ??.

??(3) ? ??? ???(1 → 25)? ????? ? ????? ??? ????.

???

? ? ?? 0.08g? ??? ?? ????·??????(1 : 4) 25mL? ??? ?? ?? 0.1N ???????? ????(??? : ????????·????? 1mL). ???? ?? ???? ??? ???. ?? ?? ???? ???? ??.

??

Sodium fluoride, NaF, is a binary salt that is a clear, lustrous crystal or white powder. The insecticide grade is frequently dyed blue. It is soluble in water and has a specific gravity of 2.558, which is heavier than water. Sodium fluoride is highly toxic by ingestion and inhalation, and is also strongly irritating to tissue. The TLV is 2.5 mg/m3 of air. The four-digit UN identification number is 1690. The primary uses are fluoridation of municipal water at 1 ppm, as an insecticide, rodenticide, and fungicide, and in toothpastes and disinfectants.

??? ??

Sodium fluoride is a white powder or colorless crystals. Often used in a solution. Odorless. Pesticide grade is often dyed blue.

??? ??

Colorless cubic or tetragonal crystals; density 2.78 g/cm³; melts at 993°C; vaporizes at 1,695°C; moderately soluble in water 4.22 g/100mL at 18°C; soluble in hydrofluoric acid; insoluble in ethanol.

?? ??

Sodium fluoride is prepared by adding sodium hydroxide or sodium carbonate to a 40% solution of hydrofluoric acid. In excess hydrofluoric acid, sodium bifluoride, NaHF2 , is formed. NaF also is made by fusion of cryolite with caustic soda. Technical grade products are usually sold at 90 to 95% purity.

??

ChEBI: Sodium fluoride is a metal fluoride salt with a Na(+) counterion. It has a role as a mutagen.

?? ??

Long Yang and colleagues report a highly effective mechanochemical process to recover fluorine from PFAS as NaF,  consists of ball milling PFAS with commercially available sodium silicate^[1].

?? ??

Sodium fluoride is a colorless crystalline solid or white powder, or the solid dissolved in a liquid. Sodium fluoride is formed by the reaction of sodium carbonate and hydrofluoric acid. Sodium fluoride is soluble in water. Sodium fluoride is noncombustible. Sodium fluoride is corrosive to aluminum. Sodium fluoride is used as an insecticide. Sodium fluoride is also used to fluorinate water supplies, as a wood preservative, in cleaning compounds, manufacture of glass, and for many other uses.

???

Toxic by ingestion and inhalation, strong irritant to tissue.

????

Ingestion may cause vomiting, abdominal pain, diarrhea, convulsions, collapse, thirst, disturbed color vision, acute toxic nephritis.

????

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.

??? ? ???

Fluorides are not combustible.

?? ??

Sodium fluoride is a white to yellowish powder, poorly soluble in water. The NaF solubility in water is 3.85% at 15 °C and 4.21% at 25 °C. Commercially, NaF is obtained by reacting hydrofluoric acid with sodium hydroxide. This reaction is a by-product during the production of superphosphates from fluoro-apatite. Sodium fluoride is an important depressant used exclusively during beneficiation of non-sulfide minerals, as well as the rare-earth minerals as a depressant alone or in combination with other depressants. It is used together with starch as co-depressant for rutile and ilmenite during zirconium– titanium separation or during reverse silicate flotation from rutile and ilmenite with cationic collectors. Although it is believed that Na₂F is a silicate depressant, studies have shown that it does not depress silicate minerals. In fact, it improves depression of oxides and silicates when used with other depressants.

Clinical Use

Sodium fluoride (NaF) promotes the proliferation and activity of osteoblasts and is classified as a nonhormonal bone-forming agent. Because treatment with NaF induces bone formation, it is essential that this therapy be coupled with oral calcium supplementation (1,000 mg/day). Additionally, NaF exhibits moderate antiresorptive activity, because it inhibits osteoclastic activity when it is absorbed into the bone matrix. In the treatment of osteoporosis, the therapeutic window for this agent is fairly narrow: Doses less than 45 mg/day are subtherapeutic, and doses in excess of 75 mg/day impair bone mineralization. In addition, the bone that is formed in the presence of NaF is neither as well mineralized nor as strong as normal bone tissue. In fact, some

Safety Profile

Human poison by ingestion. Experimental poison by ingestion, skin contact, intravenous, intraperitoneal, subcutaneous, and intramuscular routes. Human systemic effects: changes in teeth and supporting structures, cyanosis, diarrhea, EKG changes, fluid intake, headache, hypermotihty, increased immune response, muscle weakness, musculo-skeletal changes, nausea or vomiting, paresthesia, ptosis (drooping of the eyelid from sympathetic innervation), respiratory depression, salivary gland changes, tremors. Experimental teratogenic and reproductive effects. Human mutation data reported. A corrosive irritant to skin, eyes, and mucous membranes. Questionable carcinogen with experimental tumorigenic data. It is very phytotoxic. When heated to decomposition it emits toxic fumes of Fand NazO. Used in chemical cleaning, for fluoridation of drinking water, as a funglcide and insecticide. See also FLUORIDES

??? ??

Widely used in the chemical industry; in water treatment and fluoridation of drinking water; as an insecticide, fungicide, and rodenticide; chemical cleaning; electroplating, glass manufacture; vitreous enamels; preservative for adhesives; toothpastes, disinfectant, dental prophylaxis; also used orally in the treatment of various bone diseases to increase bone density and to relieve bone pain.

?? ??

UN1690 Sodium fluoride, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

Purification Methods

Crystallise NaF from water by partial evaporation in a vacuum desiccator, or dissolve it in water, and precipitate ca half of it by adding EtOH. The precipitate is dried in an air oven at 130o for one day, and then stored in a desiccator over KOH. Its solubility in H2O is 4% at 15o and 4.3% at 25o. [Kwasnik in Handbook of Preparative Inorganic Chemistry (Ed. Brauer) Academic Press Vol I p 235 1963].

? ???

Contact with acids release toxic gas. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.

??? ??

In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.

???? ?? ?? ? ???

???

?? ??

???? ?? ??

???	??	???	??	?? ?	??
Wuhan Qiami Technology Co., Ltd	+8618062705058	qiamichem@163.com	China	140	58
Hebei Fengjia New Material Co., Ltd	+86-0311-87836622 +86-18712993135	sales01@tairunfaz.com	China	8051	58
Yingke New Materials Co., Ltd	+86-0314-6276212 +8618631452027	yin81366303@gmail.com	China	27	58
Fujian Sanming Fengyuan New Material Technology Co., Ltd	+86-18806082718 +86-15080556561	sales2@fengyuangroup.com	China	39	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-86-13131129325 +8613131129325	sales1@chuanghaibio.com	China	5225	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971	deasea125996@gmail.com	China	2472	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21586	55
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418679 +8618949832763	info@tnjchem.com	China	2988	55
Shenzhen Excellent Biotech Co., Ltd.	13480692018	ramyan@ex-biotech.com	CHINA	954	58

???? ?? ??: