ChemicalBook >?? ???? >Lefamulin
Lefamulin
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Lefamulin ??
- ?? ?
- 618.6±55.0 °C(Predicted)
- ??
- 1.19±0.1 g/cm3(Predicted)
- ?? ??
- 2-8°C
- ???
- DMF: 16 mg/mL; DMSO: 12 mg/mL; Ethanol: 3 mg/mL; PBS (pH 7.2): 0.25 mg/mL
- ??? ??
- ??
- ?? ?? (pKa)
- 14.45±0.60(Predicted)
- ??
- White to off-white
- InChIKey
- KPVIXBKIJXZQJX-FCEONZPQSA-N
- SMILES
- C(O[C@@H]1C[C@](C=C)(C)[C@@H](O)[C@H](C)[C@@]23CC[C@@H](C)[C@]1(C)[C@]2([H])C(=O)CC3)(=O)CS[C@@H]1CC[C@@H](N)C[C@H]1O
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- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| WGK ?? | WGK 3 | ||
|---|---|---|---|
| ???? ??? | 11 - Combustible Solids | ||
| Hazard Classifications | STOT SE 2 |
| ????(GHS): |
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| ?? ?: | Warning | ||||||||||||||
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Lefamulin C??? ??, ??, ??
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Lefamulin is an antibiotic medication used in the treatment of adults with community-acquired bacterial pneumonia.Synthesis
synthesis route of Lefamulin
Lefamulin ?? ?? ? ???
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Cyclohexene, 4-isocyanato-, (4R)-
Acetic acid, 2-[[(1R,2R,4R)-2-hydroxy-4-[(2,2,2-trifluoroacetyl)amino]cyclohexyl]thio]-, (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester
1350636-88-2
tert-butyl N-[(1R)-cyclohex-3-en-1-yl]carbamate
tert-butyl N-[(1R,3R,4R)-3-hydroxy-4-sulfanylcyclohexyl]carbamate
TiaMulin Related CoMpound A
{(1R,2R,4R)-4-[(tert-butoxycarbonyl)-amino]-2-hydroxy-cyclohexyl} benzene-carbothioate
(R)-(+)-3-??????????
3-Cyclohexenecarboxylic acid
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Lefamulin ?? ??
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