ChemicalBook >?? ???? >??? ??>???>??? ?????>??? ?? ???>Amiloride hydrochloride dihydrate

Amiloride hydrochloride dihydrate

Amiloride hydrochloride dihydrate ??? ???

?? ??:: 17440-83-4

???:: Amiloride hydrochloride dihydrate

???(??):: AMilorida;AMILORIDE HCL DIHYDRATE;Modamide;Amiloride hydrochlorid;AMiloride hydrocholride;AMILORIDEHYDROCHLORIDE,USP;MK-870 hydrochloride dihydrate;Miloride hydrochloride dihydrate;AMILORIDE HYDROCHLORIDE (500 MG);Amiloride HCl dihydrate (MK 870)

CBNumber:: CB9501409

???:: C6H8ClN7O.HCl.2H2O

??? ??:: 302.12

MOL ??:: 17440-83-4.mol

MSDS ??:: SDS

?? ?? 189

Amiloride hydrochloride dihydrate ??

???: >240℃

RTECS ??: UQ2275500

?? ??: Store at -20°C

???: ?? ?? ???? ?? ?????.

?? ?? (pKa): 8.7(at 25℃)

??? ??: Solid

??: Off-white to yellow

???: 50mg/ml? ?? ???

?? ??: ??

InChI: InChI=1S/C6H8ClN7O.ClH.2H2O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11;;;/h(H4,8,9,13)(H4,10,11,14,15);1H;2*1H2

InChIKey: LTKVFMLMEYCWMK-UHFFFAOYSA-N

SMILES: C1(C(NC(N)=N)=O)=NC(Cl)=C(N)N=C1N.[H]Cl.[H]O[H].[H]O[H]

?? ? ?? ??
?? ? ???? ?? (GHS)

WGK ??	3
?? ??	6.1
HS ??	2933995300
???? ???	11 - Combustible Solids

????(GHS):

?? ?:

Danger

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	?? ??	P- ??
H301	??? ???	?? ?? ?? - ??	?? 3	??		P264, P270, P301+P310, P321, P330,P405, P501

??????:

P264	?? ??? ?? ??? ????.
P264	?? ??? ?? ??? ????.
P270	? ??? ??? ??? ???, ???? ???? ???.
P321	(…) ??? ???.
P405	???? ?????.

Amiloride hydrochloride dihydrate C??? ??, ??, ??

??? ??

Pale yellow or greenish-yellow powder.

??

Amiloride hydrochloride dihydrate is used as a calcium channel and sodium channel protein inhibitor. It reduces electrical potential across tubular epithelium, inhibits angiogenesis and inhibits capillary morphogenesis completely and reversibly at approximately 130 M. Amiloride HCl is an inhibitor of Sodium/Potassium-ATPase Protein. Defines the I2A-amiloride sensitive and I2B-amiloride insensitive imidazoline binding Blocks TRPP3, acid sensing- (ASIC) and mechanogated membrane-ion channels, as well as the Na+/H+ exchanger. Also inhibits urokinase-type plasminogen activator (uPA); has no effect on tissue-type plasminogen activator.

??

ChEBI: A hydrate that is the dihydrate of amiloride hydrochloride.

Amiloride hydrochloride dihydrate ?? ?? ? ???

???

?? ??

Amiloride hydrochloride dihydrate ?? ??

???( 189)?? ??

???	??	???	??	?? ?	??
Hebei Chuanghai Biotechnology Co., Ltd	+86-15350571055	Sibel@chuanghaibio.com	China	8737	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21531	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29766	58
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49906	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +86-189 4982 3763	sales@tnjchem.com	China	34526	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6290	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1059@dideu.com	China	29096	58
BOC Sciences	16314854226; +8616314854226	inquiry@bocsci.com	United States	19852	58
Guangzhou TongYi biochemistry technology Co.,LTD		tongyibiochem@163.com	China	2988	58

Amiloride hydrochloride dihydrate ?? ??:

N,N-????????? ????? ????? ?????? P-????????? ????? D-????? Topotecan hydrochloride alminoprofen Chlorantraniliprole 4-AMINOAZOBENZENE HYDROCHLORIDE CHARYBDOTOXIN Nicardipine hydrochloride DOTARIZINE AMILORIDE 5-(N,N-HEXAMETHYLENE)-AMILORIDE FOROXYMITHINE Amiloride hydrochloride dihydrate

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