Amiloride hydrochloride dihydrate
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- CAS-Nr.
- 17440-83-4
- Englisch Name:
- Amiloride hydrochloride dihydrate
- Synonyma:
- AMilorida;AMILORIDE HCL DIHYDRATE;Modamide;Amiloride hydrochlorid;AMiloride hydrocholride;AMILORIDEHYDROCHLORIDE,USP;MK-870 hydrochloride dihydrate;Miloride hydrochloride dihydrate;AMILORIDE HYDROCHLORIDE (500 MG);Amiloride HCl dihydrate (MK 870)
- CBNumber:
- CB9501409
- Summenformel:
- C6H8ClN7O.HCl.2H2O
- Molgewicht:
- 302.12
- MOL-Datei:
- 17440-83-4.mol
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Amiloride hydrochloride dihydrate Eigenschaften
- Schmelzpunkt:
- >240℃
- RTECS-Nr.
- UQ2275500
- storage temp.
- Store at -20°C
- L?slichkeit
- Slightly soluble in water and in anhydrous ethanol.
- pka
- 8.7(at 25℃)
- Aggregatzustand
- Solid
- Farbe
- Off-white to yellow
- Wasserl?slichkeit
- Soluble in water at 50mg/ml
- Major Application
- pharmaceutical
- InChI
- InChI=1S/C6H8ClN7O.ClH.2H2O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11;;;/h(H4,8,9,13)(H4,10,11,14,15);1H;2*1H2
- InChIKey
- LTKVFMLMEYCWMK-UHFFFAOYSA-N
- SMILES
- C1(C(NC(N)=N)=O)=NC(Cl)=C(N)N=C1N.[H]Cl.[H]O[H].[H]O[H]
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| WGK Germany |
3 |
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| HazardClass |
6.1 |
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| HS Code |
2933995300 |
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| Speicherklasse |
11 - Combustible Solids |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H301 |
Giftig bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 3 |
Achtung |
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P264, P270, P301+P310, P321, P330,P405, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P321 |
Besondere Behandlung |
| P405 |
Unter Verschluss aufbewahren. |
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Amiloride hydrochloride dihydrate Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Pale yellow or greenish-yellow powder.
Verwenden
Amiloride hydrochloride dihydrate is used as a calcium channel and sodium channel protein inhibitor. It reduces electrical potential across tubular epithelium, inhibits angiogenesis and inhibits capillary morphogenesis completely and reversibly at approximately 130 M. Amiloride HCl is an inhibitor of Sodium/Potassium-ATPase Protein. Defines the I2A-amiloride sensitive and I2B-amiloride insensitive imidazoline binding Blocks TRPP3, acid sensing- (ASIC) and mechanogated membrane-ion channels, as well as the Na+/H+ exchanger. Also inhibits urokinase-type plasminogen activator (uPA); has no effect on tissue-type plasminogen activator.
Definition
ChEBI: A hydrate that is the dihydrate of amiloride hydrochloride.
Amiloride hydrochloride dihydrate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Amiloride hydrochloride dihydrate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 189)Lieferanten
17440-83-4()Verwandte Suche:
- Modamide
- AMILORIDE HYDROCHLORIDE 2-HYDRATE
- Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-, monohydrochloride, dihydrate
- AMILORIDE HYDROCHLORIDE (500 MG)
- AMILORIDEHYDROCHLORIDE,USP
- 3,5-Diamino-N-(aminoiminomethyl)-6-chloropyrazinecarboxamide hydrochloride dihydrate
- Amiloride hydrochloride dihydrate
- Miloride hydrochloride dihydrate
- AMiloride hydrocholride
- 3,5-diamino-N-(aminoiminomethyl)-6-chloro-2-pyrazinecarboxamide, hydrochloride, hydrate (1:1:2)
- Amiloride Hydrochloride(HCl 2H20)
- MK-870 hydrochloride dihydrate
- Amiloride ,Amiloride Hydrochloride
- Amiloride hydrochlorid
- Amiloride hydrochloride dihydrate USP/EP/BP
- 3,5-Diamino-N-(aminomethyl)-6-chloropyrazine carboxamide hydrochloride dihydrate
- Amiloride HCl dihydrate (MK 870)
- Amiloride for peak identification (Y0001902)
- TIANFU-CHEM 17440-83-4 Amiloride hydrochloride dihydrate
- Amiloride Hydrochloride (1019701)
- 2-Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-, hydrochloride, hydrate (1:1:2)
- AMILORIDE HYDROCHLORIDE IP/BP/USP
- Amiloride Hydrochloride 1.0 mg/ml in Methanol (as free base)
- N-Amidino-3,5-diamino-6-chloropyrazinamide hydrochloride dihydrate
- AMILORIDE HCL DIHYDRATE
- AMilorida
- 17440-83-4
- C6H8ClN7OHCl2H2O
- C6H13Cl2N7O3
- C6H9ClN7O
- MK-870
