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DR2313 | PARP inhibitor

DR2313 | PARP inhibitor ??? ???

?? ??:: 284028-90-6

???:: DR2313 | PARP inhibitor

???(??):: DR 2313;IR 2313;SC-202756;DR2313 >=98% (HPLC);PARP Inhibitor XI, DR2313;4H-Thiopyrano[4,3-d]pyriMidin-4-one,3,5,7,8-tetrahydro-2;DR2313 (PARP Inhibitor XI), brain-penetrant PARP inhibitor;7,8-Dihydro-2-methyl-1H-thiopyrano[4,3-d]pyrimidin-4(5H)-one;3,5,7,8-Tetrahydro-2-methyl-4H-thiopyrano[4,3-d]pyrimidin-4-one;1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE

CBNumber:: CB9837735

???:: C8H10N2OS

??? ??:: 182.24

MOL ??:: 284028-90-6.mol

MSDS ??:: SDS

?? ?? 131

DR2313 | PARP inhibitor ??

?? ?: 349.3±52.0 °C(Predicted)

??: 1.46±0.1 g/cm3(Predicted)

?? ??: Sealed in dry,2-8°C

???: H2O: >2mg/mL(??)

?? ?? (pKa): 1.54±0.20(Predicted)

??? ??: ??

??: ???? ????

???: H2O: >2mg/mL (warmed)

InChI: 1S/C8H10N2OS/c1-5-9-7-2-3-12-4-6(7)8(11)10-5/h2-4H2,1H3,(H,9,10,11)

InChIKey: HRYKZAKEAVZGJD-UHFFFAOYSA-N

SMILES: CC1=NC(=O)C2=C(CCSC2)N1

?? ? ?? ??
?? ? ???? ?? (GHS)

WGK ??	3
???? ???	11 - Combustible Solids

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	P- ??
H302	??? ???	?? ?? ?? - ??	?? 4	??	P264, P270, P301+P312, P330, P501
H315	??? ??? ???	????? ?? ?????	?? 2	??	P264, P280, P302+P352, P321,P332+P313, P362
H319	?? ?? ??? ???	?? ? ?? ?? ??? ??	?? 2A	??	P264, P280, P305+P351+P338,P337+P313P
H335	?? ???? ??? ? ??	?? ???? ?? - 1? ??;???? ??	?? 3	??

??????:

P261	??·?·??·???·??·...·????? ??? ????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

NFPA 704

	0
2		0

DR2313 | PARP inhibitor C??? ??, ??, ??

???? ??

Potent, competitive inhibitor of poly(ADP-ribose) polymerase (PARP) (IC 50 values are 0.20 and 0.24 μ M for PARP-1 and PARP-2 respectively). Neuroprotective; reduces neuronal cell death in models of cerebral ischemia in vivo and in vitro . Brain penetrant.

DR2313 | PARP inhibitor ?? ?? ? ???

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DR2313 | PARP inhibitor ?? ??

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Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63645	58
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DAYANG CHEM (HANGZHOU) CO.,LTD	+86-88938639 +86-17705817739	info@dycnchem.com	China	53799	58

DR2313 | PARP inhibitor ?? ??:

4-AMINO-1,8-NAPHTHALIMIDE 3-Aminobenzamide NU1025 4-Hydroxyquinazoline Rucaparib DPQ ABT-888 PJ 34 hydrochloride PF-01367338 Benzamide Minocycline hydrochloride 1,5-ISOQUINOLINEDIOL 1(2H)-Isoquinolinone, 5-aMino-, Monohydrochloride 5-Benzoyloxy-1(2H)-isoquinolinone 3-(4-CHLORO-PHENYL)-QUINOXALINE-5-CARBOXYLIC ACID AMIDE TIQ-A DR2313 | PARP inhibitor

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