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ChemicalBook >> CAS DataBase List >> (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester

(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester

(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester price.
  • $23 - $5600
  • Product name: (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester
  • CAS: 149809-43-8
  • MF: C21H21F2N3O4S
  • MW: 449.47
  • EINECS:1308068-626-2
  • MDL Number:MFCD13195567
  • Synonyms:Posaconazole InterMediate;Posaconazole Main Ring;(3S,5R)-5-(2,4-Difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-ylmethyl p-Toluenesulfonate;Posaconazole int1;Posaconazole Intermediate1;Posa-12 ((3S,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate;((3S,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)-tetrahydrofuran-3-yl)methyl;(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester
49 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • Acrotein
  • AK Scientific
  • Alichem
  • American Custom Chemicals Corporation
  • Ark Pharm
  • Chemenu
  • Chem-Impex
  • Crysdot
  • Labseeker
  • Matrix Scientific
  • Synthonix
  • TCI Chemical
  • TRC
  • Usbiological
Package
  • 5MG
  • 10MG
  • 100mg
  • 200MG
  • 250mg
  • 500mg
  • 1.00g
  • 1g
  • 5g
  • 5.00g
  • 25g
  • 25.00g
  • 1000g
  • Manufactureraablocks
  • Product numberAA001LYD
  • Product description(3S,5R)-5-(2,4-Difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-ylmethyl p-Toluenesulfonate 98%
  • Packaging1g
  • Price$23
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001LYD
  • Product description(3S,5R)-5-(2,4-Difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-ylmethyl p-Toluenesulfonate 98%
  • Packaging5g
  • Price$76
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001LYD
  • Product description(3S,5R)-5-(2,4-Difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-ylmethyl p-Toluenesulfonate 95%
  • Packaging25g
  • Price$360
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberT99103
  • Product description(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester 95%
  • Packaging25G
  • Price$285
  • Updated2026-05-27
  • Buy
  • ManufacturerAcrotein
  • Product numberdm-2613
  • Product description(3S,5R)-5-(1,2,4-Triazol-1-yl-methyl)-5-(2,4-difluorophenyl)-3-(tosyloxymethyl)tetrahydrofuran 98%
  • Packaging25g
  • Price$313.6
  • Updated2026-05-25
  • Buy
  • ManufacturerAcrotein
  • Product numberdm-2613
  • Product description(3S,5R)-5-(1,2,4-Triazol-1-yl-methyl)-5-(2,4-difluorophenyl)-3-(tosyloxymethyl)tetrahydrofuran 98%
  • Packaging5g
  • Price$93.1
  • Updated2026-05-25
  • Buy
  • ManufacturerAcrotein
  • Product numberDM-2613
  • Product descriptionPosaconazoleIntermidate1 98%
  • Packaging1g
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerAcrotein
  • Product numberdm-2613
  • Product description(3S,5R)-5-(1,2,4-Triazol-1-yl-methyl)-5-(2,4-difluorophenyl)-3-(tosyloxymethyl)tetrahydrofuran 98%
  • Packaging1g
  • Price$28.7
  • Updated2026-05-25
  • Buy
  • ManufacturerAK Scientific
  • Product numberZ3480
  • Product description(5R-cis)-Toluene-4-sulfonicacid5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethylester
  • Packaging100mg
  • Price$56
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberZ3480
  • Product description(5R-cis)-Toluene-4-sulfonicacid5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethylester
  • Packaging250mg
  • Price$112
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ96388
  • Product description(5R-cis)-Toluene-4-sulfonicacid5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethylester
  • Packaging1g
  • Price$217
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number149809438
  • Product description((3S,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl4-methylbenzenesulfonate
  • Packaging1g
  • Price$178.2
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number149809438
  • Product description((3S,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl4-methylbenzenesulfonate
  • Packaging5g
  • Price$530
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0029265
  • Product description(5R-CIS)-TOLUENE-4-SULFONIC ACID 5-(2,4-DIFLUOROPHENYL)-5-(1H-1,2,4-TRIAZOL-1-YL)METHYLTETRAHYDROFURAN-3-YLMETHYL ESTER 95.00%
  • Packaging10MG
  • Price$691.27
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0029265
  • Product description(5R-CIS)-TOLUENE-4-SULFONIC ACID 5-(2,4-DIFLUOROPHENYL)-5-(1H-1,2,4-TRIAZOL-1-YL)METHYLTETRAHYDROFURAN-3-YLMETHYL ESTER 95.00%
  • Packaging100MG
  • Price$1709.98
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPN0002083
  • Product description(5R-CIS)-TOLUENE-4-SULFONIC ACID-5-(2,4-DIFLUOROPHENYL)-5-[1,2,4]TRIAZOL-1-YLMETHYLTETRAHYDROFURAN-3-YL-METHYL ESTER 95.00%
  • Packaging5MG
  • Price$497.48
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA001LYD (3S,5R)-5-(2,4-Difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-ylmethyl p-Toluenesulfonate 98% 1g $23 2026-05-28 Buy
aablocks AA001LYD (3S,5R)-5-(2,4-Difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-ylmethyl p-Toluenesulfonate 98% 5g $76 2026-05-28 Buy
aablocks AA001LYD (3S,5R)-5-(2,4-Difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-ylmethyl p-Toluenesulfonate 95% 25g $360 2026-05-28 Buy
ACHEMBLOCK T99103 (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester 95% 25G $285 2026-05-27 Buy
Acrotein dm-2613 (3S,5R)-5-(1,2,4-Triazol-1-yl-methyl)-5-(2,4-difluorophenyl)-3-(tosyloxymethyl)tetrahydrofuran 98% 25g $313.6 2026-05-25 Buy
Acrotein dm-2613 (3S,5R)-5-(1,2,4-Triazol-1-yl-methyl)-5-(2,4-difluorophenyl)-3-(tosyloxymethyl)tetrahydrofuran 98% 5g $93.1 2026-05-25 Buy
Acrotein DM-2613 PosaconazoleIntermidate1 98% 1g $110 2021-12-16 Buy
Acrotein dm-2613 (3S,5R)-5-(1,2,4-Triazol-1-yl-methyl)-5-(2,4-difluorophenyl)-3-(tosyloxymethyl)tetrahydrofuran 98% 1g $28.7 2026-05-25 Buy
AK Scientific Z3480 (5R-cis)-Toluene-4-sulfonicacid5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethylester 100mg $56 2021-12-16 Buy
AK Scientific Z3480 (5R-cis)-Toluene-4-sulfonicacid5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethylester 250mg $112 2021-12-16 Buy
AK Scientific J96388 (5R-cis)-Toluene-4-sulfonicacid5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethylester 1g $217 2021-12-16 Buy
Alichem 149809438 ((3S,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl4-methylbenzenesulfonate 1g $178.2 2021-12-16 Buy
Alichem 149809438 ((3S,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl4-methylbenzenesulfonate 5g $530 2021-12-16 Buy
American Custom Chemicals Corporation HCH0029265 (5R-CIS)-TOLUENE-4-SULFONIC ACID 5-(2,4-DIFLUOROPHENYL)-5-(1H-1,2,4-TRIAZOL-1-YL)METHYLTETRAHYDROFURAN-3-YLMETHYL ESTER 95.00% 10MG $691.27 2021-12-16 Buy
American Custom Chemicals Corporation HCH0029265 (5R-CIS)-TOLUENE-4-SULFONIC ACID 5-(2,4-DIFLUOROPHENYL)-5-(1H-1,2,4-TRIAZOL-1-YL)METHYLTETRAHYDROFURAN-3-YLMETHYL ESTER 95.00% 100MG $1709.98 2021-12-16 Buy
American Custom Chemicals Corporation APN0002083 (5R-CIS)-TOLUENE-4-SULFONIC ACID-5-(2,4-DIFLUOROPHENYL)-5-[1,2,4]TRIAZOL-1-YLMETHYLTETRAHYDROFURAN-3-YL-METHYL ESTER 95.00% 5MG $497.48 2021-12-16 Buy

Properties

Melting point :100-102°C
Boiling point :608.1±65.0 °C(Predicted)
Density :1.40
storage temp. :-20°C Freezer, Under Inert Atmosphere
solubility :slightly sol. in Chloroform
form :powder to crystal
pka :2.75±0.10(Predicted)
color :White to Orange to Green
InChI :InChI=1S/C21H21F2N3O4S/c1-15-2-5-18(6-3-15)31(27,28)30-11-16-9-21(29-10-16,12-26-14-24-13-25-26)19-7-4-17(22)8-20(19)23/h2-8,13-14,16H,9-12H2,1H3/t16-,21-/m0/s1
InChIKey :DFWVLCJRFGIRAK-HRAATJIYSA-N
SMILES :C1[C@](CN2N=CN=C2)(C2C(F)=CC(F)=CC=2)OC[C@H]1COS(=O)(=O)C1C=CC(C)=CC=1
CAS DataBase Reference :149809-43-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): Skull and Crossbones (GHS06)Health Hazard (GHS08)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
H311 Toxic in contact with skin Acute toxicity,dermal Category 3 Danger P280, P302+P352, P312, P322, P361,P363, P405, P501
H331 Toxic if inhaled Acute toxicity,inhalation Category 3 Danger P261, P271, P304+P340, P311, P321,P403+P233, P405, P501
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P310 Immediately call a POISON CENTER or doctor/physician.
P330 Rinse mouth.
P361 Remove/Take off immediately all contaminated clothing.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Posaconazole intermediate. Antifungal agent.

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