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ChemicalBook >> CAS DataBase List >> tert-Butyldimethylsilyl chloride

tert-Butyldimethylsilyl chloride

tert-Butyldimethylsilyl chloride price.
  • $8 - $2995
  • Product name: tert-Butyldimethylsilyl chloride
  • CAS: 18162-48-6
  • MF: C6H15ClSi
  • MW: 150.72
  • EINECS:242-042-4
  • MDL Number:MFCD00000501
  • Synonyms:SILANE TBM2;T-BUTYLDIMENHYLSILYL CHLORIDE;t-butyl dimethyl chlorsilane;TBUME2SI-CL;TERT-BUTYLDIMETHYLSILYL CHLORIDE;T-butyldimethylsilyl chloride*crystalline;tert-Butyl Dimethylchlorosilane (TBDMSCl);chloro-dimethyl-tert-butyl-silane
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  • Manufactureraablocks
  • Product numberAA0035KP
  • Product descriptionTert-Butyldimethylchlorosilane 99%
  • Packaging5g
  • Price$8
  • Updated2026-05-28
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  • Product descriptionTert-Butyldimethylchlorosilane ≥97%
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  • Updated2026-05-28
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  • Product descriptionTert-Butyldimethylchlorosilane 99%
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  • Manufactureraablocks
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  • Product descriptionTert-Butyldimethylchlorosilane 99%
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  • Updated2026-05-28
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  • Product numberAA0035KP
  • Product descriptionTert-Butyldimethylchlorosilane 99%
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  • Product numberAA0035KP
  • Product descriptionTert-Butyldimethylchlorosilane 99%
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  • Price$80
  • Updated2026-05-28
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  • ManufacturerAK Scientific
  • Product numberJ54985
  • Product descriptiontert-Butyldimethylsilyl chloride (TBDMSCl) 98%
  • Packaging500g
  • Price$104
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberD055
  • Product descriptiontert-Butyldimethylsilylchloride(TBDMSCl)
  • Packaging4x25g
  • Price$109
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ54985
  • Product descriptiontert-Butyldimethylsilyl chloride (TBDMSCl) 98%
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  • Price$60
  • Updated2026-06-04
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  • ManufacturerAK Scientific
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  • Product descriptiontert-Butyldimethylsilyl chloride (TBDMSCl) 99%(GC)
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  • Price$75
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  • ManufacturerAK Scientific
  • Product numberD055
  • Product descriptiontert-Butyldimethylsilyl chloride (TBDMSCl) 99%(GC)
  • Packaging500g
  • Price$130
  • Updated2026-06-04
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  • ManufacturerAK Scientific
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  • Product descriptiontert-Butyldimethylsilyl chloride (TBDMSCl) 98%
  • Packaging1kg
  • Price$169
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ54985
  • Product descriptiontert-Butyldimethylsilylchloride(TBDMSCl)
  • Packaging500g
  • Price$180
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ54985
  • Product descriptiontert-Butyldimethylsilyl chloride (TBDMSCl) 98%
  • Packaging100g
  • Price$42
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberD055
  • Product descriptiontert-Butyldimethylsilyl chloride (TBDMSCl) 99%(GC)
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  • Price$52
  • Updated2026-06-04
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  • ManufacturerAK Scientific
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  • Product descriptiontert-Butyldimethylsilyl chloride (TBDMSCl) 98%
  • Packaging25g
  • Price$22
  • Updated2026-06-04
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Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0035KP Tert-Butyldimethylchlorosilane 99% 5g $8 2026-05-28 Buy
aablocks AA0035KP Tert-Butyldimethylchlorosilane ≥97% 25g $12 2026-05-28 Buy
aablocks AA0035KP Tert-Butyldimethylchlorosilane 99% 100g $23 2026-05-28 Buy
aablocks AA0035KP Tert-Butyldimethylchlorosilane 99% 250g $40 2026-05-28 Buy
aablocks AA0035KP Tert-Butyldimethylchlorosilane 99% 500g $60 2026-05-28 Buy
aablocks AA0035KP Tert-Butyldimethylchlorosilane 99% 1kg $80 2026-05-28 Buy
AK Scientific J54985 tert-Butyldimethylsilyl chloride (TBDMSCl) 98% 500g $104 2026-06-04 Buy
AK Scientific D055 tert-Butyldimethylsilylchloride(TBDMSCl) 4x25g $109 2021-12-16 Buy
AK Scientific J54985 tert-Butyldimethylsilyl chloride (TBDMSCl) 98% 250g $60 2026-06-04 Buy
AK Scientific D055 tert-Butyldimethylsilyl chloride (TBDMSCl) 99%(GC) 250g $75 2026-06-04 Buy
AK Scientific D055 tert-Butyldimethylsilyl chloride (TBDMSCl) 99%(GC) 500g $130 2026-06-04 Buy
AK Scientific J54985 tert-Butyldimethylsilyl chloride (TBDMSCl) 98% 1kg $169 2026-06-04 Buy
AK Scientific J54985 tert-Butyldimethylsilylchloride(TBDMSCl) 500g $180 2021-12-16 Buy
AK Scientific J54985 tert-Butyldimethylsilyl chloride (TBDMSCl) 98% 100g $42 2026-06-04 Buy
AK Scientific D055 tert-Butyldimethylsilyl chloride (TBDMSCl) 99%(GC) 100g $52 2026-06-04 Buy
AK Scientific J54985 tert-Butyldimethylsilyl chloride (TBDMSCl) 98% 25g $22 2026-06-04 Buy

Properties

Melting point :86-89 °C (lit.)
Boiling point :125 °C (lit.)
Density :0.87 g/mL at 20 °C(lit.)
vapor pressure :60-710Pa at 25℃
refractive index :n20/D 1.46
Flash point :73 °F
storage temp. :Store below +30°C.
solubility :very sol nearly all common organic solvents such as THF, methylene chloride, and DMF.
form :white solid
Specific Gravity :1.225
color :white
Water Solubility :Soluble in chloroform and ethyl acetate. Insoluble in water.
Sensitive :Moisture Sensitive
Hydrolytic Sensitivity :7: reacts slowly with moisture/water
BRN :505999
Exposure limits :ACGIH: TWA 20 ppm
OSHA: Ceiling 300 ppm; TWA 200 ppm
NIOSH: IDLH 500 ppm; TWA 100 ppm(375 mg/m3); STEL 150 ppm(560 mg/m3) InChI :1S/C6H15ClSi/c1-6(2,3)8(4,5)7/h1-5H3
InChIKey :BCNZYOJHNLTNEZ-UHFFFAOYSA-N
SMILES :CC(C)(C)[Si](C)(C)Cl
LogP :2.5 at 20℃
CAS DataBase Reference :18162-48-6(CAS DataBase Reference)
NIST Chemistry Reference :Silane, chloro(1,1-dimethylethyl)dimethyl-(18162-48-6)
EPA Substance Registry System :Silane, chloro(1,1-dimethylethyl)dimethyl- (18162-48-6)

Safety Information

Symbol(GHS): Flame (GHS02)Corrosion (GHS05)Exclamation Mark (GHS07)Health Hazard (GHS08)Environment (GHS09)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H304 May be fatal if swallowed and enters airways Aspiration hazard Category 1 Danger
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

Description

tert-Butyldimethylchlorosilane is used to protect hydroxyl group in organic synthesis. It finds application in the synthesis of prostaglandin. It is also used as an auxiliary material for hypolipaemics such as lovastatin and simvastatin. It plays an important role in the preparation of isoxazolines N-oxides from alpha-bromonitroalkanes. It acts as a versatile protecting reagent for amines, amides and alcohols.

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