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ChemicalBook >> CAS DataBase List >> 1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone

1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone

$30 - $2839
Product name: 1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone
CAS: 314245-33-5
MF: C18H21FN2O
MW: 300.37
EINECS:232-983-9
MDL Number:MFCD01917473
Synonyms:1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone;1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2-(1-PYRROLIDINYL)ETHANONE;IU1;1-(1-(4-fluorophenyl)-2,5-diMethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethanone;Ethanone, 1-[1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)-;IU-1 (USP14 inhibitor IU1);IU1; IU-1; IU 1;CS-1901;1-[1-(4-Fluorophenyl)-2,5-dimethylpyrrol-3-yl]-2-(pyrrolidin-1-yl)ethanone

Price77 Properties Safety Information Description

77 prices

Selected condition：

Brand

aablocks
ACHEMBLOCK
AK Scientific
American Custom Chemicals Corporation
ApexBio Technology
Arctom
AvaChem
Biorbyt Ltd
Biosynth
Cayman Chemical
Chemenu
ChemScene
Crysdot
DC Chemicals
Medical Isotopes, Inc.
Sigma-Aldrich
TRC
Usbiological

Package

10mM*1mLinDMSO(Solution)
10mM(1mLinDMSO)
1mg
10mM*1mLinDMSO(Solid+Solvent)
5mg
10mg
25mg
50mg
100mg
10mM(in 1mL DMSO)
200mg
250mg
1G
5G
10mM(in1mLDMSO)
2.5G

Manufactureraablocks
Product numberAA00C0TR
Product description1-(1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethanone ≥98%
Packaging5mg
Price$42
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00C0TR
Product description1-(1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethanone
Packaging25mg
Price$137
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00C0TR
Product description1-(1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethanone
Packaging10mg
Price$81
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00C0TR
Product description1-(1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethanone
Packaging50mg
Price$222
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00C0TR
Product description1-(1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethanone
Packaging100mg
Price$379
Updated2026-05-28
Buy

ManufacturerACHEMBLOCK
Product numberM15308
Product descriptionIU1 98%
Packaging1G
Price$1250
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product numberM15308
Product descriptionIU1 98%
Packaging25MG
Price$130
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberM15308
Product descriptionIU1 98%
Packaging100MG
Price$350
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberM15308
Product descriptionIU1 98%
Packaging5MG
Price$50
Updated2026-05-27
Buy

ManufacturerAK Scientific
Product numberSYN5673
Product descriptionIU1
Packaging10mg
Price$198
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product numberSYN5673
Product descriptionIU1
Packaging100mg
Price$1174
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberINB0001404
Product description1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2-(1-PYRROLIDINYL)ETHANONE 95.00%
Packaging5G
Price$1018
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberINB0001404
Product description1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2-(1-PYRROLIDINYL)ETHANONE 95.00%
Packaging2.5G
Price$818
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberINB0001404
Product description1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2-(1-PYRROLIDINYL)ETHANONE 95.00%
Packaging5MG
Price$401.06
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberINB0001404
Product description1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2-(1-PYRROLIDINYL)ETHANONE 95.00%
Packaging1G
Price$613
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA4002
Product descriptionIU1
Packaging100mg
Price$360
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA00C0TR	1-(1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethanone ≥98%	5mg	$42	2026-05-28	Buy
aablocks	AA00C0TR	1-(1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethanone	25mg	$137	2026-05-28	Buy
aablocks	AA00C0TR	1-(1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethanone	10mg	$81	2026-05-28	Buy
aablocks	AA00C0TR	1-(1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethanone	50mg	$222	2026-05-28	Buy
aablocks	AA00C0TR	1-(1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethanone	100mg	$379	2026-05-28	Buy
ACHEMBLOCK	M15308	IU1 98%	1G	$1250	2026-05-27	Buy
ACHEMBLOCK	M15308	IU1 98%	25MG	$130	2026-05-27	Buy
ACHEMBLOCK	M15308	IU1 98%	100MG	$350	2026-05-27	Buy
ACHEMBLOCK	M15308	IU1 98%	5MG	$50	2026-05-27	Buy
AK Scientific	SYN5673	IU1	10mg	$198	2021-12-16	Buy
AK Scientific	SYN5673	IU1	100mg	$1174	2021-12-16	Buy
American Custom Chemicals Corporation	INB0001404	1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2-(1-PYRROLIDINYL)ETHANONE 95.00%	5G	$1018	2021-12-16	Buy
American Custom Chemicals Corporation	INB0001404	1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2-(1-PYRROLIDINYL)ETHANONE 95.00%	2.5G	$818	2021-12-16	Buy
American Custom Chemicals Corporation	INB0001404	1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2-(1-PYRROLIDINYL)ETHANONE 95.00%	5MG	$401.06	2021-12-16	Buy
American Custom Chemicals Corporation	INB0001404	1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2-(1-PYRROLIDINYL)ETHANONE 95.00%	1G	$613	2021-12-16	Buy
ApexBio Technology	A4002	IU1	100mg	$360	2021-12-16	Buy

Next Last

Properties

Boiling point :437.0±45.0 °C(Predicted)
Density :1.16±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
pka :8.20±0.20(Predicted)
form :powder
color :off-white to light brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChI :1S/C18H21FN2O/c1-13-11-17(18(22)12-20-9-3-4-10-20)14(2)21(13)16-7-5-15(19)6-8-16/h5-8,11H,3-4,9-10,12H2,1-2H3
InChIKey :JUWDSDKJBMFLHE-UHFFFAOYSA-N
SMILES :FC1=CC=C(N2C(C)=CC(C(CN3CCCC3)=O)=C2C)C=C1

Safety Information

Symbol(GHS):

Signal word:

Danger

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes
H318	Causes serious eye damage	Serious eye damage/eye irritation	Category 1	Danger		P280, P305+P351+P338, P310

Precautionary statements:

P280	Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Polybiquitinylation designates proteins for proteasomal degradation. USP14 is one of several deubiquitinating enzymes (DUBs) responsible for shortening proteasome-bound ubiquitin chains, which is known to antagonize the degradation of ubiquitin-protein conjugates. IU1 is a reversible, small molecule inhibitor of deubiquitination by USP14 that demonstrates an IC50 value of 4-5 μM. IU1 selectively stimulates ubiquitin-dependent protein degradation in vitro at 34 μM and in MEF cells at 50 μM. At 75 μM, IU1 reduces accumulation of oxidized proteins in HEK293 cells, alleviating cytotoxicity induced by oxidative stress.

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Suppliers and manufacturers

Dideu Industries Group Limited

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1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone CAS:314245-33-5

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InvivoChem

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Chongqing Chemdad Co., Ltd 3B Pharmachem (Wuhan) International Co.,Ltd. WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. Jinan Trio PharmaTech Co., Ltd.

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1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone

Properties

Safety Information

Description

Related product price

Suppliers and manufacturers