NSC632839hydrochloride
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- $12 - $1100
- Product name: NSC632839hydrochloride
- CAS: 157654-67-6
- MF: C21H21NO.ClH
- MW: 339.864
- EINECS:604-604-1
- MDL Number:MFCD09753281
- Synonyms:Ubiquitin Isopeptidase Inhibitor II, F6;NSC 632839;4-Piperidione,3,5-bis[(4-methylphenyl)methylene] hydrochloride;NSC632839hydrochloride;3,5-Bis[(4-methylphenyl)methylene]-4-piperidonehydrochloride;NSC 632839;NSC-632839;Ubiquitin Isopeptidase Inhibitor II;NSC632839 HCl
70 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
Package
- 10
- 25.00mg
- 10mM*1mLinDMSO(Solution)
- 50.00mg
- 50
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100.00mg
- 100MG
- 250MG
- 1g
- 10mM*1mLinDMSO(Solid+Solvent)
- Manufactureraablocks
- Product numberAA001PJ4
- Product descriptionNSC 632839 98+%
- Packaging1mg
- Price$12
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001PJ4
- Product descriptionNSC 632839 98+%
- Packaging5mg
- Price$24
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001PJ4
- Product descriptionNSC 632839 98+%
- Packaging10mg
- Price$31
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001PJ4
- Product descriptionNSC 632839 98+%
- Packaging25mg
- Price$46
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228132
- Product descriptionNSC632839 97.00%
- Packaging25MG
- Price$160
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228132
- Product descriptionNSC632839 97.00%
- Packaging100MG
- Price$355
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228132
- Product descriptionNSC632839 97.00%
- Packaging250MG
- Price$710
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number2599AH
- Product description4-Piperidione,3,5-bis[(4-methylphenyl)methylene]hydrochloride
- Packaging100mg
- Price$702
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA457204
- Product descriptionNSC632839Hydrochloride 98+%
- Packaging1g
- Price$637
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA457204
- Product descriptionNSC632839Hydrochloride 98+%
- Packaging250mg
- Price$255
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA457204
- Product descriptionNSC632839Hydrochloride 98+%
- Packaging100mg
- Price$127
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA457204
- Product descriptionNSC632839Hydrochloride 98+%
- Packaging50mg
- Price$98
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA457204
- Product descriptionNSC632839Hydrochloride 98+%
- Packaging5mg
- Price$43
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA457204
- Product descriptionNSC632839Hydrochloride 98+%
- Packaging10mg
- Price$58
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA457204
- Product descriptionNSC632839Hydrochloride 98+%
- Packaging25mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001198
- Product descriptionNSC 632839 HYDROCHLORIDE 95.00%
- Packaging5MG
- Price$500.18
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA001PJ4 | NSC 632839 98+% | 1mg | $12 | 2026-05-28 | Buy |
| aablocks | AA001PJ4 | NSC 632839 98+% | 5mg | $24 | 2026-05-28 | Buy |
| aablocks | AA001PJ4 | NSC 632839 98+% | 10mg | $31 | 2026-05-28 | Buy |
| aablocks | AA001PJ4 | NSC 632839 98+% | 25mg | $46 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y228132 | NSC632839 97.00% | 25MG | $160 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y228132 | NSC632839 97.00% | 100MG | $355 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y228132 | NSC632839 97.00% | 250MG | $710 | 2026-05-27 | Buy |
| AK Scientific | 2599AH | 4-Piperidione,3,5-bis[(4-methylphenyl)methylene]hydrochloride | 100mg | $702 | 2021-12-16 | Buy |
| Ambeed | A457204 | NSC632839Hydrochloride 98+% | 1g | $637 | 2021-12-16 | Buy |
| Ambeed | A457204 | NSC632839Hydrochloride 98+% | 250mg | $255 | 2021-12-16 | Buy |
| Ambeed | A457204 | NSC632839Hydrochloride 98+% | 100mg | $127 | 2021-12-16 | Buy |
| Ambeed | A457204 | NSC632839Hydrochloride 98+% | 50mg | $98 | 2021-12-16 | Buy |
| Ambeed | A457204 | NSC632839Hydrochloride 98+% | 5mg | $43 | 2021-12-16 | Buy |
| Ambeed | A457204 | NSC632839Hydrochloride 98+% | 10mg | $58 | 2021-12-16 | Buy |
| Ambeed | A457204 | NSC632839Hydrochloride 98+% | 25mg | $75 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001198 | NSC 632839 HYDROCHLORIDE 95.00% | 5MG | $500.18 | 2021-12-16 | Buy |
Properties
storage temp. :Store at +4°C
solubility :DMSO: ≥2mg/mL (warmed)
form :powder
color :faint yellow to dark yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
InChI :1S/C21H21NO.ClH/c1-15-3-7-17(8-4-15)11-19-13-22-14-20(21(19)23)12-18-9-5-16(2)6-10-18;/h3-12,22H,13-14H2,1-2H3;1H/b19-11+,20-12+;
InChIKey :ZOKZLTXPTLIWOJ-BYCVLTJGSA-N
SMILES :Cl.Cc1ccc(cc1)\C=C2/CNC\C(=C/c3ccc(C)cc3)C2=O
solubility :DMSO: ≥2mg/mL (warmed)
form :powder
color :faint yellow to dark yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
InChI :1S/C21H21NO.ClH/c1-15-3-7-17(8-4-15)11-19-13-22-14-20(21(19)23)12-18-9-5-16(2)6-10-18;/h3-12,22H,13-14H2,1-2H3;1H/b19-11+,20-12+;
InChIKey :ZOKZLTXPTLIWOJ-BYCVLTJGSA-N
SMILES :Cl.Cc1ccc(cc1)\C=C2/CNC\C(=C/c3ccc(C)cc3)C2=O
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Protein ubiquitination is a dynamic process that can be reversed by deubiquitinating enzymes (DUBs) that remove ubiquitin from proteins, sparing them from degradation by the proteasome. The DUBs have been divided into various groups, the largest being the ubiquitin-specific proteases (USPs). NSC 632839 inhibits USP2 and USP7 as well as the ubiquitin-like SUMO peptidase SENP2 with EC50 values of 45, 37, and 9.8 μM, respectively. It is reported to inhibit apoptosis through a Bcl-2-dependent and apoptosome-independent pathway of caspase activation (IC50 = 15.7 μM in cells sensitized by E1A, an adenoviral oncogene).More related product prices
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