CP671305
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- $16 - $2900
- Product name: CP671305
- CAS: 445295-04-5
- MF: C23H19FN2O7
- MW: 454.4
- EINECS:
- MDL Number:MFCD31382154
- Synonyms:CP671305;CP-671305; CP 671305; CP671305; UNII-9LH034R9R9;445295-04-5;UNII-9LH034R9R9;CS-2886;Propanoic acid, 2-[4-[[[[2-(1,3-benzodioxol-5-yloxy)-3-pyridinyl]carbonyl]amino]methyl]-3-fluorophenoxy]-, (2R)-;(R)-2-(4-((2-(benzo[d][1,3]dioxol-5-yloxy)nicotinamido)methyl)-3-fluorophenoxy)propanoic acid;CP 671305,Inhibitor,Phosphodiesterase (PDE),CP671305,CP-671305,inhibit;CP671305, 10 mM in DMSO
33 prices
Selected condition:
Brand
- aablocks
- AK Scientific
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
Package
- 50
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- Manufactureraablocks
- Product numberAA01E7SC
- Product descriptionCP 671305 99%
- Packaging25mg
- Price$53
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E7SC
- Product descriptionCP 671305 99%
- Packaging50mg
- Price$91
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E7SC
- Product descriptionCP 671305 ≥98%
- Packaging5mg
- Price$16
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E7SC
- Product descriptionCP 671305 ≥98%
- Packaging10mg
- Price$28
- Updated2026-05-30
- Buy
- ManufacturerAK Scientific
- Product number4497CR
- Product description(2R)-2-[4-[[[2-(1,3-Benzodioxol-5-yloxy)pyridine-3-carbonyl]amino]methyl]-3-fluorophenoxy]propanoicacid
- Packaging10mg
- Price$299
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberBC161230
- Product descriptionCP 671305
- Packaging5mg
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberBC161230
- Product descriptionCP 671305
- Packaging1mg
- Price$175
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberBC161230
- Product descriptionCP 671305
- Packaging10mg
- Price$185
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberBC161230
- Product descriptionCP 671305
- Packaging10mg
- Price$186.4
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberBC161230
- Product descriptionCP 671305
- Packaging25mg
- Price$1000
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberBC161230
- Product descriptionCP 671305
- Packaging50
- Price$647.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberBC161230
- Product descriptionCP 671305
- Packaging2mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number26743
- Product descriptionCP 671,305
- Packaging1mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number26743
- Product descriptionCP 671,305
- Packaging5mg
- Price$193
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number26743
- Product descriptionCP 671,305 ≥98%
- Packaging5mg
- Price$213
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number26743
- Product descriptionCP 671,305 ≥98%
- Packaging1mg
- Price$49
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01E7SC | CP 671305 99% | 25mg | $53 | 2026-05-30 | Buy |
| aablocks | AA01E7SC | CP 671305 99% | 50mg | $91 | 2026-05-30 | Buy |
| aablocks | AA01E7SC | CP 671305 ≥98% | 5mg | $16 | 2026-05-30 | Buy |
| aablocks | AA01E7SC | CP 671305 ≥98% | 10mg | $28 | 2026-05-30 | Buy |
| AK Scientific | 4497CR | (2R)-2-[4-[[[2-(1,3-Benzodioxol-5-yloxy)pyridine-3-carbonyl]amino]methyl]-3-fluorophenoxy]propanoicacid | 10mg | $299 | 2021-12-16 | Buy |
| Biosynth | BC161230 | CP 671305 | 5mg | $500 | 2021-12-16 | Buy |
| Biosynth | BC161230 | CP 671305 | 1mg | $175 | 2021-12-16 | Buy |
| Biosynth | BC161230 | CP 671305 | 10mg | $185 | 2021-12-16 | Buy |
| Biosynth | BC161230 | CP 671305 | 10mg | $186.4 | 2026-06-04 | Buy |
| Biosynth | BC161230 | CP 671305 | 25mg | $1000 | 2021-12-16 | Buy |
| Biosynth | BC161230 | CP 671305 | 50 | $647.5 | 2021-12-16 | Buy |
| Biosynth | BC161230 | CP 671305 | 2mg | $250 | 2021-12-16 | Buy |
| Cayman Chemical | 26743 | CP 671,305 | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 26743 | CP 671,305 | 5mg | $193 | 2024-03-01 | Buy |
| Cayman Chemical | 26743 | CP 671,305 ≥98% | 5mg | $213 | 2026-04-30 | Buy |
| Cayman Chemical | 26743 | CP 671,305 ≥98% | 1mg | $49 | 2026-04-30 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMF: 50 mg/ml; DMSO: 25 mg/ml; Ethanol: 3 mg/ml; PBS (pH 7.2): 2 mg/ml
form :A crystalline solid
color :White to off-white
solubility :DMF: 50 mg/ml; DMSO: 25 mg/ml; Ethanol: 3 mg/ml; PBS (pH 7.2): 2 mg/ml
form :A crystalline solid
color :White to off-white
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
CP 671,305 is a potent inhibitor of phosphodiesterase 4D (PDE4D; IC50 = 3 nM). It is selective for PDE4D over PDE4A, -B, and -C (IC50s = 310, 287, and 3,858 nM, respectively), as well as over PDE1-3 and 5 (IC50s = >5,000 nM for all). CP 671,305 inhibits release of leukotriene E4 (LTE4; ) from eosinophils (IC50 = 52 nM) and LTB4 from neutrophils (IC50 = 106 nM). In vivo, CP 671,305 inhibits antigen-induced pulmonary eosinophil influx in cynomolgus monkeys in a dose-dependent manner.More related product prices
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