NSC781406
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- $32 - $2400
- Product name: NSC781406
- CAS: 1676893-24-5
- MF: C29H27F2N5O5S2
- MW: 627.68
- EINECS:
- MDL Number:
- Synonyms:NSC781406;NSC781406;NSC-781406;NSC 781406;NSC-781406;NSC 781406;Benzenesulfonamide, 2,4-difluoro-N-[2-methoxy-5-[4-[3-[4-(methylsulfonyl)-1-piperazinyl]-1-propyn-1-yl]-6-quinolinyl]-3-pyridinyl]-;NSC781406,Phosphoinositide 3-kinase,NSC 781406,NSC-781406,PI3K,Mammalian target of Rapamycin,Inhibitor,inhibit,mTOR;2,4-difluoro-N-[2-methoxy-5-[4-[3-[4-(methylsulfonyl)-1-piperazinyl]-1-propyn-1-yl]-6-quinolinyl]-3-pyridinyl]-benzenesulfonamide;NSC781406, 10 mM in DMSO
27 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Cayman Chemical
- ChemScene
- DC Chemicals
Package
- 10mM*1mLinDMSO
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- Manufactureraablocks
- Product numberAA01EO74
- Product descriptionNSC 781406 ≥98%
- Packaging1mg
- Price$36
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EO74
- Product descriptionNSC 781406
- Packaging2mg
- Price$48
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EO74
- Product descriptionNSC 781406
- Packaging5mg
- Price$67
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EO74
- Product descriptionNSC 781406
- Packaging10mg
- Price$96
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EO74
- Product descriptionNSC 781406
- Packaging25mg
- Price$157
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EO74
- Product descriptionNSC 781406
- Packaging50mg
- Price$226
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EO74
- Product descriptionNSC 781406
- Packaging100mg
- Price$336
- Updated2026-05-30
- Buy
- ManufacturerACHEMBLOCK
- Product numberY226771
- Product descriptionNSC781406 97.00%
- Packaging100MG
- Price$470
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY226771
- Product descriptionNSC781406 97.00%
- Packaging25MG
- Price$205
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number5398EJ
- Product description2,4-Difluoro-N-[2-methoxy-5-[4-[3-(4-methylsulfonylpiperazin-1-yl)prop-1-ynyl]quinolin-6-yl]pyridin-3-yl]benzenesulfonamide
- Packaging5mg
- Price$252
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number29226
- Product descriptionNSC 781406
- Packaging10mg
- Price$261
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29226
- Product descriptionNSC 781406 ≥98%
- Packaging10mg
- Price$288
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number29226
- Product descriptionNSC 781406
- Packaging5mg
- Price$139
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29226
- Product descriptionNSC 781406 ≥98%
- Packaging5mg
- Price$153
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number29226
- Product descriptionNSC 781406
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29226
- Product descriptionNSC 781406 ≥98%
- Packaging1mg
- Price$36
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01EO74 | NSC 781406 ≥98% | 1mg | $36 | 2026-05-30 | Buy |
| aablocks | AA01EO74 | NSC 781406 | 2mg | $48 | 2026-05-30 | Buy |
| aablocks | AA01EO74 | NSC 781406 | 5mg | $67 | 2026-05-30 | Buy |
| aablocks | AA01EO74 | NSC 781406 | 10mg | $96 | 2026-05-30 | Buy |
| aablocks | AA01EO74 | NSC 781406 | 25mg | $157 | 2026-05-30 | Buy |
| aablocks | AA01EO74 | NSC 781406 | 50mg | $226 | 2026-05-30 | Buy |
| aablocks | AA01EO74 | NSC 781406 | 100mg | $336 | 2026-05-30 | Buy |
| ACHEMBLOCK | Y226771 | NSC781406 97.00% | 100MG | $470 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y226771 | NSC781406 97.00% | 25MG | $205 | 2026-05-27 | Buy |
| AK Scientific | 5398EJ | 2,4-Difluoro-N-[2-methoxy-5-[4-[3-(4-methylsulfonylpiperazin-1-yl)prop-1-ynyl]quinolin-6-yl]pyridin-3-yl]benzenesulfonamide | 5mg | $252 | 2021-12-16 | Buy |
| Cayman Chemical | 29226 | NSC 781406 | 10mg | $261 | 2024-03-01 | Buy |
| Cayman Chemical | 29226 | NSC 781406 ≥98% | 10mg | $288 | 2026-04-30 | Buy |
| Cayman Chemical | 29226 | NSC 781406 | 5mg | $139 | 2024-03-01 | Buy |
| Cayman Chemical | 29226 | NSC 781406 ≥98% | 5mg | $153 | 2026-04-30 | Buy |
| Cayman Chemical | 29226 | NSC 781406 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 29226 | NSC 781406 ≥98% | 1mg | $36 | 2026-04-30 | Buy |
Properties
Boiling point :775.1±70.0 °C(Predicted)
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 10mg/mL; DMSO: 20mg/mL; DMSO:PBS (pH 7.2) (1:4): 0.2mg/mL
form :A solid
pka :6.23±0.40(Predicted)
color :White to off-white
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 10mg/mL; DMSO: 20mg/mL; DMSO:PBS (pH 7.2) (1:4): 0.2mg/mL
form :A solid
pka :6.23±0.40(Predicted)
color :White to off-white
Safety Information
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Description
NSC 781406 is a dual inhibitor of PI3K and mammalian target of rapamycin (mTOR; IC50s = 2.0, 9.4, 2.7, 14, and 5.4 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ, and mTOR, respectively). It inhibits cell growth in the NCI-60 panel of cancer cell lines (mean GI50 = 65 nM). NSC 781406 (30 mg/kg) reduces tumor volume in a BEL-7404 hepatic cancer mouse xenograft model.More related product prices
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