20ALPHA-HYDROXYCHOLESTEROL
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- $19 - $1805
- Product name: 20ALPHA-HYDROXYCHOLESTEROL
- CAS: 516-72-3
- MF: C27H46O2
- MW: 402.65
- EINECS:
- MDL Number:MFCD16661190
- Synonyms:20alpha-Hydroxycholesterol (not deuterated);5-Cholestene-3B,20a-diol;Cholest-5-ene-3,20-diol, (3.beta.)-;5-cholestene-3β,20α-diol;(3S,8S,9S,10R,13S,14S,17S)-17-[(2R)-2-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol;20α-Hydroxycholesterol (not deuterated);(20S)-Cholest-5-ene-3,20-diol;(3)-Cholest-5-ene-3,20-diol
81 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biosynth
- Cayman Chemical
- ChemScene
- CSNpharm
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO(Solution)
- 1mg
- 5mg
- 10mg
- 10
- 25mg
- 50mg
- 100mg
- 250mg
- 10mM*1mLinDMSO(Solid+Solvent)
- Manufactureraablocks
- Product numberAA00DDBT
- Product description(8S,9S,10R,13S,14S,17S)-17-((R)-2-Hydroxy-6-Methylheptan-2-Yl)-10,13-Dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-Tetradecahydro-1H-Cyclopenta[A]Phenanthren-3-Ol 98%
- Packaging1mg
- Price$19
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DDBT
- Product description(8S,9S,10R,13S,14S,17S)-17-((R)-2-Hydroxy-6-Methylheptan-2-Yl)-10,13-Dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-Tetradecahydro-1H-Cyclopenta[A]Phenanthren-3-Ol 98%
- Packaging5mg
- Price$52
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DDBT
- Product description(8S,9S,10R,13S,14S,17S)-17-((R)-2-Hydroxy-6-Methylheptan-2-Yl)-10,13-Dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-Tetradecahydro-1H-Cyclopenta[A]Phenanthren-3-Ol 98%
- Packaging10mg
- Price$89
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DDBT
- Product description(8S,9S,10R,13S,14S,17S)-17-((R)-2-Hydroxy-6-Methylheptan-2-Yl)-10,13-Dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-Tetradecahydro-1H-Cyclopenta[A]Phenanthren-3-Ol 98%
- Packaging25mg
- Price$160
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DDBT
- Product description(8S,9S,10R,13S,14S,17S)-17-((R)-2-Hydroxy-6-Methylheptan-2-Yl)-10,13-Dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-Tetradecahydro-1H-Cyclopenta[A]Phenanthren-3-Ol 98%
- Packaging250mg
- Price$1016
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DDBT
- Product description(8S,9S,10R,13S,14S,17S)-17-((R)-2-Hydroxy-6-Methylheptan-2-Yl)-10,13-Dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-Tetradecahydro-1H-Cyclopenta[A]Phenanthren-3-Ol 98%
- Packaging50mg
- Price$271
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DDBT
- Product description(8S,9S,10R,13S,14S,17S)-17-((R)-2-Hydroxy-6-Methylheptan-2-Yl)-10,13-Dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-Tetradecahydro-1H-Cyclopenta[A]Phenanthren-3-Ol 98%
- Packaging100mg
- Price$462
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY225827
- Product description20(S)-Hydroxycholesterol 97.00%
- Packaging10MG
- Price$125
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY225827
- Product description20(S)-Hydroxycholesterol 97.00%
- Packaging25MG
- Price$215
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY225827
- Product description20(S)-Hydroxycholesterol 97.00%
- Packaging100MG
- Price$615
- Updated2026-05-27
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberLIP0020771
- Product description20-ALPHA-HYDROXY CHOLESTEROL 95.00%
- Packaging5MG
- Price$495.23
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7669
- Product description20(S)-Hydroxycholesterol
- Packaging10mg
- Price$222
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7669
- Product description20(S)-Hydroxycholesterol
- Packaging5mg
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7669
- Product description20(S)-Hydroxycholesterol
- Packaging10mg
- Price$380
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7669
- Product description20(S)-Hydroxycholesterol
- Packaging5mg
- Price$216
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-12316
- Product description20(S)-Hydroxycholesterol 99.29%
- Packaging10mg
- Price$152
- Updated2026-05-25
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00DDBT | (8S,9S,10R,13S,14S,17S)-17-((R)-2-Hydroxy-6-Methylheptan-2-Yl)-10,13-Dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-Tetradecahydro-1H-Cyclopenta[A]Phenanthren-3-Ol 98% | 1mg | $19 | 2026-05-28 | Buy |
| aablocks | AA00DDBT | (8S,9S,10R,13S,14S,17S)-17-((R)-2-Hydroxy-6-Methylheptan-2-Yl)-10,13-Dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-Tetradecahydro-1H-Cyclopenta[A]Phenanthren-3-Ol 98% | 5mg | $52 | 2026-05-28 | Buy |
| aablocks | AA00DDBT | (8S,9S,10R,13S,14S,17S)-17-((R)-2-Hydroxy-6-Methylheptan-2-Yl)-10,13-Dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-Tetradecahydro-1H-Cyclopenta[A]Phenanthren-3-Ol 98% | 10mg | $89 | 2026-05-28 | Buy |
| aablocks | AA00DDBT | (8S,9S,10R,13S,14S,17S)-17-((R)-2-Hydroxy-6-Methylheptan-2-Yl)-10,13-Dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-Tetradecahydro-1H-Cyclopenta[A]Phenanthren-3-Ol 98% | 25mg | $160 | 2026-05-28 | Buy |
| aablocks | AA00DDBT | (8S,9S,10R,13S,14S,17S)-17-((R)-2-Hydroxy-6-Methylheptan-2-Yl)-10,13-Dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-Tetradecahydro-1H-Cyclopenta[A]Phenanthren-3-Ol 98% | 250mg | $1016 | 2026-05-28 | Buy |
| aablocks | AA00DDBT | (8S,9S,10R,13S,14S,17S)-17-((R)-2-Hydroxy-6-Methylheptan-2-Yl)-10,13-Dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-Tetradecahydro-1H-Cyclopenta[A]Phenanthren-3-Ol 98% | 50mg | $271 | 2026-05-28 | Buy |
| aablocks | AA00DDBT | (8S,9S,10R,13S,14S,17S)-17-((R)-2-Hydroxy-6-Methylheptan-2-Yl)-10,13-Dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-Tetradecahydro-1H-Cyclopenta[A]Phenanthren-3-Ol 98% | 100mg | $462 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y225827 | 20(S)-Hydroxycholesterol 97.00% | 10MG | $125 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y225827 | 20(S)-Hydroxycholesterol 97.00% | 25MG | $215 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y225827 | 20(S)-Hydroxycholesterol 97.00% | 100MG | $615 | 2026-05-27 | Buy |
| American Custom Chemicals Corporation | LIP0020771 | 20-ALPHA-HYDROXY CHOLESTEROL 95.00% | 5MG | $495.23 | 2021-12-16 | Buy |
| ApexBio Technology | B7669 | 20(S)-Hydroxycholesterol | 10mg | $222 | 2021-12-16 | Buy |
| ApexBio Technology | B7669 | 20(S)-Hydroxycholesterol | 5mg | $125 | 2021-12-16 | Buy |
| ApexBio Technology | B7669 | 20(S)-Hydroxycholesterol | 10mg | $380 | 2026-05-06 | Buy |
| ApexBio Technology | B7669 | 20(S)-Hydroxycholesterol | 5mg | $216 | 2026-05-06 | Buy |
| Arctom | HY-12316 | 20(S)-Hydroxycholesterol 99.29% | 10mg | $152 | 2026-05-25 | Buy |
Properties
Melting point :136-137°C
Boiling point :512.3±23.0 °C(Predicted)
Density :1.03±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,2-8°C
solubility :Soluble in DMSO or in Ethanol.
form :Solid
pka :15.04±0.70(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Major Application :clinical testing
InChIKey :MCKLJFJEQRYRQT-APGJSSKUSA-N
SMILES :CC(C)CCC[C@](C)(O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
Boiling point :512.3±23.0 °C(Predicted)
Density :1.03±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,2-8°C
solubility :Soluble in DMSO or in Ethanol.
form :Solid
pka :15.04±0.70(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Major Application :clinical testing
InChIKey :MCKLJFJEQRYRQT-APGJSSKUSA-N
SMILES :CC(C)CCC[C@](C)(O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
Safety Information
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Description
20α-Hydroxy Cholesterol is an allosteric activator of the Hedgehog signaling pathway Smoothened (Smo) oncoprotein that binds at a site distinct from the canonical cyclopamine binding site. 20α-Hydroxy Cholesterol activates Hedgehog (Hh) signaling (EC50 ~ 3μM for induction of Hh reporter gene transcription in in NIH 3T3 cells). It induces Smo accumulation in primary cilia and also exhibits osteogenic activity and activates the liver X receptor (LXR).Related product price
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