4-(4-Chlorophenyl)-3-methylbut-3-en-2-oxime
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- $48 - $1555
- Product name: 4-(4-Chlorophenyl)-3-methylbut-3-en-2-oxime
- CAS: 55224-94-7
- MF: C11H12ClNO
- MW: 209.67
- EINECS:
- MDL Number:MFCD00102250
- Synonyms:AP-18;4-(4-Chlorophenyl)-3-methyl-3-buten-2-oneoxime;4-(4-Chlorophenyl)-3-methylbut-3-en-2-oxime;3-Buten-2-one, 4-(4-chlorophenyl)-3-methyl-, oxime;4-(4-Chlorophenyl)-3-methylbut-3-en-2-one oxime;ganglia,TRP Channel,nerves,pain,AP18,Transient receptor potential channels,AP-18,AP 18,inhibit,nociceptive,root,hyperalgesia,Inhibitor,transduction,dorsal;AP-18, TRPA1 receptor antagonist;AP 18, 10 mM in DMSO
49 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- ApexBio Technology
- Arctom
- AvaChem
- Biosynth
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10mg
- 10
- 5mg
- 25mg
- 50
- 50mg
- 100MG
- 10mM*1mLinDMSO(Solid+Solvent)
- 500MG
- 10mM*1mLinDMSO(Solution)
- Manufactureraablocks
- Product numberAA00DEVV
- Product descriptionAP-18
- Packaging50mg
- Price$178
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DEVV
- Product descriptionAP-18
- Packaging25mg
- Price$119
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DEVV
- Product descriptionAP-18
- Packaging10mg
- Price$72
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DEVV
- Product descriptionAP-18
- Packaging5mg
- Price$52
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227141
- Product descriptionAP 18 97.00%
- Packaging25MG
- Price$145
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227141
- Product descriptionAP 18 97.00%
- Packaging500MG
- Price$910
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227141
- Product descriptionAP 18 97.00%
- Packaging100MG
- Price$380
- Updated2026-05-27
- Buy
- ManufacturerApexBio Technology
- Product numberB7349
- Product descriptionAP18
- Packaging5mg
- Price$62
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7349
- Product descriptionAP 18
- Packaging5mg
- Price$83
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7349
- Product descriptionAP18
- Packaging10mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7349
- Product descriptionAP 18
- Packaging10mg
- Price$126
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7349
- Product descriptionAP18
- Packaging25mg
- Price$219
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7349
- Product descriptionAP 18
- Packaging25mg
- Price$293
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7349
- Product descriptionAP18
- Packaging50mg
- Price$374
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7349
- Product descriptionAP 18
- Packaging50mg
- Price$498
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-W014421
- Product descriptionAP-18 99.61%
- Packaging50mg
- Price$228
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00DEVV | AP-18 | 50mg | $178 | 2026-05-28 | Buy |
| aablocks | AA00DEVV | AP-18 | 25mg | $119 | 2026-05-28 | Buy |
| aablocks | AA00DEVV | AP-18 | 10mg | $72 | 2026-05-28 | Buy |
| aablocks | AA00DEVV | AP-18 | 5mg | $52 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y227141 | AP 18 97.00% | 25MG | $145 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y227141 | AP 18 97.00% | 500MG | $910 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y227141 | AP 18 97.00% | 100MG | $380 | 2026-05-27 | Buy |
| ApexBio Technology | B7349 | AP18 | 5mg | $62 | 2021-12-16 | Buy |
| ApexBio Technology | B7349 | AP 18 | 5mg | $83 | 2026-05-06 | Buy |
| ApexBio Technology | B7349 | AP18 | 10mg | $95 | 2021-12-16 | Buy |
| ApexBio Technology | B7349 | AP 18 | 10mg | $126 | 2026-05-06 | Buy |
| ApexBio Technology | B7349 | AP18 | 25mg | $219 | 2021-12-16 | Buy |
| ApexBio Technology | B7349 | AP 18 | 25mg | $293 | 2026-05-06 | Buy |
| ApexBio Technology | B7349 | AP18 | 50mg | $374 | 2021-12-16 | Buy |
| ApexBio Technology | B7349 | AP 18 | 50mg | $498 | 2026-05-06 | Buy |
| Arctom | HY-W014421 | AP-18 99.61% | 50mg | $228 | 2026-05-26 | Buy |
Properties
Boiling point :348.381±34.00 °C(Press: 760.00 Torr)(predicted)
Density :1.099±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
pka :11.734±0.10(predicted)
form :solid
color :white to off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
InChI :1S/C11H12ClNO/c1-8(9(2)13-14)7-10-3-5-11(12)6-4-10/h3-7,14H,1-2H3/b8-7+,13-9+
InChIKey :MHTJEUOFLVQMCL-NJHPPEEMSA-N
SMILES :CC(=C/c1ccc(Cl)cc1)\C(C)=N\O
Density :1.099±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
pka :11.734±0.10(predicted)
form :solid
color :white to off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
InChI :1S/C11H12ClNO/c1-8(9(2)13-14)7-10-3-5-11(12)6-4-10/h3-7,14H,1-2H3/b8-7+,13-9+
InChIKey :MHTJEUOFLVQMCL-NJHPPEEMSA-N
SMILES :CC(=C/c1ccc(Cl)cc1)\C(C)=N\O
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
AP-18 is a channel blocker which reversibly inhibits TRPA1 (IC50 = 3.1 and 4.5 μM, human and mouse, respectively). It has minimal effect on TRPV1-4 or TRPM8. AP-18 has been used to study TRPA1 signaling in mice and rats as well as in vitro.More related product prices
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Suppliers and manufacturers
BOC Sciences
J & K SCIENTIFIC LTD.
3B Pharmachem (Wuhan) International Co.,Ltd.
Shanghai TaoSu Biochemical Technology Co., Ltd.
Sigma-Aldrich
EMMX Biotechnology LLC
Shanghai EFE Biological Technology Co., Ltd.
Jinan Yaoyan Pharmaceutical Co., Ltd.
Shenzhen Polymeri Biochemical Technology Co., Ltd.




